3 patents
Utility
5- and 6-azaindole compounds for inhibition of Bcr-Abl tyrosine kinases
7 Nov 23
The present disclosure relates to compounds and compositions for inhibition of Bcr-Abl tyrosine kinases, methods of preparing said compounds and compositions, and their use in the treatment of various cancers, such as chronic myeloid leukemia (CML).
Joseph P. Lyssikatos, Samuel Kintz, Li Ren
Filed: 13 Dec 22
Utility
Fused tetracyclic quinazoline derivatives as inhibitors of ErbB2
7 Nov 23
The present disclosure relates generally to compounds and compositions thereof for inhibition of ErbB2, including mutant forms of ErbB2, particularly those harboring an Exon 20 mutation, methods of preparing said compounds and compositions, and their use in the treatment or prophylaxis of various cancers, such as lung, glioma, skin, head neck, salivary gland, breast, esophageal, liver, stomach (gastric), uterine, cervical, biliary tract, pancreatic, colorectal, renal, bladder or prostate cancer.
Joseph P. Lyssikatos, Samuel Kintz, Li Ren, Qiang Su
Filed: 1 Nov 22
Utility
5- and 6-azaindole compounds for inhibition of BCR-ABL tyrosine kinases
26 Sep 23
The present disclosure relates to compounds and compositions for inhibition of Bcr-Abl tyrosine kinases, methods of preparing said compounds and compositions, and their use in the treatment of various cancers, such as chronic myeloid leukemia (CML).
Joseph P. Lyssikatos, Samuel Kintz, Li Ren
Filed: 4 Oct 21
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