29 patents
Utility
Sustained-release Anesthetic Compositions and Methods of Preparation Thereof
4 Jan 24
Provided is an anesthetic composition for locally administrating an amide-type anesthetic into a subject in need thereof.
Keelung HONG, Hao-Wen KAO, Yi-Yu LIN, Luke S.S. GUO
Filed: 13 Sep 23
Utility
Pharmaceutical composition for intraarticular delivery
24 Oct 23
The present invention provides methods of treating arthritis.
Keelung Hong, Luke S. S. Guo, Yun-Long Tseng, Sheue-Fang Shih, Po-Chun Chang, Chih-Chiang Tsai, Hong-Hui Lin
Filed: 5 Jan 21
Utility
Sustained-release anesthetic compositions and methods of preparation thereof
24 Oct 23
Provided is an anesthetic composition for locally administrating an amide-type anesthetic into a subject in need thereof.
Keelung Hong, Hao-Wen Kao, Yi-Yu Lin, Luke S. S. Guo
Filed: 28 Aug 18
Utility
Drug delivery system containing phospholipid and cholesterol
3 Oct 23
An ophthalmic drug delivery system that contains phospholipid and cholesterol for prolonging drug lifetime in the eyes.
Sheue-Fang Shih, Po-Chun Chang, Yun-Long Tseng, Luke S. S. Guo, Keelung Hong
Filed: 30 Apr 20
Utility
Pharmaceutical Composition of Intra-articular Corticosteroid for Pain Control
14 Sep 23
Provided is a method for treating joint pain in a subject with arthritis.
Sheue-Fang SHIH, Carl Oscar BROWN
Filed: 5 Aug 21
Utility
Inhalable liposomal sustained release composition for use in treating pulmonary diseases
27 Dec 22
Provided is a liposomal sustained-release composition for use in treatment of pulmonary disease.
Keelung Hong, Jonathan Fang, Yu-Cheng Tseng, Ting-Yu Cheng, Wan-Ni Yu, Jo-Hsin Tang
Filed: 23 Apr 19
Utility
Sustained-release triptan compositions and method of use the same through subdermal route or the like
9 Aug 22
Provided is a sustained-release triptan composition as a suitable depot formulation to carry a therapeutically effective amount of triptan for administration via subcutaneous or intramuscular injection.
Keelung Hong, Hao-Wen Kao, Yi-Yu Lin
Filed: 21 Dec 18
Utility
Pharmaceutical Compositions for Use In Treating Pain
10 Mar 22
Provided is a pharmaceutical composition for use in treating postsurgical pain.
TIEN-TZU TAI, YUN-LONG TSENG, SHEUE-FANG SHIH, MIN-WEN KUO, CARL OSCAR BROWN, HUI-TING WANG, WEENEE YEUN NG JAO, PEI-HSIEN HU, WAN-NI YU, KEELUNG HONG, HAO-WEN KAO, YI-YU LIN
Filed: 26 Feb 20
Utility
Sustained-release Pharmaceutical Compositions Comprising of a Sedative Drug and Uses Thereof
24 Feb 22
The present invention relates to a pharmaceutical composition comprising at least one liposome, a trapping agent and a sedative drug with a high drug to lipid ratio and a high encapsulation efficiency.
Keelung HONG, Walter GWATHNEY, Hao-wen KAO, Yi-yu LIN
Filed: 12 Sep 19
Utility
Sustained-release Pharmaceutical Compositions Comprising an Immunomodulating Agent and Uses Thereof
23 Dec 21
The present invention relates to a pharmaceutical composition comprising at least one liposome and a therapeutic agent for treating an auto-immune disease with a high therapeutic agent to lipid ratio and a high encapsulation efficiency.
Keelung HONG, Walter GWATHNEY, Jonathan FANG, Hao-Wen KAO, Yi-Yu LIN
Filed: 15 Oct 19
Utility
Liposomal Composition Containing Mild Acidic Active Agent
23 Dec 21
Provided is a method for preparing a liposomal composition.
