6 patents
Utility
Production of Glycosylated Cannabinoids
26 Oct 23
The present disclosure provides methods for making glycosylated cannabinoids including methods using recombinant host cells comprising a pathway capable of producing a cannabinoid and a heterologous nucleic acid that encodes a UDP-glycosyl transferase.
Mathias Schuetz, Gisele Passaia Prietsch
Filed: 3 May 23
Utility
Compositions and Methods for Enhancing Recombinant Biosynthesis of Cannabinoids
7 Sep 23
The present disclosure provides recombinant host cells comprising a pathway capable of producing a cannabinoid and a heterologous nucleic acid that encodes a protein not in the pathway that enhances the host cells’ ability to produce the cannabinoid.
Xueyang FENG, Trish CHOUDHARY, Sheela MULEY, Vincent KAM
Filed: 25 Oct 22
Utility
Recombinant Acyl Activating Enzyme (Aae) Genes for Enhanced Biosynthesis of Cannabinoids and Cannabinoid Precursors
16 Jun 22
The present disclosure provides recombinant host cells comprising a pathway capable of producing a cannabinoid and/or cannabinoid precursor, wherein the pathway comprises an enzyme AAE from a source organism other than Cannabis sativa, such as Humulus lupulus.
Mathias SCHUETZ, Michal PYC
Filed: 10 Dec 21
Utility
Compositions and methods for making terpenoid indole alkaloids
27 Jul 21
Methods that may be used for the manufacture of a class of chemical compounds known as terpenoid indole alkaloids, including tabersonine and catharanthine are provided.
Vincenzo De Luca, Yang Qu
Filed: 2 Mar 17
Utility
Compositions and Methods for Making Noscapine and Synthesis Intermediates Thereof
27 May 21
Methods that may be used for the manufacture of the therapeutic chemical compound noscapine and noscapine synthesis intermediates.
Peter James Facchini, Xue Chen, Thi Thu Thuy Dang
Filed: 27 Aug 20
Utility
N-alkylation of Alkaloid Compounds
25 Mar 21
Disclosed are methods for converting an alkaloid substrate compound into a N-alkylated alkaloid product compound in the presence of an alkyl donor compound and catalytic quantities of an N-alkyltransferase enzyme capable of converting the alkaloid substrate into an alkylated product.
Peter J. Facchini, Jillian M. Hagel, Jeremy S. Morris
Filed: 31 Jul 18
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