44 patents
Utility
Valve
16 Nov 23
A valve including a case 3, a tube 1 disposed in the case 3, a hinge fulcrum 4 disposed in the case 3, a contact member 5 connected to the hinge fulcrum 4 and capable of coming into contact with the tube 1, and a driving device 10 configured to apply a non-contact force to the contact member 5 from outside of the case 3 and change a contact force that is applied to the tube 1 by the contact member 5 to change an inner diameter of the tube 1.
Koji TANABE, Ryoji HIRAIDE, Hiroshi NAKAMOTO, Hiroaki INOUE
Filed: 8 Oct 20
Utility
Culturing System and Method for Culturing Cells
5 Oct 23
The present invention provides a culturing system and method for culturing cells that can culture cells in parallel.
Koji TANABE, Kenta SUTO, Ryoji HIRAIDE
Filed: 20 Jan 23
Utility
Method for Producing Nerve Cell, Method for Producing Motor Neuron, and Method for Screening Neurological Disease Therapeutic Drug
29 Jun 23
A method for producing nerve cells includes introducing NGN1 as a differentiation factor into stem cells.
Koji TANABE
Filed: 27 Dec 22
Utility
Pump
23 Mar 23
A pump is provided that includes a tube 1, tube rotors 21A, 21B, and 21C in contact with the tube 1, a case 3 containing the tube 1 and tube rotors 21A, 21B, and 21C, and a drive apparatus 10 that rotates the tube rotors 21A, 21B, and 21C from outside the case 3 without contacting the tube rotors 21A, 21B, and 21C.
Koji TANABE, Ryoji HIRAIDE, Hiroshi NAKAMOTO, Hiroaki INOUE
Filed: 29 Jan 20
Utility
Method for Culturing Factor-introduced Cells
2 Mar 23
According to the present disclosure, there is provided a method for culturing factor-introduced cells, the method including culturing factor-introduced cells and recovering the factor-introduced cells and seeding at least part of the recovered cells in a medium for seeding.
Koji TANABE, Kenta SUTO
Filed: 22 Jan 21
Utility
Solution Transfer Device
2 Mar 23
An solution transfer device comprises a pump 60 and a substrate 70.
Koji TANABE, Ryoji HIRAIDE, Kazunori BAN, Satoshi KINOSHITA
Filed: 21 Feb 20
Utility
Method for Manufacturing Induced Pluripotent Stem Cells
23 Feb 23
According to the present disclosure, provided is a method for manufacturing induced pluripotent stem cells including preparing cells and introducing RNA into the cells, wherein the RNA includes RNA encoding a reprogramming factor and wherein, in the RNA introduced into the cells, double-stranded RNA is substantially removed.
Koji TANABE, Kenta SUTO
Filed: 22 Jan 21
Utility
Method for Manufacturing Induced Pluripotent Stem Cells
16 Feb 23
According to the present disclosure, there is provided a method for manufacturing pluripotent stem cells including introducing a reprogramming factor into cells and seeding the cells, into which the reprogramming factor is introduced, at a low concentration and culturing the cells.
Koji TANABE, Kenta SUTO
Filed: 22 Jan 21
Utility
Cell Production Device and Cell Production Method
9 Feb 23
This cell production device comprises: a cell production plate that includes a fluid circuit in which a plurality of functional sites are integrated; and a closed type connector that connects the fluid circuit to an external space in a closed manner, wherein the fluid circuit comprises, as the plurality of functional sites, an injection and discharge unit that injects or discharges a fluid into or out of the fluid circuit via the closed type connector, a variable volume unit that stores a fluid that is extruded or withdrawn by the injected or discharged fluid, and a cell induction and culture unit that performs at least one of induction and culture of cells based on the injected fluid.
Kazunori BAN, Satoshi KINOSHITA, Koji TANABE, Ryoji HIRAIDE
Filed: 28 May 20
Utility
Cell Treatment Device, Suspension Culture Vessel, and Stem Cell Induction Method
2 Feb 23
This cell treatment device is provided with: a factor introduction device 30 for introducing a pluripotent induction factor into cells so as to prepare induction factor-introduced cells; and a reprogramming suspension culture vessel for culturing the induction factor-introduced cells that have been prepared by the factor introduction device 30.
Koji Tanabe, Kenta Suto, Ryoji Hiraide
Filed: 23 Sep 22
Utility
Cell Production Device and System Therefor
2 Feb 23
This cell production device comprises: a cell production plate that includes a fluid circuit having a plurality of functional parts integrated therein; and a plurality of closed type connectors that connect the fluid circuit to an external space in a closed manner.
Kazunori BAN, Satoshi KINOSHITA, Koji TANABE, Ryoji HIRAIDE
Filed: 28 May 20
Utility
Microscope Observation System
12 Jan 23
A microscope observation system comprises a cell production device provided with a culture vessel in which cells or cell masses are cultured, a microscope device capable of observing an object including cells or cell masses, a conveying apparatus that conveys the microscope device to the cell production device, and an operating control section that sends a command to the conveying apparatus to temporarily move the conveying apparatus from a current position to a relay position and then to move the conveying apparatus to a target position when focusing the microscope device onto the object, wherein a first distance from the current position to the relay position is a distance necessary to drive an actuator by at least a predetermined amount in order to actuate a rotation shaft or a translation shaft of the conveying apparatus, and a second distance from the current position to the target position is a shorter distance than the first distance.