Ke-Ming HUANG, He-Ru CHEN, Keelung HONG
Filed: 4 Aug 21
Utility
Sustained-release Pharmaceutical Compositions Comprising a Therapeutic Agent for Treating Dementia and Uses Thereof
9 Dec 21
The present invention relates to pharmaceutical compositions comprising at least one liposome and a therapeutic agent for treating dementia with a high drug to lipid ratio and a high encapsulation efficiency.
Keelung HONG, Hao-wen KAO, Yi-Yu LIN, Walter GWATHNEY
Filed: 23 Jul 19
Utility
Pharmaceutical Compositions Suitable for Articular Delivery and Use Thereof In Treatment of Joint Pain
4 Nov 21
The present disclosure relates to pharmaceutical composition for the treatment of joint pain.
Yun-Long TSENG, Sheue-Fang SHIH, Po-Chun CHANG, Lo CHANG
Filed: 16 Sep 19
Utility
Controlled drug release liposome compositions and methods thereof
19 Oct 21
The present invention relates to pharmaceutical compositions comprising at least one liposome, at least one polyvalent counterion donor or a pharmaceutically acceptable salt thereof, at least one monovalent counterion donor or a pharmaceutically acceptable salt thereof, and an amphipathic therapeutic agent or a derivative or pharmaceutically acceptable salt thereof.
Pei Kan, Yun-Long Tseng, Han-Chun Ou, Chun-yen Lai
Filed: 7 Jan 19
Utility
Sustained-release Pharmaceutical Compositions Comprising an Antipsychotic Drug and Uses Thereof
7 Oct 21
The present invention relates to a pharmaceutical composition comprising at least one liposome and an antipsychotic drug with a high drug to lipid ratio and encapsulation efficiency.
Keelung HONG, Jonathan FANG, Hao-Wen KAO, Yi-Yu LIN, Walter GWATHNEY
Filed: 31 Jul 19
Utility
Sustained-release Compositions Comprising a Therapeutic Agent for Treating Depression or Anxiety and Uses Thereof
7 Oct 21
The present invention relates to a pharmaceutical composition comprising at least one liposome and a therapeutic agent for treating depression or anxiety, with a therapeutic agent to lipid ratio equal to or higher than about 0.15.
Keelung HONG, Yi-Yu LIN, Hao-Wen KAO
Filed: 31 Jul 19
Utility
Sustained-release Ophthalmic Pharmaceutical Compositions and Uses Thereof
9 Sep 21
The present invention relates to an ophthalmic pharmaceutical composition comprising at least one liposome and a therapeutic agent for treating an eye disease with a high drug to lipid ratio and encapsulation efficiency.
Keelung HONG, Hao-Wen KAO, Yi-Yu LIN, Weiwei FANG
Filed: 9 Sep 19
Utility
Methods to Reduce Complications of Intra-articular Steroid
1 Jul 21
Provided are methods of treating joint pain, comprising administering to a subject in need of joint pain treatment an effective amount of a pharmaceutical composition comprising a lipid mixture comprising one or more lipids; and an effective amount of an intra-articular steroid or a pharmaceutically acceptable salt thereof, wherein the therapeutic efficacy of the intra-articular steroid is sustained but the side effects associated with the intra-articular steroid are reduced.
Sheue-Fang SHIH, Po-Chun CHANG, Ming-Ju WU
Filed: 8 Jul 19
Utility
Inhalable Liposomal Sustained Release Composition for Use In Treating Pulmonary Diseases
20 May 21
Provided is a liposomal sustained-release composition for use in treatment of pulmonary disease.
Keelung Hong, Jonathan Fang, Yu-Cheng Tseng, Ting-Yu Cheng, Wan-Ni Yu, Jo-Hsin Tang
Filed: 23 Apr 19
Utility
Pharmaceutical Composition for Intraarticular Delivery
20 May 21
The present invention provides methods of treating arthritis.
KEELUNG HONG, LUKE S. S. GUO, YUN-LONG TSENG, SHEUE-FANG SHIH, PO-CHUN CHANG, CHIH-CHIANG TSAI, HONG-HUI LIN
Filed: 5 Jan 21