126 patents
Page 7 of 7
Utility
Methods for Multi-resolution Analysis of Cell-free Nucleic Acids
8 Jan 20
The present disclosure provides a method for enriching for multiple genomic regions using a first bait set that selectively hybridizes to a first set of genomic regions of a nucleic acid sample and a second bait set that selectively hybridizes to a second set of genomic regions of the nucleic acid sample.
Marcin SIKORA
Filed: 28 Sep 17
Utility
Methods and Systems for Analyzing Nucleic Acid Molecules
25 Dec 19
The disclosure provides methods for processing nucleic acid populations containing different forms (e.g., RNA and DNA, single-stranded or double-stranded) and/or extents of modification (e.g., cytosine methylation, association with proteins).
Andrew KENNEDY, Stefanie Ann Ward MORTIMER, Helmy ELTOUKHY, AmirAli TALASAZ, Diana ABDUEVA, Matthew SCHULTZ
Filed: 23 Jun 19
Utility
METHODS AND SYSTEMS FOR DETERMINING The CELLULAR ORIGIN OF CELL-FREE NUCLEIC ACIDS
18 Dec 19
Provided herein are methods that are useful in determining the cellular origin of cell-free nucleic acid (cfNA) fragments from cfNA samples, such as liquid biopsy samples.
Ariel JAIMOVICH, Andrew KENNEDY, Justin I. ODEGAARD
Filed: 2 Jun 19
Utility
Methods and Systems for Detecting Insertions and Deletions
4 Dec 19
Methods and systems for improving callings of insertions and/or deletions by identifying genetic sequence reads having identical molecular barcodes and sequences among sequence reads from a nucleic acid sequencer, grouping the genetic reads into a family, and processing families comprising split reads to detect the insertion and/ or deletion in a sample of polynucleotide molecules.
Marcin SIKORA, Mohammad R. MOKHTARI, Darya CHUDOVA
Filed: 12 Aug 19
Utility
Methods for Fragmentome Profiling of Cell-free Nucleic Acids
20 Nov 19
The present disclosure contemplates various uses of cell-free DNA.
DIANA ABDUEVA
Filed: 9 Jan 19
Utility
Systems and Methods to Detect Rare Mutations and Copy Number Variation
16 Oct 19
The present disclosure provides a system and method for the detection of rare mutations and copy number variations in cell free polynucleotides.
AmirAli TALASAZ, HELMY ELTOUKHY, Stefanie Ann Ward MORTIMER
Filed: 18 Apr 19