16 patents
Utility
Systems and Methods for Image Manipulation of a Digital Stack of Tissue Images
6 Jul 23
Described herein are systems, devices, and methods for aiding a user to scroll through or otherwise manipulate a stack of medical and tissue images.
Mark Forchette, John Seamans
Filed: 15 Mar 23
Utility
Method of Characterizing Tissue of a Patient
23 Mar 23
A method for characterizing tissue of a patient, including receiving acoustic data derived from the interaction between the tissue and the acoustic waves irradiating the tissue; generating a morphology rendering of the tissue from the acoustic data, in which the rendering represents at least one biomechanical property of the tissue; determining a prognostic parameter for a region of interest in the rendering, in which the prognostic parameter incorporates the biomechanical property; and analyzing the prognostic parameter to characterize the region of interest.
Nebojsa Duric, Peter John Littrup
Filed: 28 Jun 22
Utility
Methods and Systems for Cancer Risk Assessment Using Tissue Sound Speed and Stiffness
13 Oct 22
A method of analyzing an image of a volume of tissue to determine a risk of developing breast cancer using a volume averaged sound speed within the volume.
Nebojsa Duric, Mark Sak, Peter Littrup, Cuiping Li, Olivier Roy
Filed: 14 Jun 22
Utility
Method of characterizing tissue of a patient
2 Aug 22
A method for characterizing tissue of a patient, including receiving acoustic data derived from the interaction between the tissue and the acoustic waves irradiating the tissue; generating a morphology rendering of the tissue from the acoustic data, in which the rendering represents at least one biomechanical property of the tissue; determining a prognostic parameter for a region of interest in the rendering, in which the prognostic parameter incorporates the biomechanical property; and analyzing the prognostic parameter to characterize the region of interest.
Nebojsa Duric, Peter John Littrup
Filed: 12 Dec 18
Utility
Waveform enhanced reflection and margin boundary characterization for ultrasound tomography
7 Jun 22
The present invention provides improved methods and systems for generating enhanced images of a volume of tissue.
Nebojsa Duric, Peter J. Littrup, Gursharan Singh Sandhu, Mark Krycia, Mark Sak
Filed: 18 Jun 19
Utility
System and Methods for Interactive Lesion Characterization
17 Mar 22
Described herein are systems, and methods for aiding a user to classify a volume of tissue.
Olivier Roy, Mark Forchette, Bruno Dacquay
Filed: 29 Nov 21
Utility
Method for representing tissue stiffness
19 Oct 21
A method and system for analyzing stiffness in a volume of tissue, the method including: emitting acoustic waveforms toward the volume of tissue with an array of ultrasound transmitters; detecting, with an array of ultrasound receivers, a set of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; generating, from the set of acoustic signals, a sound speed map and an acoustic attenuation map of a region of the volume of tissue, generating a stiffness map derived from combination of a set of sound speed parameter values of the sound speed map and a corresponding set of acoustic attenuation parameter values of the acoustic attenuation map, the stiffness map representing the distribution of the stiffness parameter across the region; and at a display in communication with the computer processor, rendering a stiffness image of the volume of tissue, based upon the stiffness map.
Nebojsa Duric, Peter Littrup, Cuiping Li, Olivier Roy, Steven Schmidt
Filed: 7 Nov 18
Utility
Tissue imaging and analysis using ultrasound waveform tomography
27 Jul 21
This application presents a system and related methods that analyze a volume of tissue using ultrasound waveform tomography imaging.
Gursharan Singh Sandhu, Nebojsa Duric, Cuiping Li, Olivier Roy, Erik West
Filed: 1 Mar 18
Utility
Patient interface system
20 Jul 21
A patient interface system for scanning a volume of tissue protruding from a patient, the system comprising: a base including a planar portion configured to support the patient in a prone configuration, and a frustoconical portion extending from the planar portion and defining a base aperture configured to receive the volume of tissue; and a support assembly configured to couple to the base, including a frame and a membrane retained in tension within the frame at a peripheral portion of the membrane, wherein the membrane defines a membrane aperture configured to align with the base aperture, and wherein the membrane is configured to deflect into the frustoconical portion of the base in response to the patient's weight.
