7 patents
Utility
Methods of treating intraocular pressure with activators of Tie-2
23 Mar 21
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta.
Kevin Gene Peters
Filed: 22 Sep 16
Utility
Multispecific antibodies that target HPTP-β (VE-PTP) and VEGF
19 Jan 21
The disclosure provides compositions comprising multi-specific compounds, including a compound that targets a phosphatase and a receptor tyrosine kinase agonist.
Kevin Peters
Filed: 23 Sep 19
Utility
HPTP-Beta inhibitors
7 Dec 20
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta.
John Janusz, James Copp, Kevin Peters
Filed: 6 May 18
Utility
Methods for treating vascular leak syndrome and cancer
26 Oct 20
Disclosed are methods for treating Vascular Leak Syndrome and preventing cancer metastasis.
Kevin Peters, Robert Shalwitz
Filed: 22 Oct 18
Utility
Humanized monoclonal antibodies that target protein tyrosine phosphatase-beta (HPTP-β/VE-PTP)
30 Mar 20
The disclosure provides compositions and methods for the treatment of ocular conditions associated with angiogenesis comprising administering an antibody that targets a tyrosine phosphatase inhibitor in a subject.
Kevin Peters, Michael Allen Flynn
Filed: 4 Nov 18
Utility
Methods of treating ocular conditions by administering humanized monoclonal antibodies that target VE-PTP (HPTP-beta)
23 Mar 20
The disclosure provides compositions and methods for the treatment of ocular conditions associated with angiogenesis comprising administering an antibody that targets a tyrosine phosphatase inhibitor in a subject.
Kevin Peters, Michael Allen Flynn
Filed: 4 Nov 18
Utility
Human protein tyrosine phosphatase inhibitors and methods of use
4 Nov 19
The present disclosure relates to compounds effective as human protein tyrosine phosphatase beta (HPTP-β) inhibitors thereby regulating angiogenesis.
Jeffrey Lyle Gray, Kande K. D. Amarasinghe, Cynthia Monesa Clark, Ryan Matthew Nichols, Matthew B. Maier
Filed: 14 Sep 17
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