11 patents
Utility
Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
12 Dec 23
The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
Marino Nebuloni, Patrizia Colombo
Filed: 28 Oct 20
Utility
Cyclobenzaprine treatment for agitation, psychosis and cognitive decline in dementia and neurodegenerative conditions
28 Nov 23
Compositions comprising cyclobenzaprine, and methods for the treatment or prevention of agitation, psychosis and/or cognitive decline and associated symptoms thereof in dementia and other neurodegenerative conditions.
Herbert W. Harris, Seth Lederman
Filed: 11 Dec 18
Utility
Radio-protective and chemo-protective substituted thiols
31 Jan 23
Philip S. Schein, Darryl C. Rideout
Filed: 7 May 21
Utility
Analogs of cyclobenzaprine and amitriptyline
6 Dec 22
The present invention relates to cyclobenzaprine analogs and amitriptyline analogs, including deuterated forms useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.
Seth Lederman, Darryl Rideout, Greg Sullivan
Filed: 13 Jul 18
Utility
Magnesium-containing oxytocin formulations and methods of use
19 Jul 22
Disclosed are magnesium-containing oxytocin peptide formulations or compositions comprising an oxytocin peptide and a magnesium salt that produces synergistic analgesia when used in treating pain.
David C. Yeomans, Dean Carson, Ramachandran Thirucote
Filed: 7 Jan 16
Utility
Eutectic formulations of cyclobenzaprine hydrochloride
8 Jun 21
The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol.
Seth Lederman, Marino Nebuloni
Filed: 22 Jul 19
Utility
Tianeptine oxalate salts and polymorphs
16 Mar 21
Stefano Luca Giaffreda, Enrico Modena, Serena Fabbroni, Michel Chiarucci, Mark T. Edgar
Filed: 9 Oct 19
Utility
Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
14 Dec 20
The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
Marino Nebuloni, Patrizia Colombo
Filed: 23 Sep 18
Utility
Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
14 Dec 20
The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
Marino Nebuloni, Patrizia Colombo
Filed: 23 Sep 18
Utility
Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
10 Aug 20
The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol or Amitriptyline HCl and mannitol.
Marino Nebuloni, Patrizia Colombo
Filed: 2 Jun 19
Utility
Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine
27 Jul 20
The present invention relates to methods for the treatment or prevention of fatigue associated with disordered sleep, for example, in multiple sclerosis, fibromyalgia, Fabry's disease, Parkinson's disease, or traumatic brain injury, using cyclobenzaprine.
Seth Lederman, Herb Harris
Filed: 8 Aug 19
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