23 patents
Page 2 of 2
Utility
Engineered meganucleases specific for recognition sequences in the hepatitis B virus genome
25 May 20
The present invention encompasses engineered meganucleases which recognize and cleave a recognition sequence within an open reading frame (ORF) of the genome of at least two genotypes of the Hepatitis B virus (HBV).
Derek Jantz, James Jefferson Smith
Filed: 12 Oct 17
Utility
Self-limiting viral vectors encoding nucleases
25 May 20
Disclosed herein are viral vectors for use in recombinant molecular biology techniques.
Derek Jantz, James Jefferson Smith, Michael G. Nicholson
Filed: 19 Jun 16
Utility
Treatment of retinitis pigmentosa using engineered meganucleases
30 Mar 20
Disclosed are recombinant meganucleases engineered to recognize and cleave recognition sequences present in a mutant RHO P23H allele.
Victor Bartsevich, Derek Jantz, James Jefferson Smith, Michael G. Nicholson
Filed: 7 Sep 16