AZTherapies USPTO patents

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Powdered Formulations of Cromolyn Sodium and Ibuprofen

10 Aug 23

The invention is directed to a composition comprising cromolyn sodium and ibuprofen, wherein the cromolyn sodium is micronized and the cromolyn sodium and ibuprofen are present in a weight ratio of 1:1-2.

David R. Elmaleh, Juan B. Gonzalez

Filed: 7 Sep 22

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CAR-Treg-Based Therapies Targeting Myelin Oligodendrocyte Glycoprotein (MOG) for Treating Neurodegenerative Diseases

6 Jul 23

The invention provides compositions and methods for suppressing autoimmune components of neurodegenerative diseases and thereby providing therapeutic effects to patients suffering from such diseases, Compositions and methods include immunosuppressive moieties such as regulatory T cells (Tregs) and proteins expressed by Tregs coupled to a chimeric antigen receptor or protein that specifically binds one or more glial cell markers.

Levi B. Watkin, Philip G. Ashton-Rickardt

Filed: 28 May 21

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6 Jul 23

The invention provides compositions and methods for reducing the immunogenicity of cells for transplant including cell-based immunotherapies.

Philip G. Ashton-Rickardt

Filed: 23 Apr 21

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14 Jul 22

David R. Elmaleh, Rudolph E. Tanzi, Ana Griciuc, Robert Warren, Karen Reeves

Filed: 5 Sep 19

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5 Apr 22

The present disclosure is directed to a composition comprising micronized cromolyn sodium, α-lactose, and a salt of fatty acid, wherein the α-lactose has a particle size distribution of D90 of 45-70 μm, D50 of 10-35 μm, and D10 of 2-13 μm.

David R. Elmaleh, Juan B. Gonzalez

Filed: 27 Sep 19

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28 Jan 21

The invention is directed to a composition comprising cromolyn sodium and ibuprofen, wherein the cromolyn sodium is micronized and the cromolyn sodium and ibuprofen are present in a weight ratio of 1:1-2.

David R. Elmaleh, Juan B. Gonzalez

Filed: 13 Feb 20

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17 Feb 20

The invention is directed to a composition comprising cromolyn sodium and ibuprofen, wherein the cromolyn sodium is micronized and the cromolyn sodium and ibuprofen are present in a weight ratio of 1:1-2.

David R. Elmaleh, Juan B. Gonzalez

Filed: 11 Dec 17

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22 Jan 20

The present disclosure is directed to a composition comprising micronized cromolyn sodium, α-lactose, and a salt of fatty acid, wherein the α-lactose has a particle size distribution of D90 of 45-70 μm, D50 of 10-35 μm, and D10 of 2-13 μm.

David R. Elmaleh, Juan B. Gonzalez

Filed: 26 Sep 19