9 patents
Utility
Cyclic compounds as receptor modulating therapeutics and methods and uses thereof
18 Nov 21
Lorna Mitchell, Hamish Toop, Belinda Huff, Justin Ripper, Rajinder Singh, Christophe Morice, Jean-Marie Contreras, Patrick Bazzini, Laurent Schaeffer, Mathieu Michaut
Filed: 18 Oct 19
Utility
Pain Treating Compounds and Uses Thereof
29 Jul 21
Belinda HUFF, Courtney HOLLIS, Hamish TOOP, Nathan KUCHEL, Lorna Helen MITCHELL, Rajinder SINGH, Thomas AVERY, Celine MICHAUT-SIMON, Jean-Marie CONTRERAS, Christophe MORICE
Filed: 17 May 19
Utility
Modulators of Ion Channel Receptors and Uses Thereof
29 Jul 21
Compounds useful in the modulation of ion channel activity in cells are disclosed herein.
Belinda HUFF, Courtney HOLLIS, Hamish TOOP, Nathan KUCHEL, Lorna Helen MITCHELL, Rajinder SINGH
Filed: 17 May 19
Utility
Method for Treating Acute Myeloid Leukemia
17 Jun 21
The present invention relates to a method for the treatment of acute myeloid leukemia (AML) with medicaments useful for same.
Tina Lavranos
Filed: 17 Oct 18
Utility
Method of Monitoring Response to a Treatment
20 May 21
The present invention relates to the field of pharmacogenomics.
Tina LAVRANOS, Kristen GEORGIOU
Filed: 12 Apr 19
Utility
Pharmaceutical Combination and Uses Thereof
11 Mar 21
The invention relates to pharmaceutical combinations comprising a vascular disrupting agent, in particular the tubulin polymerisation inhibitor BNC105, and an immunotherapeutic agent, in particular an anti-PD-L1, PD-1 or CTLA-4 antibody, and use thereof in the treatment of cancer.
Gabriel KREMMIDIOTIS, Tina LAVRANOS, Daniel INGLIS
Filed: 23 Nov 20
Utility
Isoxazolyl Compounds As Receptor Modulating Compounds and Methods and Uses Thereof
16 Dec 20
The present invention relates generally to chemical compounds and methods for their use and preparation.
Justin Anthony RIPPER, Patrick BAZZINI, Jean-Marie CONTRERAS, Nicolas FEICHTER, Christophe MORICE, Laurent SCHAEFFER, Cindy STAHL
Filed: 25 Nov 18
Utility
Antibody Drug Conjugates That Bind LGR5
15 Apr 20
Embodiments of the methods and compositions provided herein relate to antibody drug conjugates comprising an antibody or antigen binding fragment thereof that specifically binds to human LGR5 in which the antibody or antigen binding fragment thereof is conjugated to a therapeutic agent, such as a drug, via a linker.
Christopher L. Reyes, Peter Chu
Filed: 15 Jun 17
Utility
Combination Therapy for Treating Proliferative Diseases
4 Mar 20
The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer.
Gabriel Kremmidiotis, Annabell Leske, Tina Lavranos
Filed: 8 Nov 19
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