72 patents
Page 4 of 4
Utility
Process for preparing aminopyrimidine derivatives
12 Jan 21
The present invention provides an improved process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors.
Sang-Ho Oh, Ja-Heouk Khoo, Jong-Chul Lim, Seong-Ran Lee, Hyun Ju, Woo-Seob Shin, Dae-Gyu Park, Su-Min Park, Yoon-Ah Hwang
Filed: 25 Jul 18
Utility
Intermediates useful for the synthesis of aminopyrimidine derivatives, process for preparing the same, and process for preparing aminopyrimidine derivatives using the same
7 Dec 20
The present invention provides a novel process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors.
Sang-Ho Oh, Ja-Heouk Khoo, Jong-Chul Lim, Doo-Byung Lee, Jung-Ae Lee, Jun-Sup Lee, Hyun Ju, Woo-Seob Shin, Sang-Seol Jeon
Filed: 24 Jul 18
Utility
Therapies with 3RD Generation Egfr Tyrosine Kinase Inhibitors
18 Nov 20
The present invention relates to therapies with 3rd generation EGFR tyrosine kinase inhibitors.
Seonmi Kang, Sewoong Oh
Filed: 13 May 20
Utility
Quinazoline Derivative or Its Salt and Pharmaceutical Composition Comprising the Same
14 Oct 20
The present invention provides a quinazoline derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof.
Young-Hwan KIM, Tae-Dong HAN, Dong-Hoon KIM, Eun-Hye JUNG, Su-Bin CHOI, Eui-Chul LEE, Won-Ee CHONG, Jin-Hwi PARK, Jun-Chul PARK, Ho-Woong KANG, Ji-Yeong GAL, Chan-Sun PARK, Jong-Gyun KIM, Su-Youn NAM
Filed: 25 Apr 17
Utility
Novel Aryl or Heteroaryl Triazolone Derivatives or Salts Thereof, or Pharmaceutical Compositions Comprising the Same
15 Jul 20
The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof.
Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Su Bin CHOI, Dong Hoon KIM, Sol PARK, Eun Hye JUNG, Hyun Ho CHOI, Tae Wang KIM, Mi Kyeong JU, Na Ry HA
Filed: 18 Dec 19
Utility
3,3-DIFLUOROALLYLAMINES or Salts Thereof and Pharmaceutical Compositions Comprising the Same
15 Jul 20
The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof.
Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Eui Chul LEE, Sol PARK, Hyok Jun CHO, Cheol Hee LIM, So Young KIM, Hyun Ho CHOI, Da Na JEONG, Na Yeon YANG, Na Ry HA
Filed: 11 Dec 19
Utility
TRIAZOLOPYRIDIN-3-ONES or Their Salts and Pharmaceutical Compositions Comprising the Same
15 Jul 20
The present technology provides triazolopyridin-3-ones or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof.
Tae Dong HAN, Hee Jae TAK, Eun Kyung KIM, Dong Hoon KIM, Su Bin CHOI, Sol PARK, Hyun Ho CHOI, Tae Wang KIM, Mi Kyeong JU, Na Ry HA
Filed: 11 Dec 19
Utility
Novel Intermediates Useful for the Synthesis of Aminopyrimidine Derivatives, Process for Preparing the Same, and Process for Preparing Aminopyrimidine Derivatives Using the Same
1 Jul 20
The present invention provides a novel process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors.
Sang-Ho OH, Ja-Heouk KHOO, Jong-Chul LIM, Doo-Byung LEE, Jung-Ae LEE, Jun-Sup LEE, Hyun JU, Woo-Seob SHIN, Sang-Seol JEON
Filed: 24 Jul 18
Utility
Improved Process for Preparing Aminopyrimidine Derivatives
27 May 20
The present invention provides an improved process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors.
Sang-Ho OH, Ja-Heouk KHOO, Jong-Chul LIM, Seong-Ran LEE, Hyun JU, Woo-Seob SHIN, Dae-Gyu PARK, Su-Min PARK, Yoon-Ah HWANG
Filed: 24 Jul 18
Utility
Diaminopyrimidine derivatives and processes for the preparation thereof
4 May 20
The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof.
Hyun-Joo Lee, Dong-Hoon Kim, Tae-Kyun Kim, Young-Ae Yoon, Jae-Young Sim, Myung-Hun Cha, Eun-Jung Jung, Kyoung-Kyu Ahn, Tai-Au Lee
Filed: 14 Nov 17
Utility
Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same
17 Feb 20
The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof.
Tae Dong Han, Hee Jae Tak, Eun Kyung Kim, Su Bin Choi, Dong Hoon Kim, Sol Park, Eun Hye Jung, Hyun Ho Choi, Tae Wang Kim, Mi Kyeong Ju, Na Ry Ha
Filed: 19 Mar 19
Utility
Dual Function Proteins and Pharmaceutical Composition Comprising Same
22 Jan 20
The present invention provides a dual function protein prepared by linking a biologically active protein and an FGF mutant protein to an Fc region of an immunoglobulin, which has improved pharmacological efficacy, in vivo duration and protein stability.
Jun Hwan KIM, Seyoung LIM, Minji SEO, Hyun Ho CHOI, Dohoon KIM, Mi Kyeong JU, Ju-Young PARK, Seul Gi KIM, Sangmyoun LIM, Jong Gyun KIM, Su Youn NAM
Filed: 27 Oct 16