6 patents
Utility
Inclusion Complexes of Pharmaceuticals and Cyclic Oligomers
22 Dec 22
Pharmaceutical formulations including an inclusion complex of an API with a cyclic oligomer, and methods of forming such pharmaceutical formulations are described.
Robert O. WILLIAMS, III, Urvi GALA, Dave MILLER, Angela SPANGENBERG, Daniel J. ELLENBERGER
Filed: 24 Sep 20
Utility
Abiraterone-cyclic Oligomer Pharmaceutical Formulations and Methods of Formation and Administration Thereof
17 Nov 22
The present disclosure relates to pharmaceutical formulations including abiraterone and a cyclic oligomer, as well as tablets including such pharmaceutical formulations, methods of forming such pharmaceutical formulations, and methods of administering such pharmaceutical formulations or tablets.
Dave MILLER, Urvi GALA, Robert O. WILLIAMS, III, Angela SPANGENBERG
Filed: 17 Mar 20
Utility
Weakly Basic Drug and Ionic Polymer Pharmaceutical Formulations and Methods of Formation and Administration Thereof
6 May 21
The present disclosure relates to pharmaceutical formulations including a weakly basic drug and an ionic polymer in an amorphous solid dispersion, as well as methods of forming such pharmaceutical formulations, and methods of administering such pharmaceutical formulations.
Robert O. WILLIAMS, III, Scott V. JERMAIN, Daniel Alan DAVIS, Dave A. MILLER
Filed: 8 Oct 20
Utility
SUBSTITUTED 3-ISOBUTYL-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-a]ISOQUINOLIN-2-OL COMPOUNDS, THEIR SYNTHESIS, AND USE THEREOF
25 Mar 21
The invention relates to substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol compounds, their synthesis, pharmaceutical compositions containing them, and methods of using them in the treatment of disorders benefiting from inhibition of vesicular monoamine transporter 2 (VMAT2).
Dave Alan MILLER, Daniel J. ELLENBERGER, Esmir GUNIC, Jean-Luc GIRARDET, Angela SPANGENBERG
Filed: 4 Dec 20
Utility
Thermo-kinetic Mixing for Pharmaceutical Applications
19 Aug 20
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite.
Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
Filed: 4 May 20
Utility
Improved Drug Formulations
8 Jan 20
The disclosure provides for improved pharmaceutical compositions containing an active pharmaceutical ingredient and a non-polymeric lubricant and methods of manufacturing the same.
Dave A. MILLER, Daniel J. ELLENBERGER, Sandra U. SCHILLING
Filed: 7 May 17
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