12 patents
Utility
Substituted Tetracycline Compounds
23 Dec 21
The present invention pertains, at least in part, to novel substituted tetracycline compounds.
Paul Abato, Todd Bowser
Filed: 4 Jan 21
Utility
Methods of Treating Mycobacterial Infections Using Tetracycline Compounds
11 Nov 21
The present invention provides methods of treating mycobacterial infections or mycobacterial diseases by administering a tetracycline compound, e.g., omadacycline, or a pharmaceutically acceptable salt thereof.
Michael Henry Cynamon, Michael P. Draper, Judith N. Steenbergen, S. Ken Tanaka
Filed: 3 Sep 19
Utility
Minocycline compounds for biodefense
28 Sep 21
Methods of treating or preventing a bacterial infection in a subject are disclosed herein, wherein the bacterial infection is caused by a bacterium which can be used as a biological weapon.
Michael P. Draper, S. Ken Tanaka
Filed: 24 Feb 20
Utility
Minocycline Compounds and Methods of Use Thereof
29 Apr 21
Methods and compositions for using a tetracycline compound to treat bacterial infections are described.
Sean M. Johnston, Robert D. Arbeit, Thomas J. Bigger, Dennis P. Molnar, S. Ken Tanaka
Filed: 5 Jan 21
Utility
9-Aminomethyl Minocycline Compounds And Use Thereof In Treating Community-Acquired Bacterial Pneumonia (CABP)
25 Feb 21
The invention disclosed herein provides a method for treating Community-Acquired Bacterial Pneumonia (CABP) using 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, in either oral or IV doses or a combination of both.
Evangelos L. Tzanis, Paul McGovern, Amy L. Manley, Lynne Garrity-Ryan, S. Ken Tanaka
Filed: 4 Nov 20
Utility
Process for Making Sarecycline Hydrochloride
21 Jan 21
The described invention relates to sarecycline, related compounds, intermediates and salts thereof and processes for preparing the same.
Giovanni PALOMBI, Eugenio CASTELLI, Giuseppe MOTTA, Meinrad BRENNER, Ruiliang LU, Shaozhi HUANG, William Paul ARMSTRONG, Gajanan JOSHI, Farzaneh SEYEDI, Sean JOHNSTON
Filed: 5 Apr 19
Utility
9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (CABP)
16 Nov 20
The invention disclosed herein provides a method for treating Community-Acquired Bacterial Pneumonia (CABP) using 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, in either oral or IV doses or a combination of both.
Evangelos L. Tzanis, Paul McGovern, Amy L. Manley, Lynne Garrity-Ryan, S. Ken Tanaka
Filed: 9 Jul 19
Utility
Minocycline Compounds for Biodefense
21 Oct 20
Methods of treating or preventing a bacterial infection in a subject are disclosed herein, wherein the bacterial infection is caused by a bacterium which can be used as a biological weapon.
Michael P. Draper, S. Ken Tanaka
Filed: 23 Feb 20
Utility
Minocycline Compounds and Methods of Use Thereof
16 Sep 20
Methods and compositions for using a tetracycline compound to treat bacterial infections are described.
Sean M. Johnston, Robert D. Arbeit, Thomas J. Bigger, Dennis P. Molnar, S. Ken Tanaka
Filed: 16 Jan 20
Utility
Methods for Treating and Preventing C. Difficile Infection
9 Sep 20
Methods of treating or preventing a C. difficile infection and the associated pathological conditions related to C. difficile infection, are disclosed.
S. Ken Tanaka, Michael P. Draper
Filed: 5 Dec 19
Utility
Crystalline Salts of (4S,4AS,5AR,12AS)-4-DIMETHYLAMINO-3,10,12,12A-TETRAHYDROXY-7-[(METHOXY(METHYL)AMINO)-METHYL]-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-NAPHTHACENE-2-CARBOXYLIC Acid Amide and Methods of Using the Same
22 Jan 20
A crystalline mono hydrochloride salt of (4S,4aS,5aR,12aS)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide is disclosed having improved stability.
Catherine COULTER, Sean M. JOHNSTON, Farzaneh SEYEDI
Filed: 14 May 19
Utility
9-Aminomethyl Minocycline Compounds And Use Thereof In Treating Community-Acquired Bacterial Pneumonia (CABP)
8 Jan 20
The invention disclosed herein provides a method for treating Community-Acquired Bacterial Pneumonia (CABP) using 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof, in either oral or IV doses or a combination of both.
Evangelos L. Tzanis, Paul McGovern, Amy L. Manley, Lynne Garrity-Ryan, S. Ken Tanaka
Filed: 9 Jul 19
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