8 patents
Utility
Checkpoint Kinase 1 (CHK1) Inhibitors and Uses Thereof
5 Oct 23
Anthony B. PINKERTON, Stephen Todd MEYER, Jacques MAUGER, Yen Pham Hong TRUONG, Rachelle Janette ELSDON
Filed: 1 Jun 23
Utility
Replication Stress Pathway Agent Compositions and Methods for Treating Cancer
31 Aug 23
Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Zachary D. HORNBY, Sudhir CHOWDHRY, Kristen TURNER, Deepti WILKINSON, Shailaja KASIBHATLA
Filed: 15 Feb 23
Utility
Replication Stress Pathway Agent Compositions and Methods for Treating Cancer
10 Aug 23
Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary D. HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
Filed: 24 Mar 23
Utility
Computer-implemented Methods for Quantitation of Features of Interest In Whole-slide Imaging
20 Apr 23
Methods and systems for quantitation of features of interest (e.g., extrachromosomal DNA) in whole slide images are disclosed herein.
Nam-Phuong NGUYEN, Eva Lorena MORA-BLANCO, Kristen TURNER, Julie WIESE, Jason CHRISTIANSEN, Mihir BAFNA
Filed: 15 Mar 21
Utility
Method of Identifying Extrachromosomal Dna Signatures
6 Apr 23
Provided herein are methods and systems for detecting ecDNA positive cancers and methods and systems for developing signatures of ecDNA positive cancers.
Nam-Phuong NGUYEN, Jason CHRISTIANSEN, Laurence JADIN
Filed: 25 Mar 21
Utility
Replication Stress Pathway Agent Compositions and Methods for Treating Cancer
16 Mar 23
Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
Filed: 21 Oct 22
Utility
Checkpoint Kinase 1 (CHK1) Inhibitors and Uses Thereof
26 Jan 23
Provided herein are compounds and methods for the treatment of cancer.
Anthony B. PINKERTON, Stephen Todd MEYER, Jacques MAUGER, Yen Pham Hong TRUONG, Rachelle Janette ELSDON
Filed: 29 Aug 22
Utility
Replication Stress Pathway Agent Compositions and Methods for Treating Cancer
12 May 22
Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
Filed: 4 Jan 22
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