6 patents
Utility
Compositions for Treating Dry Age-related Macular Degeneration (Amd)
11 Jan 24
The present disclosure relates to methods of treating dry age-related macular degeneration (dry AMD), comprising administering to a subject in need thereof, a therapeutically effective amount of a compound or pharmaceutical composition according to any embodiment described herein.
Anthony CAGGIANO, Susan CATALANO, Mary HAMBY, Nicholas IZZO, Gary LOOK, Gilbert RISHTON
Filed: 10 Dec 21
Utility
Method of Decreasing Amyloid Beta Monomer Levels In Patients with Cognitive Decline
30 Mar 23
The present disclosure relates to methods of decreasing amyloid β monomers and methods of treating cognitive decline in a subject, wherein the treatment results in an increase in amyloid β oligomers and a reduction in cognitive decline.
Susan CATALANO, Nicholas IZZO
Filed: 12 Feb 21
Utility
Compositions for Treating Neurodegenerative Diseases
10 Nov 22
The present disclosure relates to novel compounds, pharmaceutical compositions containing the compounds and methods of using the compounds and pharmaceutical compositions for treating neurodegerative diseases, including Alzheimer's disease and cognitive decline.
Gilbert M. RISHTON, Gary C. LOOK, Susan M. CATALANO
Filed: 29 Nov 21
Utility
Isoindoline Compositions and Methods for Treating Neurodegenerative Disease
14 Jan 21
Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.
Gilbert M. Rishton, Susan M. Catalano, Gary C. Look
Filed: 6 Feb 20
Utility
Isoindoline Compositions and Methods for Treating Neurodegenerative Disease
28 Oct 20
The present invention is directed to methods of treating Alzheimer's disease.
Susan M. CATALANO, Nicholas J. IZZO
Filed: 31 Oct 18
Utility
Compositions for Treating Neurodegenerative Diseases
23 Sep 20
The present disclosure relates to novel compounds, pharmaceutical compositions containing the compounds and methods of using the compounds and pharmaceutical compositions for treating neurodegenerative diseases, including Alzheimer's disease and cognitive decline.
Gilbert M. RISHTON, Gary C. LOOK, Susan M. CATALANO
Filed: 14 May 18
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