36 patents
Utility
Methods and Systems to Configure and Use Neural Networks In Characterizing Physiological Systems
14 Sep 23
The exemplified methods and systems facilitate the configuration and training of a neural network (e.g., a deep neural network, a convolutional neural network (CNN), etc.), or ensemble(s) thereof, with a biophysical signal data set to ascertain estimate for the presence or non-presence of disease or pathology in a subject as well as to assess and/or classify disease or pathology, including for example in some cases the severity of such disease or pathology, in a subject.
Ali Khosousi, Timothy William Fawcett Burton, Horace R. Gillins, Shyamlal Ramchandani, William Sanders, Ian Shadforth
Filed: 27 Feb 23
Utility
Multi-sensor Mems System and Machine-learned Analysis Method for Hypertrophic Cardiomyopathy Estimation
27 Jul 23
An exemplary method is disclosed that can be used in the diagnosis of hypertrophic cardiomyopathy (HCM) using a biophysical-sensor system configured to non-invasively and concurrently acquire electrocardiographic signals, seismographic signals, photoplethysmographic, and/or phonocardiographic signals, collectively referred to herein as biophysical signals, from at least the thoracic region of a subject.
Charles R. Bridges, Farhad Fathieh, Shyamlal Ramchandani, Jonathan James Woodward
Filed: 23 Jan 23
Utility
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25 May 23
Phase space tomography methods and systems to facilitate the analysis and evaluation of complex, quasi-periodic system by generating computed phase-space tomographic images and mathematical features as a representation of the dynamics of the quasi-periodic cardiac systems.
Paul Grouchy, Meng Lei, Ian Shadforth, Sunny Gupta, Timothy Burton, Shyamlal Ramchandani
Filed: 29 Sep 22
Utility
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27 Apr 23
The exemplified methods and systems (e.g., machine-learned systems) facilitate the use of respiration rate-related features, or parameters, in a model or classifier to estimate metrics associated with the physiological state of a subject, including for the presence or non-presence of a disease, medical condition, or indication of either.
Mehdi Paak, Timothy William Fawcett Burton, Farhad Fathieh
Filed: 19 Aug 22
Utility
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9 Mar 23
A clinical evaluation system and method are disclosed that facilitate the use of one or more visual features or parameters determined from biophysical signals such as cardiac/biopotential signals and/or photoplethysmography signals that are acquired, in preferred embodiments, non-invasively from surface sensors placed on a patient while the patient is at rest.
Abhinav Doomra
Filed: 19 Aug 22
Utility
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9 Mar 23
A clinical evaluation system and method are disclosed that facilitate the use of features or parameters extracted from biophysical signals in a model or classifier (e.g., a machine-learned classifier) to estimate metrics associated with the physiological state of a patient, including for the presence or non-presence of elevated left ventricular end-diastolic pressure (elevated LVEDP), as an example indicator of a disease medical condition that could be assessed by using the system and method described herein.
Timothy William Fawcett Burton, Shyamlal Ramchandani, Ali Khosousi, Farhad Fathieh, Mohammad Firouzi, Emmanuel Lange, Abhinav Doomra
Filed: 19 Aug 22
Utility
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9 Mar 23
The exemplified methods and systems facilitate the use for diagnostics, monitoring, treatment of one or more wavelet-based features or parameters determined from biophysical signals such as cardiac/biopotential signals and/or photoplethysmography signals that are acquired non-invasively.
Farhad Fathieh, Timothy William Fawcett Burton
Filed: 19 Aug 22
Utility
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9 Mar 23
The exemplified methods and systems facilitate the use, for diagnostics, monitoring, treatment, of one or more power spectral-based features or parameters determined from biophysical signals such as cardiac/biopotential signals and/or photoplethysmography signals that are acquired non-invasively from surface sensors placed on a patient while the patient is at rest.
Farhad Fathieh
Filed: 19 Aug 22
Utility
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9 Mar 23
A clinical evaluation system and method are disclosed that facilitate the use of one or more conduction deviation features or parameters determined from biophysical signals such as cardiac or biopotentials signals.
Farhad Fathieh, Timothy William Fawcett Burton
Filed: 19 Aug 22
Utility
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9 Mar 23
A clinical evaluation system and method are disclosed that facilitate the use of one or more morphologic atrial depolarization waveform-based features or parameters determined from biophysical signals such as cardiac or biopotential signals that are acquired, in preferred embodiments, non-invasively from surface sensors placed on a patient while the patient is at rest.
