11 patents
Utility
Analyte Sensor Component
11 Jan 24
A sensor component for use in a system for measuring concentration of analytes in fluid in a fluid line comprises one or more sensing elements having an optical property that varies with the concentration of the analytes and engages with the fluid line such that the sensing elements are exposed to the fluid.
Nicholas Paul BARWELL, Barry Colin CRANE, Alasdair Allan MACKENZIE
Filed: 22 Sep 23
Utility
Sterilisation Of An Analyte Sensor Component
28 Sep 23
A sensor component is sterilised for use in a system for measuring the concentration of one or more analytes in fluid in a fluid line.
Barry Colin CRANE, Janet Lesley WALTERS, Nicholas Paul BARWELL, Praveen SAGAR, Alasdair Allan MACKENZIE
Filed: 25 Jan 22
Utility
Optical component
14 Feb 23
The invention is concerned with methods for producing a useful and highly uniform optical component which is useful in the construction of an optical sensor.
Alasdair Allan Mackenzie, Barry Colin Crane, Nicholas Paul Barwell, Robert Perkins, Praveen Sagar
Filed: 22 Apr 20
Utility
Analyte Sensor Component
11 Aug 22
A sensor component for use in a system for measuring concentration of analytes in fluid in a fluid line comprises one or more sensing elements having an optical property that varies with the concentration of the analytes, and engages with the fluid line such that the sensing elements are exposed to the fluid.
Nicholas Paul BARWELL, Barry Colin CRANE, Alasdair Allan MACKENZIE
Filed: 11 Feb 21
Utility
Calibration of a sensor
26 Apr 22
There is provided a method of calibrating a sensor comprising a luminescent compound having a luminescence that depends on the concentration of an analyte, and a detector configured to detect light emitted by the luminescent compound, the method comprising providing a component comprising the luminescent compound in a package that maintains exposure of the luminescent compound to the analyte at a known first concentration, assembling the component into the sensor and measuring a first value of a characteristic of the luminescence of the luminescent compound while exposed to the analyte at the first concentration, measuring a second value of the characteristic of the luminescence of the luminescent compound while exposed to the analyte at a known second concentration different from the first concentration, and determining parameters representing the dependence of the characteristic of the luminescence on concentration of the analyte using the first value and the second value.
Alasdair Allan Mackenzie, Barry Colin Crane, Nicholas Paul Barwell, Praveen Sagar, Robert Perkins
Filed: 17 Feb 20
Utility
Calibration of a gas sensor
7 Dec 21
There is disclosed a method of calibrating a gas sensor comprising a luminescent compound having a luminescence lifetime that is quenched by a gaseous substance which uses a model of the relationship between the luminescence lifetime and the concentration of the gaseous substance that is modified by a calibration factor representing a proportion of the compound not being exposed to the gaseous substance, the method comprising: measuring values of the luminescence lifetime of the luminescent compound while the gas sensor is exposed to at least two known concentrations of the gaseous substance; and deriving the calibration factor from the measured values of the luminescence lifetime using the model.
Alasdair Allan MacKenzie, Barry Colin Crane, Nicholas Paul Barwell, Praveen Sagar
Filed: 2 May 19
Utility
Optical Component
28 Oct 21
The invention is concerned with methods for producing a useful and highly uniform optical component which is useful in the construction of an optical sensor.
Alasdair Allan Mackenzie, Barry Colin Crane, Nicholas Paul Barwell, Robert Perkins, Praveen Sagar
Filed: 22 Apr 20
Utility
Polymer Matrix for Sensing
16 Sep 21
The invention relates to a polymer matrix for optical sensing of pH and/or carbon dioxide, and a process for producing the polymer matrix.
BARRY COLIN CRANE, NICHOLAS PAUL BARWELL
Filed: 10 Mar 20
Utility
Calibration of a Sensor
19 Aug 21
There is provided a method of calibrating a sensor comprising a luminescent compound having a luminescence that depends on the concentration of an analyte, and a detector configured to detect light emitted by the luminescent compound, the method comprising providing a component comprising the luminescent compound in a package that maintains exposure of the luminescent compound to the analyte at a known first concentration, assembling the component into the sensor and measuring a first value of a characteristic of the luminescence of the luminescent compound while exposed to the analyte at the first concentration, measuring a second value of the characteristic of the luminescence of the luminescent compound while exposed to the analyte at a known second concentration different from the first concentration, and determining parameters representing the dependence of the characteristic of the luminescence on concentration of the analyte using the first value and the second value.
ALASDAIR ALLAN MACKENZIE, BARRY COLIN CRANE, NICHOLAS PAUL BARWELL, PRAVEEN SAGAR, ROBERT PERKINS
Filed: 17 Feb 20
Utility
Validation of sensor calibration
26 Jan 21
There is provided a method of validating a calibration of a sensor represented by a calibrated relationship between concentration of an analyte in a sample and measurements from a sensor of an optical property of a sensing substance, wherein the optical property of the sensing substance has a spectrum that varies with the concentration of the analyte in the sample, and the spectrum has an isosbestic wavelength at which the optical property does not vary with concentration of the analyte, the method comprising making measurements of the optical property at three or more wavelengths of light while the sensing substance is exposed to the sample, determining whether the measurements of the optical property are inconsistent with the calibrated relationship, and outputting a warning signal in response to the measurements of the optical property being inconsistent with the calibrated relationship.
Alasdair Allan Mackenzie, Barry Colin Crane, Nicholas Paul Barwell, Praveen Sagar, Robert Perkins
Filed: 17 Feb 20
Utility
Calibration of a Gas Sensor
4 Nov 20
There is disclosed a method of calibrating a gas sensor comprising a luminescent compound having a luminescence lifetime that is quenched by a gaseous substance which uses a model of the relationship between the luminescence lifetime and the concentration of the gaseous substance that is modified by a calibration factor representing a proportion of the compound not being exposed to the gaseous substance, the method comprising: measuring values of the luminescence lifetime of the luminescent compound while the gas sensor is exposed to at least two known concentrations of the gaseous substance; and deriving the calibration factor from the measured values of the luminescence lifetime using the model.
ALASDAIR ALLAN MACKENZIE, BARRY COLIN CRANE, NICHOLAS PAUL BARWELL, PRAVEEN SAGAR
Filed: 1 May 19
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