16 patents
Utility
Analogs of deutetrabenazine, their preparation and use
14 Nov 23
The disclosure is directed to deutetrabenazine analogs, compositions comprising same and methods of detecting same in compositions comprising deutetrabenazine.
Chengzhi Zhang, James Kerr
Filed: 15 Mar 18
Utility
Methods for the treatment of abnormal involuntary movement disorders
16 May 23
Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.
David Stamler, Michael Fangching Huang
Filed: 2 Aug 17
Utility
Methods for the treatment of abnormal involuntary movement disorders
31 Jan 23
Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.
David Stamler, Michael Fangching Huang
Filed: 2 Oct 17
Utility
Methods for the treatment of abnormal involuntary movement disorders
20 Sep 22
Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.
David Stamler, Michael Fangching Huang
Filed: 25 Mar 21
Utility
Methods for the treatment of abnormal involuntary movement disorders
14 Jun 22
Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.
David Stamler, Michael Huang
Filed: 21 Jan 21
Utility
Methods for the treatment of dyskinesia in cerebral palsy
10 May 22
The disclosure is directed to methods of treating dyskinesia in cerebral palsy in human patients using deutetrabenazine and its active metabolites.
Juha-Matti Savola, Mark Forrest Gordon, Frank Schneider
Filed: 13 Dec 19
Utility
Osmotic dosage forms comprising deutetrabenazine and methods of use thereof
26 Apr 22
Provided herein are osmotic dosage forms containing deutetrabenazine for use in the treatment of, e.g., hyperkinetic movement disorders.
Parag Shah, Mayank Joshi, Soumen Pattanayek, Divyang Patel, Sandeep Pandita
Filed: 10 Jun 21
Utility
Analogs of deutetrabenazine, their preparation and use
23 Nov 21
The disclosure is directed to deutetrabenazine analogs, compositions comprising same and methods of detecting same in compositions comprising deutetrabenazine.
Chengzhi Zhang, James Kerr
Filed: 25 Sep 19
Utility
Formulations and pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
15 Jun 21
The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.
Andreas Sommer, Chengzhi Zhang, John Carter, John Charles Arthur, Margaret Bradbury, Thomas George Gant, Manouchehr Shahbaz
Filed: 13 Nov 19
Utility
Pharmaceutical formulations
6 Apr 21
The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.
Andreas Sommer, Chengzhi Zhang, John Carter, John Arthur, Margaret Bradbury
Filed: 12 Jul 19
Utility
Methods for the treatment of abnormal involuntary movement disorders
30 Mar 21
Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity, movement disorders, and related conditions.
David Stamler, Michael Fangching Huang
Filed: 19 Jul 18
Utility
Dimethoxyphenyl inhibitors of vesicular monoamine transporter 2
27 Jul 20
Chengzhi Zhang
Filed: 16 Feb 16
Utility
Cyclopropane carboxamide modulators of cystic fibrosis transmembrane conductance regulator
22 Jun 20
Chengzhi Zhang, Justin Chakma
Filed: 18 Dec 18
Utility
Deuterium-substituted pyridin- and pyrimidin-2-yl-methylamine compounds
20 Apr 20
Chengzhi Zhang
Filed: 19 Sep 17
Utility
Aminopyrimidine inhibitors of tyrosine kinase
24 Feb 20
Chengzhi Zhang
Filed: 20 Apr 14
Utility
Methods of manufacturing benzoquinoline compounds
23 Dec 19
Chengzhi Zhang
Filed: 28 Mar 17
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