169 patents
Page 4 of 9
Utility
Effective vaccination against porcine reproductive and respiratory syndrome (PRRS) virus prior to weaning
7 Jun 22
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components.
Jay Gregory Calvert, Robert G. Ankenbauer, Jacqueline Gayle Marx, Douglas S. Pearce, Marcia L. Keith
Filed: 18 Mar 20
Utility
Antimicrobial peptides and methods of using same
7 Jun 22
Antimicrobial peptides of general formula X0X1X2C X3X4X5CX6X7X8X9CYX10X11CX12X13 are provided.
Michael Kuhn, Christopher A. Zook, Derek James Sheehan, Eric Baima, Richard Andrew Ewin, Hilary Phelps
Filed: 5 Dec 18
Utility
Serotonin 5-HT2B Inhibitory Compounds
26 May 22
The compounds of the invention, as described herein, are novel serotonin 5-HT2B antagonists useful for the treatment of myxomatous mitral valve degeneration (MMVD), congestive heart failure (CHF), and/or asymptomatic heart failure in animals, preferably canine.
Richard Andrew Ewin, Govindan Subramanian, Jinxia (Nancy) Deng
Filed: 26 Mar 20
Utility
Vaccination system for delivering vaccine to avian pullets, and associated methods, devices, and assemblies
24 May 22
A vaccination system for delivering a vaccine substance to avian pullets is provided.
William Douglas Samson
Filed: 7 May 19
Utility
Endoparasitic depsipeptides
17 May 22
Michael P. Curtis, Susan M. Sheehan, Graham M. Kyne, Matthew W. Bedore, Richard A. Ewin, Paul D. Johnson, Tom L. McTier, Christoper S. Knauer, Rajendran Vairagoundar
Filed: 28 Nov 18
Utility
Internal Teat Sealants and Their Use In the Prevention of Bovine Mastitis In the Dry Cowb
5 May 22
An intramammary syringe contains a seal formulation for forming a physical barrier in the teat canal of a non-human animal.
Brendan Gerard Smith
Filed: 20 Dec 21
Utility
Multivalent Live-attenuated Influenza Vaccine for Prevention and Control of Equine Influenza Virus (EIV) in Horses
5 May 22
The present invention provides compositions and methods related to equine live-attenuated influenza vaccines.
Luis Martinez-Sobrido, Thomas Chambers, Kendall Wayne King
Filed: 27 Feb 20
Utility
Methods and compositions for induction of immune response
3 May 22
The invention provides a substantially antigen-free composition for induction of innate immune response in a bird or a mammal, the composition comprising a saponin, a sterol, a quaternary amine, and a polyacrylic polymer to the mammal or bird.
Paul Joseph Dominowski, Duncan Mwangi, Joseph M. Bricker, Dennis L. Foss, Sharath K. Rai, Suman Mahan
Filed: 21 Nov 14
Utility
Ready-to-use Injectable Formulations
28 Apr 22
The invention describes a ready-to-use injectable cephalosporin composition with reasonable viscosity, resuspendability, and syringeability attributes for injection as an antibiotic for animals.
Vijaya Bharti Joshi, Laibin Luo, Todd P. Foster
Filed: 5 Mar 20
Utility
INTERLEUKIN-31 Monoclonal Antibodies for Veterinary Use
28 Apr 22
A monoclonal antibody, or antigen-binding portion thereof is provided that specifically binds to a region on a mammalian IL-31 protein involved with interaction of the IL-31 protein with its co-receptor, wherein the binding of said antibody to said region is impacted by mutations in a 15H05 epitope binding region selected from: a region between about amino acid residues 124 and 135 of a feline IL-31 sequence represented by SEQ ID NO: 157 (Feline_IL31_wildtype); a region between about amino acid residues 124 and 135 of a canine IL-31 sequence represented by SEQ ID NO: 155 (Canine_IL31); and a region between about amino acid residues 118 and 129 of an equine IL-31 sequence represented by SEQ ID NO: 165 (Equine_IL31).
