12 patents
Utility
Crystallized Oxalate Decarboxylase and Methods of Use
22 Dec 22
Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed.
Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
Filed: 18 Nov 21
Utility
Methods of Treating Hyperoxaluria
1 Dec 22
Disclosed are methods and compositions which can be used to treat diseases or disorders associated with an elevated amount of oxalate, including, for example, hyperoxaluria, in particular enteric hyperoxaluria.
Danica Grujic, Kristine E. Bernard, Annamaria T. Kausz, Zhiqun Zhang
Filed: 6 Nov 20
Utility
Crystallized Oxalate Decarboxylase and Methods of Use
5 May 22
Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed.
Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
Filed: 17 Jun 21
Utility
Crystallized oxalate decarboxylase and methods of use
28 Dec 21
Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed.
Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
Filed: 14 Jan 20
Utility
Compositions, methods, and devices for dialysis
3 Aug 21
Compositions of peritoneal dialysis solutions and metabolizing enzymes, and their uses to treat disorders associated with elevated levels of metabolites are disclosed.
Alexey Margolin, Danica Grujic, Stefan Pierzynowski
Filed: 6 Jun 14
Utility
Recombinant uricase enzyme
26 Oct 20
Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.
Aditi R. Deshpande, Danica Grujic, Sridhar Govindarajan, Mark Welch
Filed: 4 Nov 19
Utility
Recombinant Uricase Enzyme
30 Sep 20
Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.
Aditi R. DESHPANDE, Danica GRUJIC, Sridhar GOVINDARAJAN, Mark WELCH
Filed: 5 Jul 18
Utility
Crystallized Oxalate Decarboxylase and Methods of Use
29 Apr 20
Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed.
Bhami C. Shenoy, Teresa G. Cachero, John Shin, Lekai Zhang, Aftab Rashid, Danica Grujic, Reena J. Patel, Margaret Ellen McGrath
Filed: 18 Jun 19
Utility
Crystallized Oxalate Decarboxylase and Methods of Use
29 Apr 20
Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed.
Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
Filed: 13 Jan 20
Utility
Recombinant Uricase Enzyme
4 Mar 20
Disclosed are recombinant mutant Candida utilis uricase enzymes with improved pancreatin stability and/or activity, compositions containing such uricase enzymes, which can be used, among other things, to treat diseases or disorders associated with an elevated amount of uric acid, including, for example, hyperuricemia, hyperuricosuria, and gout.
Aditi R. Deshpande, Danica Grujic, Sridhar Govindarajan, Mark Welch
Filed: 4 Nov 19
Utility
Crystallized oxalate decarboxylase and methods of use
24 Feb 20
Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed.
Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
Filed: 13 Feb 19
Utility
Crystallized Oxalate Decarboxylase and Methods of Use
22 Jan 20
Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed.
Jack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
Filed: 13 Feb 19
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