77 patents
Utility
Devices And Methods For Engaging Indexed Valve And Pressurized Canister Assembly With Collar And For Linear Actuation By Plunger Assembly Into Fluid Communication With Device For Regulating Drug Delivery
18 Jan 24
A valve assembly comprising a housing and a valve, the valve being disposed within the housing, a first indexed member integral to the housing, the first indexed member adapted to be complementary to a second indexed member, and a radio frequency identification device adapted to communicate with a radio frequency receiver, the valve being configured to align with a canister, seal the canister and open in a single movement.
Frederick J. Montgomery, Duncan P. Bathe, Daniel J. Lee, Scott I. Biba, Todd J. Bakken
Filed: 15 Sep 23
Utility
Apparatus and Method for Detecting Liquid Level In a Clear or Partially Clear Container
9 Nov 23
A trap bowl is provided to accumulate liquid droplets from a filter, as a liquid content.
Scott I. Biba
Filed: 19 Jul 23
Utility
Systems and Methods for Delivery of Therapeutic Gas
31 Aug 23
A therapeutic gas delivery system with at least one gas supply subsystem is disclosed.
Jaron M. Acker, Jeff Milsap, Robin Roehl, Jeffrey Schmidt, Craig R. Tolmie
Filed: 14 Feb 23
Utility
Methods Of Administering High Concentrations Of Nitric Oxide
17 Aug 23
Described are methods of administering therapeutic gases comprising high concentrations of nitric oxide, particularly concentrations above 2,000 ppm.
Brahm Goldstein, Douglas Stuart Greene
Filed: 19 Apr 23
Utility
Systems and Methods for Intelligent Gas Source Management
20 Jul 23
A therapeutic gas source and cart and methods thereof for use with a therapeutic gas delivery system is disclosed.
Jaron Matthew Acker, Craig R. Tolmie, Jeffrey Martin Schmidt, Brian McCormack, Conor Briody
Filed: 14 Feb 23
Utility
Uses of Ornithine Phenylacetate for Treating Hyperammonemia
29 Jun 23
Embodiments of the present disclosure relate to doses of ornithine phenylacetate for treating or ameliorating hyperammonemia and the methods of administrating the same in a patient with a chronic liver disease, for example, cirrhosis.
Regis Vilchez
Filed: 17 May 21
Utility
Systems and Method for Delivery of Therapeutic Gas to Patients, In Need Thereof, Receiving Breathing Gas from a Ventilator That Varies at Least Pressure And/or Flow Using Enhanced Therapeutic Gas (No) Flow Measurement
29 Jun 23
The present disclosure generally relates to systems and methods for delivery of therapeutic gas to patients, in need thereof, receiving breathing gas from a high frequency ventilator using at least enhanced therapeutic gas (e.g., nitric oxide, NO, etc.) flow measurement.
Jaron M. Acker, Craig R. Tolmie
Filed: 6 Mar 23
Utility
Methods and Compositions for Improving Kidney Function In Patients with Hepatorenal Syndrome
27 Apr 23
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease.
Khurram Jamil, Stephen Chris Pappas, Peter Teuber
Filed: 28 Oct 22
Utility
Systems and Methods for Manufacturing and Safety of an NO2-TO-NO Reactor Cartridge Used to Deliver No for Inhalation Therapy to a Patient
20 Apr 23
The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy.
Jaron M. Acker, Thomas Kohlmann
Filed: 19 Dec 22
Utility
Apparatus and Method for Detecting Liquid Level In a Clear or Partially Clear Container
20 Apr 23
A trap bowl is provided to accumulate liquid droplets from a filter, as a liquid content.
Scott I. Biba
Filed: 15 Dec 22
Utility
Methods and Compositions for Improving Kidney Function In Patients with Hepatorenal Syndrome
6 Apr 23
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease.
Khurram Jamil, Stephen Chris Pappas, Peter Teuber
Filed: 28 Oct 22
Utility
Extended Release, Abuse Deterrent Dosage Forms
16 Mar 23
Extended release, abuse deterrent dosage forms comprising crush-resistant controlled-release particles that provide abuse deterrent properties to the dosage forms.
Jonathan Gaik, Jaehan Park, Ryan Lathrop, Gary Nichols, John Schallom
Filed: 16 Sep 22
Utility
Systems and Methods for Delivery of Therapeutic Gas
9 Mar 23
Therapy gas delivery systems that provide run-time-to-empty information to a user of the system and methods for administering therapeutic gas to a patient.
Jaron M. Acker, Jeff Milsap, Robin Roehl, Jeffrey Schmidt, Craig R. Tolmie
Filed: 10 Nov 22
Utility
Preparation of Sufentanil Citrate and Sufentanil Base
9 Mar 23
Provided herein are processes for forming sufentanil citrate from sufentanil base.
George Helmut Klemm, Brian Orr, Joel McClenaghan
Filed: 8 Nov 22
Utility
Methods and Compositions for Improving Kidney Function In Patients with Hepatorenal Syndrome
23 Feb 23
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease.
Khurram Jamil, Stephen Chris Pappas, Peter Teuber
Filed: 28 Oct 22
Utility
Methods of Using Inhaled Nitric Oxide Gas for Treatment of Acute Respiratory Distress Syndrome In Children
2 Feb 23
Described herein is a treatment of acute respiratory distress syndrome (ARDS) using incremental dosing of nitric oxide.
Jim Potenziano, Ronald Bronicki
Filed: 15 Jul 22
Utility
Method for Generating Immunoregulatory Cells In a Blood-derived Sample
26 Jan 23
The present invention relates to a method comprising the steps of provision of a sample derived from a blood sample of a subject that has received a checkpoint-inhibitor therapy and is suspected of developing or has developed symptoms of immune-related adverse events (irAE), adding a photosensitizing agent to the sample, and subjecting the sample to irradiation, which preferably generates immunoregulatory NK cells in said sample.
Robert Zeiser, Petya Apostolova, Justus Duyster
Filed: 17 Dec 20
Utility
Method of Identifying and Treating Premature Infants at Risk for BPD
5 Jan 23
Methods for identifying premature infants at risk for developing bronchopulmonary dysplasia and/or most likely to benefit from administration of inhaled nitric oxide for prevention of bronchopulmonary dysplasia (BPD).
Douglas Stuart Greene, Joseph J. Medicis, Jim Potenziano
Filed: 12 Sep 22
Utility
Dosages and Uses of Ornithine Phenylacetate for Treating Hyperammonemia
17 Nov 22
Embodiments of the present disclosure relate to doses of ornithine phenylacetate for treating or ameliorating hyperammonemia and the methods of administrating the same in a patient with a chronic liver disease, for example, cirrhosis.
Xiaofeng Wang Rears, Jack Tseng, Carmen Mak, Nagaraju Poola, Regis Vilchez, Aniruddha Potnis, Susan VanMeter, Jan Stange
Filed: 15 Oct 20
Utility
Administration and Monitoring of Nitric Oxide In Ex Vivo Fluids
10 Nov 22
Described are systems and methods for monitoring administration of nitric oxide (NO) to ex vivo fluids.
Jim Potenziano, Douglas R. Hansell, Jeff Griebel, Eddie Costa, Lisa Cooper, David William Newman
Filed: 13 Jul 22