41 patents
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Utility
Compositions and Methods for Delivering Cannabinoids to Skin
4 Nov 21
Provided herein are compositions for delivering one or more cannabinoids to the skin of a subject and methods of using the compositions to deliver the one or more cannabinoids to the skin of a subject.
Diva CHAN, Ro OTERI, Ashlee NUNES
Filed: 14 Jul 21
Utility
Maltose Dependent Degrons, Maltose-responsive Promoters, Stabilization Constructs, and Their Use In Production of Non-catabolic Compounds
29 Jul 21
The present disclosure relates to the use of a maltose dependent degron to control stability of a protein of interest fused thereto at the post-translational level.
Penelope R. CHUA, Hanxiao JIANG, Adam Leon MEADOWS
Filed: 2 Apr 21
Utility
Methods for Controlling Fermentation Feed Rates
29 Jul 21
The present disclosure relates to methods for enhancing productivity or yield in fermentation.
Joshua LENG
Filed: 11 Jul 19
Utility
Methods for Recovering Water-immiscible Isoprenoid Compounds from Microbial Biomass
29 Jul 21
A method for recovering one or more water immiscible compounds comprising acidifying and disrupting the microbial biomass; heating the acidified, disrupted microbial biomass to form a heated, acidified disrupted microbial biomass; and contacting the heated, acidified, disrupted microbial biomass with a disulfonated surfactant in an amount sufficient to release at least 30% of the one or more water immiscible compounds from the microbial biomass.
Ronald Ray HENRY, Joshua Steven LENG
Filed: 27 Jun 19
Utility
Compositions and Methods for Delivering Cannabinoids to Skin
8 Jul 21
Provided herein are compositions for delivering one or more cannabinoids to the skin of a subject and methods of using the compositions to deliver the one or more cannabinoids to the skin of a subject.
Diva CHAN, Ro OTERI, Ashlee NUNES
Filed: 19 Mar 21
Utility
Cells and Methods for Selection Based Assay
24 Jun 21
Cells and methods for screening inhibitors against a heterologous target protein are disclosed.
Andrew HORWITZ, Jessica Mai WALTER, Chia-Hong TSAI
Filed: 28 Aug 19
Utility
Methods for Stabilizing Production of Acetyl-coenzyme a Derived Compounds
27 May 21
The present disclosure relates to the use of a switch for the production of heterologous non-catabolic compounds in microbial host cells.
Hanxiao JIANG, Adam MEADOWS
Filed: 27 Jan 21
Utility
Synthesis of E,e-farnesol, Farnesyl Acetate and Squalene from Farnesene Via Farnesyl Chloride
22 Apr 21
The present disclosure provides methods for preparing polyunsaturated hydrocarbons, such as E,E-farnesol, farnesyl acetate and squalene, by base catalyzed addition of a dialkylamine to a 3-methylene-1-alkene, such as farnesene.
Karl Joseph FISHER, Frank Xavier WOOLARD
Filed: 7 Jun 19
Utility
Block Copolymer, Method for Producing Same, Rubber Composition Using Said Block Copolymer, and Tire
21 Jan 21
The present invention relates to a block copolymer that contains a polymer block A containing a farnesene-derived monomer unit (a1) and a random copolymer block B containing a C12 or lower conjugated diene-derived monomer unit (b1) and an aromatic vinyl compound-derived monomer unit (b2), the block copolymer having a ratio by mass of the polymer block A to the random copolymer block B (A/B) of 30/70 to 0.5/99.5, a content of the aromatic vinyl compound-derived monomer unit (b2) in the random copolymer block B of 1 to 50% by mass, and a weight average molecular weight (Mw) of 100,000 to 5,000,000.
Daisuke KODA
Filed: 28 Mar 19
Utility
Maltose Dependent Degrons, Maltose-responsive Promoters, Stabilization Constructs, and Their Use In Production of Non-catabolic Compounds
23 Dec 20
The present disclosure relates to the use of a maltose dependent degron to control stability of a protein of interest fused thereto at the post-translational level.
Penelope R. CHUA, Hanxiao JIANG, Adam Leon MEADOWS
Filed: 3 Sep 20
Utility
Compositions Containing Bio-based Farnesene or Compounds Derived Therefrom and Their Use In Consumer and Industrial Products
16 Dec 20
The present invention provides compositions and methods of using the compositions as personal care products and other consumer and industrial products, wherein the compositions comprise bio-based farnesene and/or compounds derived from the bio-based farnesene.
Ross Eppler, Diva CHAN
Filed: 25 Jun 20
Utility
Methods for Genomic Integration
11 Nov 20
Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. in certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. in some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker.
Andrew HORWITZ, Kristy Michelle HAWKINS, Max SCHUBERT, Wayne SZETO
Filed: 10 Mar 20
Utility
Methods for Stabilizing Production of Acetyl-coenzyme a Derived Compounds
26 Aug 20
The present disclosure relates to the use of a switch for the production of heterologous non-catabolic compounds in microbial host cells.
Penelope R. CHUA, Adam MEADOWS
Filed: 1 Jan 20
Utility
Methods for Genetic Engineering Kluyveromyces Host Cells
19 Aug 20
The invention provides methods for genetically engineering Kluyveromyces.
Yoseph TSEGAYE
Filed: 11 Sep 18
Utility
Methods for Genomic Integration for Kluyveromyces Host Cells
19 Aug 20
The present invention provides high efficiency targeted and marker-less single or simultaneous multiple integrations using nucleases and a stable plasmid in Kluyveromyces host cells.
Jessica WALTER
Filed: 11 Sep 18
Utility
Methods for Genomic Integration In Pichia and Other Host Cells
1 Jul 20
The present invention provides high efficiency targeted and marker-less single, double, triple, quadruple, and quintuple integrations by using CRISPR in host cells, including Pichia.
Hanxiao JIANG
Filed: 11 Sep 18
Utility
Process for Recovering Isoprenoids Produced by Microorganisms
10 Jun 20
Maha Bahi, Anthony Hutin, Fernando Leal-Calderon
Filed: 31 Jul 18
Utility
Pisum Sativum Kaurene Oxidase for High Efficiency Production of Rebaudiosides
27 May 20
Provided herein are compositions and methods for improved production of steviol glycosides in a host cell.
Gale WICHMANN, Aditi Khankhoje, Tina Mahatdejkul-Meadows
Filed: 9 Aug 18
Utility
Hydrogenated Block Copolymer
11 Mar 20
A hydrogenated block copolymer prepared by hydrogenating a block copolymer that contains a polymer block (A) containing a structural unit derived from an aromatic vinyl compound, a polymer block (B) containing a structural unit derived from farnesene, and a polymer block (C) containing a structural unit derived from a conjugated diene except farnesene, wherein the block copolymer contains at least two above polymer blocks (A), at least one above polymer block (B) and at least one above polymer block (C), and wherein at least one above polymer block (B) is at the terminal, and the hydrogenation rate of the carbon-carbon double bond in the polymer block (B) and the polymer block (C) is 50 mol % or more.
Yosuke UEHARA, Hiromitsu SASAKI, Daisuke KONISHI, Masahiro KATO
Filed: 11 Nov 19
Utility
Co-production of a Sesquiterpene and a Carotenoid
29 Jan 20
Provided herein are compositions and methods for co-production and recovery of two or more isoprenoids from a single recombinant cell.
Christopher J. PADDON, Victor HOLMES, Chia-Hong TSAI, Yoseph TSEGAYE, Phoebe YEH
Filed: 24 Jan 18