55 patents
Page 3 of 3
Utility
Pharmaceutical soft gelatin capsule dosage form with modified guar gum
17 Aug 20
A pharmaceutical soft gelatin capsule dosage form that includes (a) a shell that includes gelatin; and (b) a fill that includes at least one active ingredient, one or more polyethylene glycol, and a modified guar gum.
Brendan Muldoon, Ryan Gerald Loughlin, Gerarde Sweeney, Emma Karen Boyd
Filed: 17 Oct 17
Utility
Formation of bone
10 Aug 20
Compositions and methods for inducing or promoting repair of a bone fracture.
Fariba Dehghani, Ali Fathi, Suzanne Marie Mithieux, Anthony Steven Weiss
Filed: 31 Aug 16
Utility
Thread insertion devices
13 Jul 20
Devices and methods for inserting an implant into skin or other tissue of a patient can include a hyaluronic thread coupled with an insertion device that can provide a supportive enclosure for the thread as it is injected into a patient's skin or other tissue.
Antoine Duc, Bastien Mandaroux
Filed: 23 Jan 17
Utility
Stable formulations of linaclotide
6 Jul 20
The present invention relates to stable pharmaceutical compositions comprising linaclotide or pharmaceutically acceptable salts thereof, as well as to various methods and processes for the preparation and use of the compositions.
Yun Mo, Angelika Fretzen, Brian Cali, Mahendra Dedhiya
Filed: 16 Jan 19
Utility
Gene silencing in skin using self-delivery siRNA delivered by a meso device
29 Jun 20
The present invention is drawn to a low-cost “meso” device that is able to effectively deliver functional self-delivery siRNA to subject and inhibit expression of a gene in the subject as well as related methods.
Roger L. Kaspar, Tycho Speaker
Filed: 2 Aug 17
Utility
5-aminosalicylic acid capsule formulation
22 Jun 20
A dosage form comprising a capsule containing one or more tablets of 5-aminosalicylic acid or a salt thereof as an active ingredient where each of the one or more tablets is enterically coated is disclosed.
Emma Boyd, Deborah Leigh Caldwell, Catherine Coulter, Ryan Loughlin, Stephen McCullagh
Filed: 10 Mar 19
Utility
Stable formulations of linaclotide
8 Jun 20
The present invention relates to stable pharmaceutical compositions comprising linaclotide or pharmaceutically acceptable salts thereof, as well as to various methods and processes for the preparation and use of the compositions.
Yun Mo, Angelika Fretzen, Brian Cali, Mahendra Dedhiya
Filed: 25 Sep 19
Utility
Modified release formulations of memantine oral dosage forms
25 May 20
The present invention provides pharmaceutical compositions given once daily containing at least one therapeutically active ingredient selected from the group consisting of memantine and a pharmaceutically acceptable salt of memantine, and a pharmaceutically acceptable polymeric matrix carrier.
Suneel K Rastogi, Niranjan Rao, Antonia Periclou, Wattanaporn Abramowitz, Mahendra G Dedhiya, Shashank Mahashabde
Filed: 19 Jul 16
Utility
Preparation and/or formulation of proteins cross-linked with polysaccharides
18 May 20
Therapeutic compositions and/or formulations are provided, comprising: at least one cross-linked protein matrix, wherein the at least one cross-linked protein matrix comprises at least one protein residue and at least one saccharide-containing residue, and methods of producing the same.
Jens Sommer-Knudsen
Filed: 5 Dec 16
Utility
Injectable monophase hydrogels
18 May 20
An injectable monophase hydrogel is provided that is made of a reaction mixture of hyaluronic acids having different molecular weights.
Pierre F. Lebreton
Filed: 19 Sep 18
Utility
Preparation of bile acids and intermediates thereof
27 Apr 20
Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
Filed: 30 Jul 18
Utility
Thread insertion devices
23 Mar 20
Devices and methods for inserting an implant into skin or other tissue of a patient can include an insertion device that can enclose and support a hyaluronic thread as it is injected into a patient's skin or other tissue.
Antoine Duc, Bastien Mandaroux
Filed: 23 Jan 17
Utility
Processes for making cyclic lipid implants for intraocular use
14 Oct 19
Biocompatible implants comprising a cyclic lipid therapeutic agent are made using a low temperature melt extrusion process.
Lon T. Spada, James N. Chang, Michelle H. Luu
Filed: 5 Oct 15
Utility
Use of agonists of formyl peptide receptor 2 for treating dermatological diseases
7 Oct 19
The present invention relates to a method for treating dermal inflammation and dermal diseases by local or systemic delivery, in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of Formyl peptide receptor 2 (FPR2).
Veena Viswanath, Richard L. Beard, John E. Donello, Edward Hsia
Filed: 17 Apr 17
Utility
Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
7 Oct 19
Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers.
Xiaojie Yu, Nicholas J. Manesis, Jacob Pollock
Filed: 8 Oct 17