42 patents
Utility
Enhanced-flexibility transducer arrays for delivering TTFields (tumor treating fields)
16 Jan 24
A transducer array for use in tumor-treating fields (TTFields) therapy is particularly suited for use in treating abdominal or thoracic cancers.
Eilon Kirson, Yoram Wasserman, Noa Halavee
Filed: 8 Dec 21
Utility
Generating tumor treating fields (TTFields) with high uniformity throughout the brain
9 Jan 24
This application discloses configurations for arranging transducer arrays on a person's head to impose tumor treating fields (TTFields) in the brain at field strengths that are as uniform as possible throughout the entire brain.
Zeev Bomzon, Ariel Naveh, Ofir Yesharim
Filed: 28 Dec 21
Utility
Delivering tumor treating fields (TTFields) using implantable transducer arrays
2 Jan 24
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram Wasserman, Zeev Bomzon, Hadas Sara Hershkovich, Ariel Naveh, Moshe Giladi, Eilon Kirson, Golan Bar-Tal, Tali Voloshin-Sela
Filed: 14 Feb 23
Utility
Implantable arrays for providing tumor treating fields
12 Dec 23
An implantable apparatus for providing tumor treating fields to a target site is disclosed.
Moshe Giladi, Uri Weinberg
Filed: 2 Jun 21
Utility
Compositions and methods of altering the electric impedance to an alternating electric field
5 Dec 23
Disclosed are methods of altering the electric impedance to an alternating electric field in a target site of a subject, comprising introducing a nanoparticle to a target site in the subject; and applying an alternating electric field to the target site of the subject, wherein the electric impedance in the target site of the subject to the alternating current is altered.
Hadas Hershkovich, Tali Voloshin-Sela, Ze'ev Bomzon
Filed: 30 Nov 20
Utility
Fabricating organic light emitting diodes (OLEDs) using tubulin
14 Nov 23
Organic light-emitting diodes are disclosed comprising an electron transport layer and a hole transport layer.
Aarat Pratyaksh Kalra, Jack Adam Tuszynski, Sahil Deepak Patel, Karthik Shankar
Filed: 22 Jun 21
Utility
Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
18 Jul 23
Tumors can be treated with an alternating electric field.
Yoram Palti, Matan Dishon
Filed: 17 Sep 20
Utility
Applying tumor treating fields (TTFields) via electrodes embedded into skull implants
23 May 23
Tumors inside a person's head (e.g., brain tumors) can be treated using tumor treating fields (TTFields) by positioning capacitively coupled electrodes on opposite sides of the tumor, and applying an AC voltage between the electrodes.
Yoram Wasserman, Uri Weinberg, Zeev Bomzon
Filed: 24 Jul 20
Utility
TTField treatment with optimization of electrode positions based on low frequency (<1MHZ) AC conductivity estimates derived from two MRI images having different repetition times
16 May 23
A 3D model of AC electrical conductivity (at a given frequency) of an anatomic volume can be created by obtaining two MRI images of the anatomic volume, where the two images have different repetition times.
Cornelia Wenger, Catherine Tempel-Brami, Hadas Sara Hershkovich, Moshe Giladi, Zeev Bomzon
Filed: 9 Apr 19
Utility
Optimizing positions of electrodes for applying tumor treating fields (TTFields) by adding a dipole to a 3D model
9 May 23
When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by generating a 3D map of electrical conductivity or resistivity of the anatomic volume.
Yoram Wasserman, Cornelia Wenger, Pedro Michael Cavaleiro Miranda, Zeev Bomzon, Noa Urman, Eilon Kirson, Yoram Palti
Filed: 3 Mar 21
Utility
Methods, systems, and apparatuses for managing transducer array placement
4 Apr 23
Methods, systems, and apparatuses are described for managing placement of transducer arrays on a subject/patient.
Hadas Sara Hershkovich, Zeev Bomzon, Gil Zigelman, Shira Luk-Zilberman, Ori Kook, Oren Ben Zion Bakalo
Filed: 4 May 20
Utility
Delivering tumor treating fields (TTFields) using implantable transducer arrays
21 Mar 23
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram Wasserman, Zeev Bomzon, Hadas Sara Hershkovich, Ariel Naveh, Moshe Giladi, Eilon Kirson, Golan Bar-Tal, Tali Voloshin-Sela
Filed: 12 Sep 22
Utility
High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels
7 Mar 23
This application describes a variety of approaches for generating high voltage sinusoidal signals whose output voltage can be adjusted rapidly, without introducing high-frequency artifacts on the output.
Yoram Wasserman
Filed: 17 Dec 20
Utility
Inhibiting viral infection using alternating electric fields
21 Feb 23
Viral infections in a target region can be inhibited by imposing an alternating electric field in the target region for a duration of time.
Noa Kaynan, Tali Voloshin-Sela, Moshe Giladi, Eilon Kirson
Filed: 9 Jul 19
Utility
Uploading data from an isolated system without compromising isolation
14 Feb 23
A data transfer apparatus (“DTA”) connects to the field generator in a TTFields therapy system using the same connector on the field generator that is used to connect a transducer interface to the field generator.
Yoram Wasserman, Golan Bar-Tal, Michael Varshaver, Shimon Elkabetz
Filed: 4 Mar 22
Utility
System for viewing cell cultures under a microscope whilst applying TTFields
7 Feb 23
An apparatus includes a bottom panel with a transparent region and ceramic sidewalls affixed to the bottom panel to form a container.
Moshe Giladi, Yoram Wasserman, Yoram Palti, Michael Krinitsky, Michael Shtotland
Filed: 16 Jan 18
Utility
Determining a frequency for TTFields treatment based on an electrical characteristic of targeted cancer cells
17 Jan 23
Cancer treatment using TTFields (Tumor Treating Fields) can be customized to each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic (e.g., dielectrophoretic forces, cell membrane capacitance, etc.) of the cancer cells, determining a frequency for the TTFields based on the determined electrical characteristic, and treating the cancer by applying TTFields to the subject at the determined frequency.
Moshe Giladi, Einav Zeevi, Cornelia Wenger, Zeev Bomzon
Filed: 25 Feb 20
Utility
Perforated hydrogel configurations and methods of production and use thereof
27 Dec 22
Improved hydrogel configurations for use with a TTField-generating system is disclosed.
Richard Deslauriers
Filed: 6 Nov 20
Utility
Using alternating electric fields to increase cell membrane permeability
20 Dec 22
Certain substances (e.g., large molecules) that ordinarily cannot traverse the cell membrane of cells can be introduced into cells by applying an alternating electric field to the cell for a period of time, wherein the frequency of the alternating electric field is selected so that application of the alternating electric field increases permeability of the cell membrane.
Edwin Chang, Chirag B. Patel, Sanjiv S. Gambhir, Tali Voloshin-Sela, Yaara Porat, Moshe Giladi
Filed: 3 Jul 19
Utility
Delivering tumor treating fields (TTFields) using implantable transducer arrays
18 Oct 22
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram Wasserman, Zeev Bomzon, Hadas Sara Hershkovich, Ariel Naveh, Moshe Giladi, Eilon Kirson, Golan Bar-Tal, Tali Voloshin-Sela
Filed: 26 Feb 20