11 patents
Utility
Inducible Cell Death Systems
21 Dec 23
Provided herein are compositions and methods for inducing cell death in a regulated manner, for example in a safety switch system.
Rocky CHEUNG, Russell Morrison GORDLEY, Timothy Kuan-Ta LU, Michelle Elizabeth HUNG, Rebecca Tayler COTTMAN
Filed: 18 May 23
Utility
Chimeric Receptors and Methods of Use Thereof
23 Nov 23
Provided herein are EMCN-specific antigen-binding domains, and chimeric proteins including the EMCN-specific antigen-binding.
Brian Scott GARRISON, Michelle Elizabeth HUNG, Nicholas FRANKEL
Filed: 14 Apr 23
Utility
Combinatorial Cancer Immunotherapy
31 Aug 23
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer.
Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang
Filed: 25 Jul 22
Utility
Inhibitory Chimeric Receptor Architectures
31 Aug 23
Provided herein are inhibitory chimeric antigen receptor compositions and cells comprising such compositions.
Russell Morrison Gordley, Marcela Guzman Ayala, Gary Lee, Nicholas Frankel
Filed: 18 Aug 22
Utility
Inhibitory Chimeric Receptor Architectures
27 Jul 23
Provided herein are inhibitory chimeric antigen receptor compositions and cells comprising such compositions.
Wilson Wong, Seunghee Lee, Russell Morrison Gordley, Marcela Guzman Ayala, Gary Lee, Nicholas Frankel, Xi Kang
Filed: 17 Aug 22
Utility
Method and Compositions for Regulated Armoring of Cells
12 Jan 23
Provided herein are compositions and methods for regulating expression of effector molecules using regulatable transcription factors and/or activation inducible promoters.
Marcela Guzman Ayala, Russell Morrison Gordley, Michelle Elizabeth Hung, Gary Lee, Jack Tzu-Chiao Lin, Timothy Kuan-Ta Lu, Assen Boyanov Roguev
Filed: 10 Jun 22
Utility
Chimeric Receptor Sensors
15 Dec 22
Provided herein are generalized extracellular molecule sensors (GEMSs) and polynucleotides encoding the GEMSs.
Russell Morrison Gordley, Daniel Frimannsson, Michelle Elizabeth Hung
Filed: 30 Oct 20
Utility
Combinatorial Cancer Immunotherapy
1 Dec 22
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer.
Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
Filed: 23 Jun 22
Utility
Combinatorial cancer immunotherapy
20 Sep 22
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer.
Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang
Filed: 13 Apr 18
Utility
Chimeric Inhibitory Receptor
15 Sep 22
Provided herein are chimeric inhibitory receptor constructs and compositions, and cells comprising the same.
Russell Morrison Gordley, Nicholas Frankel
Filed: 20 Aug 20
Utility
Combinatorial cancer immunotherapy
23 Aug 22
Provided herein are methods and compositions for dynamically controlling and targeting multiple immunosuppressive mechanisms in cancer.
Timothy Kuan-Ta Lu, Russell Morrison Gordley, Jack Tzu-Chiao Lin, Brian Scott Garrison, Philip Janmin Lee, Alba Gonzalez-Junca, Don-Hong Wang, Daniel Frimannsson
Filed: 31 Mar 21
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