60 patents
Page 2 of 3
Utility
Methods for Treating Cancer
27 Oct 22
Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject by administering to the subject a therapeutically effective amount of a combination of palbociclib and RAD1901.
Gary HATTERSLEY
Filed: 29 Jun 22
Utility
Estrogen Receptor-modulating Compounds
20 Oct 22
Described herein are compounds that are estrogen receptor modulators.
Chris MILLER
Filed: 31 May 22
Utility
Stable Cannabinoid Formulations
8 Sep 22
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
Filed: 18 Feb 22
Utility
Estrogen Receptor-modulating Compounds
8 Sep 22
Described herein are compounds that are estrogen receptor modulators.
Chris P. MILLER
Filed: 21 Jul 20
Utility
Methods for treating cancer
16 Aug 22
Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject by administering to the subject a therapeutically effective amount of a combination of palbociclib and RAD1901.
Gary Hattersley
Filed: 24 Sep 19
Utility
Estrogen receptor-modulating compounds
12 Jul 22
Described herein are compounds that are estrogen receptor modulators.
Chris Miller
Filed: 22 Jan 19
Utility
Methods for Detecting Neutralizing Antibodies to Parathyroid Hormone (PTH) and Parathyroid Hormone-related Peptide (PTHRP) Analog
30 Jun 22
The present disclosure is directed to methods (e.g., in vitro methods) for detecting the presence of neutralizing antibodies to PTH or PTHrP analog in a sample.
Heidi K. Chandler
Filed: 7 Jan 22
Utility
Methods of Improving Spinal Fusion with Abaloparatide
23 Jun 22
Provided herein are methods of enhancing spinal fusion and bone formation in subjects with spinal fractures, deformities or instability in the spine.
Beate Klara Maria Mannstadt, Bruce Mitlak
Filed: 11 Mar 22
Utility
Stable Cannabinoid Formulations
16 Jun 22
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Kiran Kumar VANGARA, Huaguang LI, Ningxin YAN, Hung Q. Nguyen, Venkat R. GOSKONDA
Filed: 22 Dec 21
Utility
Processes and Compounds
26 May 22
Useful processes of preparation and intermediates useful for the preparation of Compound 1, a selective estrogen receptor alpha (ERα) modulator/degrader (SERM/SERD), having utility for the treatment of ER+ cancers including breast cancer are described.
Michael MARKEY
Filed: 11 Feb 20
Utility
Stable cannabinoid formulations
17 May 22
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
Filed: 31 Jul 15
Utility
USES OF PTHrP ANALOGUE IN REDUCING FRACTURE RISK
28 Apr 22
Disclosed herein are PTHrP or analogues thereof, such as abaloparatide, for preventing or reducing bone fractures in subjects in need thereof, as well as methods of using PTHrP or analogues thereof to prevent or reduce bone fractures.
Gary Hattersley
Filed: 10 Sep 21
Utility
Stable Cannabinoid Formulations
28 Apr 22
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Kiran Kumar VANGARA, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
Filed: 5 Nov 21
Utility
Methods for Treating Cancer
14 Apr 22
Disclosed herein are methods of treating one or more tumors by administering to the subject a therapeutically effective amount of a combination of RAD1901 or solvates (e.g., hydrate) or salts thereof and one or more second therapeutic agent(s) (e.g., everolimus).
Gary HATTERSLEY
Filed: 25 Oct 21
Utility
Stable Cannabinoid Formulations
24 Feb 22
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
Filed: 5 Nov 21
Utility
Methods for detecting neutralizing antibodies to parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHRP) analog
22 Feb 22
The present disclosure is directed to methods (e.g., in vitro methods) for detecting the presence of neutralizing antibodies to PTH or PTHrP analog in a sample.
Heidi K. Chandler
Filed: 7 Jul 21
Utility
Polymorphic Forms of RAD1901-2HCL
17 Feb 22
Various polymorphic forms of RAD1901-2HCl, including three crystalline and amorphous forms, are prepared and characterized.
Michael Paul Cruskie, JR., Joshua Kyle Bolger, Jonathan Blake McKenzie, Pratik Sheth, Richard Edwards, Alex Eberlin, Michael Markey
Filed: 14 Sep 21
Utility
Methods for Treating Cancer In Models Harboring ESR1 Mutations
20 Jan 22
Disclosed herein are methods of treating a drug resistant estrogen receptor alpha-positive cancer in a subject having a mutant estrogen receptor alpha, the method comprising administering to the subject a therapeutically effective amount of elacestrant, or a pharmaceutically acceptable salt or solvate thereof, wherein the mutant estrogen receptor alpha comprises one or more mutations selected from the group consisting of D538G, Y537X1, L536X2, P535H, V534E, S463P, V392I, E380Q and combinations thereof, wherein: X1 is S, N, or C; and X2 is R or Q.
Hitisha PATEL, Teeru BIHANI, Heike ARLT, Nianjun TAO
Filed: 6 Dec 19
Utility
Stable cannabinoid formulations
18 Jan 22
The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
Filed: 28 May 15
Utility
Abaloparatide Formulations and Methods of Testing, Storing, Modifying, and Using Same
6 Jan 22
Provided herein are newly discovered methods of analyzing abaloparatide samples for abaloparatide isomers.
Greg Williams, Naveen Palwai, David Hanley
Filed: 1 Apr 21