Gary Francis Bammert, Steven Alan Dunham, Sebastian C. J. Steiniger
Filed: 7 Jan 22
Utility
Anti-tgfb Antibodies and Therapeutic Uses Thereof
21 Apr 22
The present disclosure encompasses novel anti-TGFβ antibodies, antigen binding proteins and polynucleotides encoding the same.
Lisa Marie BERGERON, Gary F. Bammert, Henry Luis Campos, Sandra Ann Marie Lightle, Catherine J. Strietzel
Filed: 7 Jun 21
Utility
Fish Handling Apparatus and Associated Method
24 Mar 22
A fish handling apparatus comprises a supply arrangement arranged to supply a plurality of fish and a receiving arrangement arranged to receive and distribute a single fish of the plurality of fish.
Johan Odd Moflag
Filed: 23 Sep 21
Utility
Foot-and-mouth Disease Vaccine
24 Mar 22
Compositions for prevention of Foot and Mouth Disease (FMD) are provided, comprising an antigen component in the amount equivalent to 0.5-20 μg FMD virus and an adjuvant component comprising oil, an immunostimulatory oligonucleotide, and a polycationic carrier.
Paul Joseph Dominowski, John Morgan Hardham, James Alan Jackson, Cyril Gerard Gay, Luis Leandro Rodriguez, Peter William Krug, Aida Elizabeth Rieder
Filed: 19 Feb 21
Utility
Signal Amplification In Solution-based Plasmonic Specific-binding Partner Assays
17 Mar 22
The present invention relates to analyte detection devices and methods of using such devices to detect minute quantities of a target analyte in a sample.
Rajesh K. MEHRA, Vincent CHIANG, Kenneth ARON, Jessica FRISZ
Filed: 29 Nov 21
Utility
Anthelmintic Laboratory Animal Model for Heartworm
10 Mar 22
The current invention describes a laboratory animal model for dirofilarial nematodes wherein said laboratory animal is fed a dietary admixture of laboratory feed containing an immunosuppressing agent, for example, a glucocorticoid.
Brian John Mills, Tom L. McTier, Christopher S. Knauer, Debra Jean Woods
Filed: 7 Jan 20
Utility
Signal Amplification In Plasmonic Specific-binding Partner Assays
10 Mar 22
The present invention relates to analyte detection devices and methods of using such devices to detect minute quantities of a target analyte in a sample.
Rajesh K. Mehra, Vincent Chiang, Kenneth P. Aron, Asher Krell
Filed: 16 Nov 21
Utility
Palatable Formulations
3 Mar 22
The present invention is directed to a soft chewable composition comprising or containing a therapeutically effective amount of a veterinary active agent, preferably a JAK inhibitor; an animal based palatant, a non-animal based palatant, a flavor modifier, and at least one veterinary acceptable excipient that is selected from at least one each of a disintegrant, binder, lubricant, humectant, and glidant; and wherein the soft chewable tablet is compressed with a rotary tablet press; and methods for treating or preventing cancer, asthma, atopic dermatitis, autoimmune disorders, pruritus associated with allergic dermatitis, allergies, and chronic respiratory disease in an animal.
Paramjit Singh, Debendra Kumar Panda, Jeffrey Ellis Price, Atul Chhagan Badhan, Nicholas Finn Cunningham
Filed: 19 Feb 20
Utility
Signal amplification in lateral flow and related immunoassays
22 Feb 22
The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample.
Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
Filed: 20 Mar 19
Utility
Lateral Flow Device for Detecting SARS-CoV-2 Antibodies in Human and Animal Samples
17 Feb 22
The invention provides a lateral flow device and methods for the detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a sample of bodily fluid of an animal or human.
Joshua T. Lizer, Jason J. Workman, James P. Gillies, Eric T. Baima, Rajesh K. Mehra
Filed: 30 Jul 21
Utility
Anti-coronavirus Vaccines
17 Feb 22
The invention provides stable coronavirus spike proteins.
Eric Todd Baima, Yulia Burakova, Paul Joseph Dominowski, Steven Alan Dunham, Nicole Lynn Hainer, John Morgan Hardham, Mahesh Kumar, Jason John Millership, Duncan M. Mwangi, Sharath K. Rai, Sharon Marie Wappel, Dennis Lee Foss
Filed: 30 Jul 21