8 patents
Utility
Radiolabeled Ether Dendrimer Conjugates for Pet Imaging and Radiotherapy
14 Dec 23
Compositions and methods for detecting, monitoring and imaging inflammatory sites or tumors in a subject have been developed.
Jeffrey L. Cleland, Rishi Sharma, Minghao Sun, Santiago Appiani La Rosa
Filed: 29 Oct 21
Utility
Dendrimer Compositions and Methods for Drug Delivery
23 Nov 23
Dendrimer compositions and methods for the treatment of cancer or autoimmune diseases are described.
Jeffrey Cleland, Rishi Sharma, Minghao Sun, Santiago Appiani, Barbara Slusher, Rana Rais, Kannan Rangaramanujam
Filed: 7 Oct 22
Utility
Dendrimer Compositions and Methods for Drug Delivery to Injured Kidney
16 Nov 23
In some aspects, the disclosure provides methods of treating or preventing one or more symptoms of a kidney injury, disease or disorder in a subject in need thereof.
Jeffrey L. Cleland, Kannan Rangaramanujam, Sujatha Kannan, Rishi Sharma, Santiago Appiani La Rosa
Filed: 16 Jul 21
Utility
Triantennary N-acetylgalactosamine Modified Hydroxyl Polyamidoamine Dendrimers and Methods of Use Thereof
27 Jul 23
It has been established that dendrimers conjugated or complexed with the carbohydrate triantennary N-Acetylgalactosamine (triantennary-β-GalNAc) selectively accumulate within hepatocyte cells and selectively deliver therapeutic, prophylactic or diagnostic agents to the liver.
Jeffrey Cleland, Rishi Sharma, Minghao Sun
Filed: 4 Dec 20
Utility
Dendrimer Compositions and Methods for Drug Delivery
20 Jul 23
Dendrimer compositions and methods for the treatment of cancer or autoimmune diseases are described.
Jeffrey Cleland, Rishi Sharma, Minghao Sun, Santiago Appiani
Filed: 4 Dec 20
Utility
Dendrimer Compositions and Methods for Treatment of Severe Acute Respiratory Distress Syndrome
18 Nov 21
A method for treating or preventing one or more symptoms of severe inflammation in the lung of a subject in need thereof includes administering to the subject a composition comprising dendrimers complexed, covalently conjugated, or intra-molecularly dispersed or encapsulated with one or more therapeutic or prophylactic agents, in an amount effective to treat, alleviate or prevent one or more symptoms of severe inflammation.
Jeffrey Cleland, Kannan Rangaramanujam, Sujatha Kannan, Jay Zaveri
Filed: 26 Apr 21
Utility
Dendrimer Compositions and Methods for Drug Delivery to the Eye
10 Jun 21
Dendrimer compositions and methods for the treatment of one or more inflammatory and/or angiogenic diseases and/or disorders of the eye include hydroxyl-terminated dendrimers complexed or conjugated with one or more active agents for the treatment or alleviation of one or more symptoms of the diseases of the eye, and/or for diagnosing the diseases and/or disorders of the eye.
Jeffrey Cleland, Rishi Sharma, Santiago Appiani
Filed: 4 Dec 20
Utility
Dendrimer Compositions and Methods for Drug Delivery
10 Jun 21
Dendrimer compositions and methods for the treatment of cancer or autoimmune diseases are described.
Jeffrey Cleland, Rishi Sharma, Minghao Sun, Santiago Appiani, Barbara Slusher, Rana Rais, Kannan Rangaramanujam
Filed: 4 Dec 20
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