6 patents
Utility
Antagonistic Peptide Targeting IL-2, IL-9, and IL-15 Signaling for the Treatment of Cytokinerelease Syndrome and Cytokine Storm Associated Disorders
26 Oct 23
The yc-family Interleukin-2 (IL-2), Interleukin-9 (IL-9), and Interleukin-15 (IL-15) cytokines are associated with important human diseases, such as cytokine-release syndrome and cytokine storm associated disorders.
Yutaka Tagaya, Nazli Azimi
Filed: 22 Jun 21
Utility
Modulating Gamma-c-cytokine Activity
2 Mar 23
Embodiments relate to peptide antagonists of γc-family cytokines, which is associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (GvHD).
Nazli Azimi
Filed: 18 Jul 22
Utility
Stable Modulators of Gamma-c-cytokine Activity
21 Oct 21
Disclosed herein are stable peptide antagonists based on the consensus yc-subunit binding site to inhibit the activity of yc-cytokines.
Nicholas Doerr, Laith Q. Al-Mawsawi, Nazli Azimi
Filed: 4 Apr 18
Utility
Selective Peptide Antagonists
18 Mar 21
Methods and compositions related to the selective, specific disruption of multiple ligand-receptor signaling interactions, such as ligand-receptor interactions implicated in disease, are disclosed.
Nazli Azimi, Yutaka Tagaya
Filed: 28 Oct 20
Utility
Peptide Conjugates
23 Dec 20
Methods and compositions related to the selective, specific disruption of multiple ligand-receptor signaling interactions, such as ligand-receptor interactions implicated in disease, are disclosed.
Yutaka Tagaya, Nazli Azimi
Filed: 3 Sep 20
Utility
Modulating the Effects of Gamma-c-cytokine Signaling for the Treatment of Alopecia and Alopecia Associated Disorders
4 Nov 20
The γc-family cytokines, Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), Interleukin-15 (IL-15), and Interleukin-21 (IL-21), are associated with important human diseases, such as alopecia and alopecia associated disorders.
Yutaka Tagaya, Nazli Azimi
Filed: 29 Apr 20
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