14 patents
Utility
Biomarkers for CD47 Blockade Therapy
15 Sep 22
Subjects responsive to a CD47 blocking agent, such as SIRPαFc, exhibit an elevated level of expression of one or more markers.
Lisa Danae Schultz Johnson, Mithunah Krishnamoorthy, Sandra Lauren Blitz
Filed: 28 Nov 19
Utility
CD47 Blockade with Parp Inhibition for Disease Treatment
14 Oct 21
CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and poly-(ADP-ribose) polymerase (PARP) inhibitor.
Lisa Danae Schultz Johnson, Lei Cui
Filed: 29 Aug 19
Utility
CD47 Blockade with Radiation Therapy
12 Aug 21
This patent application relates to the treatment of cancer and other diseases that have a CD47+ phenotype.
Lei Cui, Lisa Danae Schultz Johnson
Filed: 5 Nov 18
Utility
Treatment of CD47+ Disease Cells with Sirp Alpha-fc Fusions
8 Jul 21
CD47+ disease cells, such as CD47+ cancer cells, are treated with an agent that blocks signalling via the SIRPα/CD47 axis.
Robert Adam Uger, Penka Slavtcheva Slavova-Petrova, Xinli Pang
Filed: 23 Dec 20
Utility
Improvements In CD47 Blockade Therapy by Egfr Antibody
11 Feb 21
CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and an EGFR antibody such as cetuximab.
Gloria Hoi Ying LIN, Natasja Nielsen VILLER, Mark Michael WONG, Robert Adam UGER
Filed: 8 Mar 19
Utility
CD47 Blockade Therapy with CD38 Antibody
11 Feb 21
CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and a CD38 antibody such as daratumumab.
Gloria Hoi Ying LIN, Natasja Nielsen VILLER, Mark Michael WONG, Jeffrey Todd WINSTON, Robert Adam UGER
Filed: 8 Mar 19
Utility
Treatment of CD47+ disease cells with SIRPĪ±-Fc fusions
2 Feb 21
CD47+ disease cells, such as CD47+ cancer cells, are treated with an agent that blocks signalling via the SIRPα/CD47 axis.
Robert Adam Uger, Penka Slavtcheva Slavova-Petrova, Xinli Pang
Filed: 25 Apr 18
Utility
Fluorinated imidazo[4,5-C]quinoline derivatives as inhibitors of bromodomain containing proteins
29 Jun 20
Abdelmalik Slassi, Peter Dove
Filed: 10 Mar 19
Utility
Fluorinated Amide Derivatives and Their Uses As Therapeutic Agents
10 Jun 20
Abdelmalik Slassi
Filed: 11 Feb 20
Utility
CD47 Blockade Therapy
20 May 20
CD47+ disease cells, such as various cancers, are treated using a combination of CD47 blockade with T cell checkpoint inhibition.
Gloria Hoi Ying LIN, Natasja Nielsen VILLER, Lisa Danae Schultz JOHNSON, Mark Michael WONG, Robert Adam UGER
Filed: 26 Mar 18
Utility
Fluorinated amide derivatives and their uses as therapeutic agents
30 Mar 20
Abdelmalik Slassi
Filed: 30 Oct 16
Utility
Heteroaromatic-fused Imidazolyl Amides, Compositions and Uses Thereof As Sting Agonists
29 Jan 20
Abdelmalik Slassi, Peter DOVE, Zezhou WANG, Hoi Ying LIN, David Alexander ROSA, Jeffrey Todd WINSTON
Filed: 3 Oct 19
Utility
Heterocycle Derivatives and Their Use for the Treatment of CNS Disorders
4 Dec 19
Abdelmalik Slassi
Filed: 15 Aug 19
Utility
Heterocycle derivatives and their use for the treatment of CNS disorders
30 Sep 19
Abdelmalik Slassi
Filed: 30 Oct 16
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