63 patents
Page 4 of 4
Utility
Combination Therapy for Treatment of Cancer
23 Oct 19
Compositions, combinations and methods comprising a CDK4/6 inhibitor of Formula D with a selective estrogen receptor downregulator of Formula A, B or C that are advantageous for the treatment of abnormal cellular proliferation, including a cancer or a tumor.
JAY C. STRUM, Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Debra A. Tonetti
Filed: 1 Jul 19
Utility
Preservation of Immune Response During Chemotherapy Regimens
23 Oct 19
The addition of a selective, fast-acting, short half-life CDK 4/6 inhibitor in a very specific dosage regimen to the combination of chemotherapy with a checkpoint inhibitor provides superior results in the treatment of a tumor or cancer.
Jessica A. Sorrentino, Ann Y. Lai, Jay C. Strum, Patrick Joseph Roberts
Filed: 4 Jun 19
Utility
HSPC-sparing treatments for Rb-positive abnormal cellular proliferation
7 Oct 19
This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy Hematopoietic Stem Cells and Progenitor Cells (HSPCs), associated with current treatment modalities.
Jay Copeland Strum, John Emerson Bisi, Patrick Joseph Roberts, Francis Xavier Tavares
Filed: 23 Aug 18