11114 patents
Page 7 of 556
Utility
Solid Formulation
4 Jan 24
The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient; and one of or a combination of methacrylic acid copolymer, or a cellulose derivative wherein the active pharmaceutical ingredient is a dengue viral replication inhibitor.
Donghua Zhu, Kristof Leonard Kimpe, Sune Klint Andersen, Matthieu Jean M. Ravelingien, Ivan Henri M. Somers
Filed: 3 Nov 21
Utility
Methods of Treating Prostate Cancer
4 Jan 24
Disclosed are methods of treating prostate cancer by administering niraparib to a human in need thereof.
Marco Gottardis, Rebecca Hawkins, Linda A. Snyder, Douglas H. Yamada
Filed: 13 Sep 23
Utility
Catheter with Improved Loop Contraction and Greater Contraction Displacement
4 Jan 24
A catheter with a variable circular loop is responsive to a contraction wire for increasing the coiling of the circular loop.
Ricardo PADILLA, Homero PADILLA, Julie BUI, Mario SOLIS, Thomas SELKEE, Jose JIMENEZ, Keshava DATTA, Fernando SALAZAR
Filed: 18 Sep 23
Utility
System for Determining Disposal of Surgical Instrument and Related Methods
4 Jan 24
A method of determining a disposal methodology of a surgical kit includes determining a geographical location in which the surgical kit is being used, generating a location data based on the geographical location, and providing the location data set to a resource device.
Frederick E. Shelton, IV, Jacqueline C. Aronhalt, Matthew D. Cowperthwait, Shane R. Adams, Taylor W. Aronhalt, Joseph D. Paulowski, Cesar Perez
Filed: 30 Jun 22
Utility
Safe and Effective Method of Treating Ulcerative Colitis with Anti-IL12/IL23 Antibody
4 Jan 24
Described are methods and compositions for clinical proven safe and effective treatment of ulcerative colitis, particularly moderately to severely active ulcerative colitis in patients who have had an inadequate response to or are intolerant of a conventional or existing therapy by intravenous and/or subcutaneous administration of an anti-IL-12/IL-23p40 antibody.
Jewel Johanns, Katherine Li, Colleen Marano, Richard Strauss, Hongyan Zhang, Christopher O'Brien, Omoniyi Adedokun, Kimberly Shields-Tuttle
Filed: 16 Jun 23
Utility
Surgical System and Methods for Instrument Assessment and Cleaning
4 Jan 24
A method of determining a recovery capacity of at least one feature of a surgical instrument includes establishing communication with the surgical instrument; assisting operation of the surgical instrument during a procedure; obtaining data related to the surgical instrument; evaluating the data obtained related to the surgical instrument to determine a digital assessment of the impact on performance of the at least one features of the surgical instrument; and determining, based on the digital assessment, a capacity of recovery for the at least one feature of the surgical instrument.
Frederick E. Shelton, IV, Jacqueline C. Aronhalt, Matthew E. Derrico, Cameron D. McLain, Bruce Brunson, Gregory A. Trees
Filed: 30 Jun 22
Utility
Ophthalmic Lens with an Optically Non-coaxial Zone for Myopia Control
4 Jan 24
The present disclosure relates to ophthalmic devices such as ophthalmic lenses.
Noel A. Brennan, Xu Cheng, Jaclyn V. Hernandez, Michael J. Collins, Brett A. Davis, Fan Yi, Derek Dean Nankivil
Filed: 15 Sep 23
Utility
Machine Learning to Predict Lung Cancer Involvement of Lymph Nodes
4 Jan 24
Disclosed herein are methods for determining a subject level risk of metastatic cancer involving the training and/or deployment of models to determine 1) a lymph node level risk of individual lymph node involvement and/or 2) a subject level risk of lymph node involvement.
George R. Washko, JR., Raul San Jose Estepar, Charles Matthew Kinsey, Christopher Scott Stevenson
Filed: 30 Nov 21
Utility
Surgical Instrument Recognition from Surgical Videos
4 Jan 24
A machine learning model has two stages.
