5 patents
Utility
Treatment of Autoimmune Diseases with a Dihydroorotate Hehydrogenase (Dhodh) Inhibitor
7 Dec 23
A method of treating an autoimmune disease in a patient comprising administering a therapeutically effective amount of a DHODH inhibitor or a pharmaceutically acceptable salt thereof.
Robert MOORE, Isana ENDO, Carl FIRTH, Stephen DOYLE, Nuria GODESSART MARINA
Filed: 15 Oct 21
Utility
Bispecific Molecules and Methods of Treatment Using the Same
23 Nov 23
The present invention relates to bispecific antigen binding molecules targeting (i) IL-13 or IL-13R and (ii) OX40L or OX40, pharmaceutical compositions comprising the same, and methods of treatment using the same, e.g. in treating a dermatological disease or condition such as atopic dermatitis.
Edward HSIA, Vicente Marco GARCÍA GONZÁLEZ
Filed: 12 Oct 21
Utility
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27 Jul 23
The present invention provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36α, IL-36β, and/or IL-36γ, and block the IL-36 stimulated signaling pathways.
Thomas Huber, Vicente Marco Garcia Gonzalez, Bernat Vidal Juan, Germaine Fuh-Kelly, Yao-ming Huang
Filed: 21 Jun 21
Utility
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14 Mar 23
Pharmaceutical compositions are described comprising (a) dimethyl fumarate, (b) a diluent selected from monosaccharides, disaccharides, starch and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof, (c) microcrystalline cellulose and (d) croscarmellose sodium, wherein the dimethyl fumarate is not covered with a gastroresistant coating.
Jorge Aubets Mir
Filed: 25 Jun 18
Utility
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16 Jun 22
Dapsone and dapsone/adapalene compositions can be useful for treating a variety of dermatological conditions.
Kevin S. WARNER, Ajay P. PARASHAR, Vijaya SWAMINATHAN, Varsha BHATT
Filed: 8 Mar 22
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