13 patents
Utility
Method for Treating Sjogren's Syndrome Using Taci-fc Fusion Protein
18 Jan 24
Provided are a drug for treating Sjogren's syndrome using a TACI-Fc fusion protein, and a dosage regimen, a dosing interval and an administration mode thereof.
Jianmin FANG, Wenxiang WANG
Filed: 29 Sep 22
Utility
Method for Treating Iga Nephropathy with Taci-fc Fusion Protein
4 Jan 24
The present invention relates to a drug for treating IgA nephropathy with a TACI-Fc fusion protein, a dose regimen, an administration interval and an application method.
Jianmin FANG, Wenxiang WANG
Filed: 9 Aug 22
Utility
Anti-claudin 18.2 Antibody and Antibody-drug Conjugate Thereof
31 Aug 23
Provided are an antibody targeting Claudin 18.2, an antibody-drug conjugate, and use thereof in treatment of cancer.
Jianmin FANG, Yuanhao LI, Marie M. ZHU, Jing JIANG, Yuelei SHEN, Shenjun LI, Wenting LUO, Xiaoping ZHANG, Lili WANG, Ling WANG, Qinbin ZHANG, Fang YANG
Filed: 7 May 22
Utility
Bispecific Fusion Protein and Application Thereof
30 Jun 22
Provided is a bispecific fusion protein having a novel structure.
Jianmin Fang
Filed: 19 Mar 21
Utility
Anti PD-L1 Antibody and Use Thereof
9 Jun 22
Provided in the present invention is a PD-L1 immunosuppressant, and specifically provided are a monoclonal antibody capable of targeting PD-L1, and nucleotides, combinations of polynucleotides, expression vectors and combinations of expression vectors encoding the antibody.
Jianmin FANG, Jing JIANG, Shenjun LI, Guorui ZHAO
Filed: 25 Aug 20
Utility
Pharmaceutical Taci-fc Fusion Protein Formulation
5 May 22
Disclosed is a pharmaceutical formulation containing a mixture of a non-reducing sugar, a TACI-Fc fusion protein and at least one amino acid.
Qiaoyu Xu, Zhuanglin Li, Xuejing Yao, Jianmin Fang
Filed: 9 Dec 20
Utility
Linker for Antibody-drug Conjugates and Its Use
10 Mar 22
The present invention provides a linker for preparing antibody-drug conjugates and antibody-drug conjugates prepared by the linker, as well as use of the antibody-drug conjugates in a medicament for treating tumor.
Changjiang Huang, Hui Ye, Hu Chen, Xiuzhi Zhan, Nan Shen, Wenting Luo, Qiaohua Hou, Jianmin Fang
Filed: 13 Dec 19
Utility
Anti-mesothelin Antibody and Antibody Drug Conjugate Thereof
24 Feb 22
The present invention discloses an antibody drug conjugate that targets MSLN.
Jianmin Fang, Changjiang Huang, Jing Jiang, Hui Ye, Shenjun Li, Qiaoyu Xu, Wenting Luo, Mingxue Wang
Filed: 15 May 19
Utility
Taci-fc Fusion Proteins and Uses Thereof
6 Jan 22
The present invention relates to an optimized TACI-Fc fusion protein and use of the same in the manufacture of a medicament for treating systemic lupus erythematosus, and a dosage regimen or method for treating systemic lupus erythematosus using the TACI-Fc fusion protein.
Jianmin Fang, Wenxiang Wang, Lin Li
Filed: 24 Dec 19
Utility
Bifunctional Angiogenesis Inhibitor and Use Thereof
21 Oct 21
The present invention relates to a bifunctional angiogenesis inhibitor, which has VEGF inhibitory activity and FGF inhibitory activity, and can inhibit VEGF and FGF dual factors-induced or high glucose-induced cell proliferation, cell migration, and/or lumen formation.
Jing Jiang, Jianmin Fang, Xuejing Luan, Xuejing Yao, Ling Wang
Filed: 4 Dec 19
Utility
Antibody for HER2 Concomitant Diagnosis Immunohistochemical Detection and Application Thereof
5 Aug 21
The invention provides an antibody for human epidermal growth factor receptor 2 (Her2) concomitant diagnostic immunohistochemical detection (IHC).
Zhanjiao YU, Yuanhao LI, Changjiang HUANG, Wang LIANG, Haiyan MAO, Jianmin FANG
Filed: 25 Feb 20
Utility
Pharmaceutical Formulations of HER2 Antibody-drug Conjugate
27 May 21
The invention relates to a pharmaceutical formulation comprising a mixture of a non-reducing sugar, a recombinant humanized anti-Her2 monoclonal antibody-MMAE conjugate, and a surfactant.
Zhuanglin Li, Qiaoyu Xu, Xuejing Yao, Qianjing Bao, Jianmin Fang
Filed: 25 Mar 20
Utility
Application of Taci-fc Fusion Protein In Preparation of Drugs for Treating Neuromyelitis Optica Spectrum Disorders and Multiple Sclerosis
25 Mar 21
The present invention relates to the field of B-lymphocyte stimulator receptor-antibody fusion proteins for treating autoimmune diseases, and in particular to a TACI-Fc fusion protein in preparation of drugs for treating neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS).
Jianmin Fang, Jing Jiang, Shenjun Li, Min Huang
Filed: 15 May 19
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