Bokai ZHANG, Darrick STURGEON, Arjun SHANKAR, Varun GOEL, Jocelyn BARKER
Filed: 30 Jun 23
Utility
Method of Reclaiming Portions of Surgical Instruments for Remanufacturing and Sustainability
4 Jan 24
A method of reclaiming portions of a surgical kit having a surgical instrument includes disassembling the surgical instrument and determining a disposal methodology of the surgical kit.
Frederick E. Shelton, IV, Jacqueline C. Aronhalt, Shane R. Adams, Taylor W. Aronhalt, David A. Bruns, Bruce Brunson, JR., Ellen Burkart, Robert N. Carranza, Matthew D. Cowperthwait, Aaron J. Chow, Matthew E. Derrico, Kevin M. Fiebig, Guion Y. Lucas, Cameron D. McLain, Joseph D. Paulowski, Cesar Perez, Nicholas J. Ross, Patrick J. Scoggins, Rebecca Spatholt, Gregory A. Trees
Filed: 30 Jun 22
Utility
Method and System for Extracting an Actual Surgical Duration from a Total Operating Room (Or) Time of a Surgical Procedure
4 Jan 24
Embodiments described herein provide various examples of a system for extracting an actual procedure duration composed of actual surgical tool-tissue interactions from an overall procedure duration of a surgical procedure on a patient.
Jagadish Venkataraman, Pablo Garcia Kilroy
Filed: 21 Jun 23
Utility
Surgical Instrument with Removable Cable and Associated Couplings
4 Jan 24
A surgical device and method of processing includes a cable and a first adapter.
Robert N. Carranza, Frederick E. Shelton, IV
Filed: 30 Jun 22
Reissue
Bone plate
2 Jan 24
A bone plate includes a first through hole extending through the plate along a first longitudinal axis from a proximal surface of the plate to a bone-facing distal surface thereof which, when the plate is placed on a target portion of bone in a desired orientation, faces the bone.
Beat Roth, Urs Hulliger
Filed: 26 Nov 19
Utility
Surgical hub spatial awareness to determine devices in operating theater
2 Jan 24
A surgical hub is disclosed.
Frederick E. Shelton, IV, David C. Yates, Jason L Harris, Daniel E. Alesi
Filed: 29 Mar 18
Utility
Robotically-controlled shaft based rotary drive systems for surgical instruments
2 Jan 24
A surgical instrument including an end effector that has a selectively reciprocatable implement movably supported therein.
Richard W. Timm, Frederick E. Shelton, IV
Filed: 31 Mar 22
Utility
Surgical instruments with combination function articulation joint arrangements
2 Jan 24
Surgical instruments that have articulation joints that include a distal joint member and a central joint member that is selectively articulatable relative to the central joint member about a distal articulation axis that is transverse to a shaft axis.
Spencer J. Witte
Filed: 28 Jun 21
Utility
Stapling assembly components having metal substrates and plastic bodies
2 Jan 24
A surgical stapling assembly is disclosed.
Frederick E. Shelton, IV
Filed: 24 Mar 21
Utility
Surgical instrument comprising a rotation-driven and translation-driven tissue cutting knife
2 Jan 24
A surgical instrument comprising a rotatable and translatable firing member is disclosed.
Frederick E. Shelton, IV, Chester O. Baxter, III, Taylor W. Aronhalt
Filed: 30 Apr 21
Utility
Tissue thickness compensator comprising controlled release and expansion
2 Jan 24
A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid.
Chester O. Baxter, III, Frederick E. Shelton, IV, Charles J. Scheib, Christopher W. Widenhouse, William B. Weisenburgh, II, Samuel P. Tidwell, Stephanie A. Mutchler, Gary W. Knight
Filed: 10 Mar 21
Utility
Surgical instrument including first and second articulation joints
2 Jan 24
Surgical end effectors and fastener cartridges having firing lockout arrangements for preventing or limit a firing stroke when a cartridge has not been operably installed in the end effector or a spent cartridge has not been replaced.
Frederick E. Shelton, IV, Chester O. Baxter, III, Jeffrey S. Swayze, Jerome R. Morgan
Filed: 31 Mar 22