Emmanuel Lange, Farhad Fathieh
Filed: 19 Aug 22
Utility
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23 Feb 23
The exemplified methods and systems facilitate the use, for diagnostics, monitoring, or treatment, of one or more PPG waveform-based features or parameters determined from biophysical signals such as photoplethysmography signals that are acquired non-invasively from surface sensors placed on a patient while the patient is at rest.
Emmanuel Lange, Farhad Fathieh
Filed: 19 Aug 22
Utility
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23 Feb 23
A system is provided that receives a signal file that includes multiple biophysical signals obtained from a patient by a signal capture or recorder device.
Ian Shadforth, Abhinav Doomra, Ali Hussain, Charlie Pham, Murugathas Yuwaraj, Zhan Huan Zhou
Filed: 19 Aug 22
Utility
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29 Sep 22
The exemplified methods and systems facilitate one or more dynamical analyses that can characterize and identify synchronicity between acquired cardiac signals and photoplethysmographic signals to predict/estimate presence, non-presence, localization, and/or severity of abnormal cardiovascular conditions or disease, including, for example, but not limited to, coronary artery disease, heart failure (including but not limited to indicators of disease or conduction such as abnormal left ventricular end-diastolic pressure disease), and pulmonary hypertension, among others.
Mehdi Paak, Timothy William Fawcett Burton, Shyamlal Ramchandani
Filed: 4 Apr 22
Utility
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23 Jun 22
The exemplified methods and systems facilitate the use, for diagnostics, monitoring, or treatment, of one or more cycle variability based features or parameters determined from biophysical signals such as cardiac or photoplethysmography signals that are acquired non-invasively from surface sensors placed on a patient while the patient is at rest.
Farhad Fathieh, Timothy William Fawcett Burton
Filed: 22 Dec 21
Utility
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12 May 22
The exemplified methods and systems described herein facilitate the quantification and/or removal of asynchronous noise, such as muscle artifact noise contamination, to more accurately assess complex nonlinear variabilities in quasi-periodic biophysical-signal systems such as those in acquired cardiac signals, brain signals, etc.
Michael Garrett, Timothy William Fawcett Burton, Shyamlal Ramchandani, Abhinav Doomra
Filed: 18 Oct 21
Utility
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5 May 22
The present disclosure facilitates capture (e.g., bipolar capture) of differentially-acquired wide-band phase gradient signals (e.g., wide-band cardiac phase gradient signals, wide-band cerebral phase gradient signals) that are simultaneously sampled.
Sunny Gupta, Konstantin Papirov, Jason Woo
Filed: 10 Sep 21
Utility
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5 May 22
The exemplified methods and systems provide a phase space volumetric object in which the dynamics of a complex, quasi-periodic system, such as the electrical conduction patterns of the heart, or other biophysical-acquired signals of other organs, are represented as an image of a three dimensional volume having both a volumetric structure (e.g., a three dimensional structure) and a color map to which features can be extracted that are indicative the presence and/or absence of pathologies, e.g., ischemia relating to significant coronary arterial disease (CAD).
Sunny Gupta, Timothy William Fawcett Burton, Shyamlal Ramchandani
Filed: 10 Sep 21
Utility
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31 Mar 22
The exemplified methods and systems (e.g., machine-learned systems) facilitate the acquisition of ballistocardiographic signals and the determination and use of ballistocardiographic signal related features, or parameters, in a model or classifier to estimate metrics associated with the physiological state of a subject, including for the presence or non-presence of a disease, medical condition, or indication of either.
Ian Shadforth, Jonathan James Woodward, Shyamlal Ramchandani
Filed: 27 Sep 21
Utility
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24 Mar 22
A facility for identifying combinations of feature and machine learning algorithm parameters, where each combination can be combined with one or more machine learning algorithms to train a model, is disclosed.
Paul Grouchy, Timothy Burton, Ali Khosousi, Abhinav Doomra, Sunny Gupta, Ian Shadforth
Filed: 4 Jun 21
Utility
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24 Mar 22
A facility providing systems and methods for discovering novel features to use in machine learning techniques.
Paul Grouchy, Timothy Burton, Ali Khosousi, Abhinav Doomra, Sunny Gupta
Filed: 25 Jun 21