Kazunori BAN, Satoshi KINOSHITA, Koji TANABE, Ryoji HIRAIDE
Filed: 18 Mar 20
Utility
Somatic Cell Production System
5 Jan 23
A somatic cell production system comprising a preintroduction cell solution-feeding channel 20 through which a preintroduction cell-containing solution passes, a factor introducing device 30 that is connected to the preintroduction cell solution-feeding channel 20 and introduces a somatic cell inducing factor into preintroduction cells to prepare inducing factor-introduced cells, and a cell preparation device 40 in which the inducing factor-introduced cells are cultured to prepare somatic cells.
Koji TANABE, Kenta SUTO, Ryoji HIRAIDE
Filed: 9 Sep 22
Utility
Cell Culture Device
22 Dec 22
A cell culture device (200) includes a cell culture vessel (22) for culturing cells, a factor container (81) for storing a factor, a reagent container (82) for storing a reagent for introducing the factor into the cells, and a flow path for transporting the factor and the reagent from the factor container (81) and the reagent container (82) to the cell culture vessel (22).
Koji TANABE, Ryoji HIRAIDE, Kazunori BAN, Satoshi KINOSHITA
Filed: 30 Oct 20
Utility
Pluripotent Stem Cell Production System
8 Dec 22
A stem cell production system provided with a preintroduction cell-feeding solution channel 20 through which a solution containing cells passes, an induction factor-feeding solution mechanism 21 for feeding a pluripotency induction factor to the preintroduction cell-feeding solution channel 20, a factor introduction device 30 connected to the preintroduction cell-feeding solution channel 20 for making cells with induction factor introduced by introducing the pluripotency induction factor into the cells, a cell mass-making device 40 for making multiple cell masses comprising stem cells by culturing the cells with induction factor introduced, and a packaging device 100 for sequentially packaging each of the multiple cell masses.
Koji TANABE, Brendan KELLY, Kenta SUTO, Hidenori SHIMODA, Ryoji HIRAIDE
Filed: 3 Aug 22
Utility
Cell Processing System and Cell Processing Device
10 Nov 22
A cell processing system comprising an enclosure 601, an outer enclosure 701 that envelops the enclosure 601, an intake air purification filter 602 provided in the enclosure 601, that purifies gas that has been drawn in from outside the enclosure 601, a circulating apparatus, inside the outer enclosure 701, that circulates gas inside and outside the enclosure 601 in such a manner that gas in the outer enclosure 701 is drawn into the enclosure 601 through the intake air purification filter 602 and gas inside the enclosure 601 is discharged into the outer enclosure 701, and a cell processing apparatus for processing of cells, disposed inside the enclosure 601.
Koji TANABE, Ryoji HIRAIDE
Filed: 26 Jul 22
Utility
Cell Production Device
10 Nov 22
This cell production device comprises: a cell production plate with a first side and a second side, comprising a cell induction and culture tank configured to perform at least one of induction and culture of cells, and a culture medium reservoir tank configured to store a culture medium to be supplied to the cell induction and culture tank; a warming element that is arranged at or near the first side of the cell production plate and that warms the cell induction and culture tank; and a cooling element that is arranged at or near the second side of the cell production plate and that cools the culture medium reservoir tank.
Kazunori BAN, Satoshi KINOSHITA, Koji TANABE, Ryoji HIRAIDE
Filed: 28 May 20
Utility
Erythrocyte Removal Device, Mononuclear Cell Collector, Cell Culture Device, Cell Culture System, Cell Culture Method, and Method for Collecting Mononuclear Cells
29 Sep 22
Provided is an erythrocyte removal device 100 including a blood container 10 that holds blood and an erythrocyte removal vessel 11 that at least partially removes erythrocytes from blood.
Koji TANABE, Ryoji HIRAIDE, Kiyonori INABA, Kazunori BAN, Satoshi KINOSHITA
Filed: 10 Jun 20
Utility
Erythrocyte Removal Device, Mononuclear Cell Collector, Cell Culture Device, Cell Culture System, Cell Culture Method, and Mononuclear Cell Collection Method
29 Sep 22
Provided is a cell culture method including introducing a factor into cells in a cell culture vessel, and culturing the cells into which the factor has been introduced in the same cell culture vessel.
Koji TANABE, Ryoji HIRAIDE, Kenta SUTO
Filed: 10 Jun 20
Utility
Cell Culture Vessel and Cell Culture Device
11 Aug 22
There is provided a cell culture vessel for culturing a cell in an interior thereof, wherein a width of a bottom surface is equal to or larger than a height of a side surface, the cell culture vessel comprising a flow path configured to supply a fluid into the interior, and wherein the interior is able to be closed.
Koji TANABE, Ryoji HIRAIDE, Kazunori BAN, Satoshi KINOSHITA
Filed: 23 Jun 20