James Szpak, Nebojsa Duric, Peter Littrup, Roman Janer, Mike Tesic
Filed: 9 Oct 18
Utility
System and Method for Feature Extraction and Classification on Ultrasound Tomography Images
4 Feb 21
Disclosed herein systems, processors, or computer-readable media configured with instructions to: receive transmission and/or reflection images of a tissue of a subject, wherein the images are generated from acoustic signals derived from acoustic waveforms transmitted through the tissue; provide a set of prognostic parameters associated with a user selected region of interest; wherein the set of prognostic parameters comprises sound propagation metrics characterizing sound propagation within a tissue; wherein the set of prognostic parameters corresponds to inputs into a tissue classifier model; wherein the set of prognostic parameters comprises a plurality of subsets of related feature groupings; and determine a type of tissue of the subject based on said plurality of subsets of related feature groupings using the classifier model, wherein the type of tissue is a cancerous tumor, a fibroadenoma, a cyst, a nonspecific benign mass, and an unidentifiable mass.
Majid MAHROOGHY, Gursharan Singh SANDHU, Peter LITTRUP
Filed: 21 Oct 20
Utility
System for shaping and positioning a tissue body
26 Jan 21
A tissue positioning system for contouring a patient tissue volume includes an axially displaceable interface having a surface configured to engage a breast or other tissue volume.
Ron Ho, Peter Littrup, Nebojsa Duric
Filed: 8 Feb 17
Utility
Ultrasound waveform tomography method and system
17 Aug 20
A method and system for generating an enhanced image of a volume of tissue, the method comprising: emitting acoustic waveforms toward the volume of tissue; detecting a set of acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating, from the set of acoustic signals, an initial model representing a distribution of an acoustomechanical parameter across a region of the volume of tissue; extracting a set of frequency components, from the set of acoustic signals; generating a first simulated wavefield with a first frequency component of the set of frequency components; generating an updated model of the initial model with the first simulated wavefield; iteratively refining the updated model with a set of simulated wavefields associated with the set of frequency components until a threshold condition is satisfied, thereby producing a final model; and generating the enhanced image from the final model of the volume of tissue.
Gursharan Singh Sandhu, Cuiping Li, Olivier Roy, Steven Schmidt, Nebojsa Duric
Filed: 3 Aug 15
Utility
System for Providing Scanning Medium
1 Jul 20
A system for providing scanning medium for scanning a volume of tissue comprising: an inner chamber that contains the scanning medium; a transducer mounted to the inner chamber and configured to move along a motion path, with the inner chamber, in scanning the volume of tissue; an outer chamber concentrically aligned about the inner chamber to guide the inner chamber along the motion path; a piston module defining a base surface within the inner chamber, the piston module comprising a medium inlet and a medium outlet for adjusting an amount of the scanning medium within the inner chamber; a detection subsystem coupled to the base surface of the piston module; and an actuator comprising a stationary portion mounted to the piston module and a moving portion coupled to the inner chamber and configured to produce motion of the inner chamber along the motion path.
Mike TESIC, Marc ORLOFF, Kevin OBRIGKEIT, David KUNZ, Roman JANER
Filed: 25 Feb 19
Utility
Waveform Enhanced Reflection and Margin Boundary Characterization for Ultrasound Tomography
22 Jan 20
The present invention provides improved methods and systems for generating enhanced images of a volume of tissue.
Nebojsa DURIC, Peter J. LITTRUP, Gursharan Singh SANDHU, Mark KRYCIA, Mark SAK
Filed: 17 Jun 19
Utility
Method of Characterizing the Pathological Response of Tissue to a Treatment Plan
15 Jan 20
A method of characterizing the pathological response of tissue to a treatment plan, including: obtaining a set of sequential morphology renderings of the tissue, wherein each rendering corresponds to a particular point in time during the treatment plan; generating a set of representative values of a biomechanical property of the tissue for the set of renderings, wherein each representative value is based on a corresponding rendering; determining a trend of the biomechanical property based on the set of representative values; and predicting response of the tissue to the treatment plan based on the trend of the biomechanical property.
Peter John Littrup, Nebojsa DURIC
Filed: 27 Mar 19
Utility
Method for Generating an Enhanced Image of a Volume of Tissue
15 Jan 20
A method and system for generating an enhanced image of a volume of tissue, comprising: emitting acoustic waveforms toward the volume of tissue; detecting acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating a reflection rendering of a region of the volume of tissue; generating at least one of a sound speed map and an attenuation map of the region of the volume of tissue; generating a transfer map derived from a set of sound speed parameter values of the sound speed map and/or a set of acoustic attenuation parameter values of the acoustic attenuation map, the set of sound speed parameter values and the set of acoustic attenuation parameters associated with the set of elements of the region of the volume of tissue; and rendering an enhanced image of the volume of tissue, derived from processing of the reflection rendering with the transfer map.
Nebojsa Duric, Peter LITTRUP, Cuiping LI
Filed: 28 Mar 19
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