19 patents
Utility
Dynamic Microvalve Protection Device
2 Dec 21
An endovascular system includes inner and outer catheters, a handle system operably coupled one end of the catheters, and a microvalve coupled to the other end of the catheters.
Leonard Pinchuk, James E. Chomas, John B. Martin, Aravind Arepally, Brett E. Naglreiter, Norman R. Weldon, Bryan M. Pinchuk
Filed: 23 Jun 21
Utility
Method of Delivering a Therapeutic Agent to a Solid Tumor for Treatment
4 Nov 21
A method for delivering a therapeutic agent to a tumor through a target vessel includes delivering the therapeutic agent through a lumen of a catheter which has been coated or otherwise structured to reduce the wall shear stress during delivery of the immunotherapy and by generating turbulent flow during the delivery of the therapeutic agent.
David Benjamin Jaroch, James E. Chomas
Filed: 14 Jul 21
Utility
Closed tip dynamic microvalve protection device
5 Oct 21
A method includes providing microvalve device having inner and outer catheters, and a filter valve attached to the distal end of the inner and outer catheters.
Bryan Pinchuk, James E. Chomas
Filed: 3 May 18
Utility
Method for infusing an immunotherapy agent to a solid tumor for treatment
17 Aug 21
A method for delivering an immunotherapy agent to a tumor includes advancing the delivery device into a vessel of a patient, and infusing the agent under pressure into the vessel to penetrate the tumor.
David Benjamin Jaroch, James E. Chomas
Filed: 13 Dec 18
Utility
Atraumatic Occlusive System with Compartment for Measurement of Vascular Pressure Change
5 Aug 21
A method of delivering a therapeutic agent into a patient vessel with a delivery device is provided.
Erik Dean Olson, David Benjamin Jaroch, Patrick Charles McCain, Aravind Arepally
Filed: 21 Apr 21
Utility
Therapeutic Treatment Device with Inverted Braided Vessel Occluder
22 Apr 21
An endovascular treatment device for use in a vessel during a therapy procedure includes a catheter and a vessel occluder coupled to the catheter.
Bryan Pinchuk, James E. Chomas, David Benjamin Jaroch
Filed: 9 Dec 20
Utility
Dynamic Microvalve Protection Device
6 Jan 21
An endovascular system includes inner and outer catheters, a handle system operably coupled one end of the catheters, and a microvalve coupled to the other end of the catheters.
James E. Chomas, Aravind Arepally, Bryan M. Pinchuk, Leonard Pinchuk
Filed: 20 Sep 20
Utility
Guiding Catheter Having Shape-retentive Distal End
16 Dec 20
A guiding catheter has a proximal portion constructed of a tubular braid and a shape-retentive distal portion including a superelastic hypotube cut to define particular mating, support, shape-retentive and flexibility characteristics.
David Benjamin Jaroch, Grayson Beck
Filed: 26 Aug 20
Utility
Atraumatic Occlusive System with Compartment for Measurement of Vascular Pressure Change
9 Dec 20
An atraumatic vessel occlusive system includes a flexible tubular member with an infusion lumen, a vessel occluder mounted at the distal end of the tubular member, and a pressure sensor located within a chamber defined by the occluder.
Erik Dean Olson, David Benjamin Jaroch, Patrick Charles McCain, Aravind Arepally
Filed: 3 Jun 19
Utility
Closed Tip Dynamic Microvalve Protection Device
28 Oct 20
A system includes a device having inner and outer catheters, and a filter valve attached to the distal end of the inner and outer catheters.
Bryan Pinchuk, James E. Chomas
Filed: 13 May 20
Utility
Dynamic microvalve protection device
26 Oct 20
An apparatus includes a delivery catheter having a deployable dynamic valve that dynamically opens and closes in response to relative fluid pressure thereabout, particularly while in an anatomical lumen.
James E. Chomas, Leonard Pinchuk, John Martin, Aravind Arepally, Brett E. Naglreiter, Bryan M. Pinchuk
Filed: 5 Nov 17
Utility
Guiding catheter having shape-retentive distal end
19 Oct 20
A guiding catheter has a proximal portion constructed of a tubular braid and a shape-retentive distal portion including a superelastic hypotube cut to define particular mating, support, shape-retentive and flexibility characteristics.
David Benjamin Jaroch
Filed: 7 Jan 18
Utility
System and method for selective pressure-controlled therapeutic delivery
21 Sep 20
A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element.
Aravind Arepally, David Benjamin Jaroch, Bryan Pinchuk, James E. Chomas
Filed: 12 Sep 17
Utility
Therapeutic Agent Delivery System with Delayed Activation
19 Aug 20
Systems with pressure-responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ.
David Benjamin Jaroch, James E. Chomas, Bryan Pinchuk, Aravind Arepally
Filed: 20 Feb 20
Utility
Dynamic Reconfigurable Microvalve Protection Device
10 Jun 20
An endovascular microvalve device for use in a vessel during a therapy procedure includes a catheter and a filter valve coupled to the catheters.
Bryan Pinchuk, James E. Chomas, David Benjamin Jaroch
Filed: 2 Feb 20
Utility
Implantable Dual Pathway Therapeutic Agent Delivery Port
8 Apr 20
A treatment system includes a dual lumen catheter system.
Aravind Arepally, James E. Chomas, Patrick Charles McCain, David Benjamin Jaroch, Jennifer D. Lucky
Filed: 6 May 19
Utility
Dynamic reconfigurable microvalve protection device
16 Mar 20
An endovascular microvalve device for use in a vessel during a therapy procedure includes a catheter and a filter valve coupled to the catheters.
Bryan Pinchuk, James E. Chomas, David Benjamin Jaroch
Filed: 19 Mar 17
Utility
Systems and Methods for Pressure-Facilitated Therapeutic Agent Delivery
5 Feb 20
A therapeutic agent delivery system includes a catheter, a vascular occluder, a pressure sensor system, and a pump system.
James E. Chomas, Aravind Arepally, David Benjamin Jaroch, Mike Bojanowski
Filed: 8 May 19
Utility
Injection Port for Therapeutic Delivery
2 Oct 19
A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element.
David Benjamin Jaroch, James E. Chomas, Bryan Pinchuk, Aravind Arepally
Filed: 14 Jan 18
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