47 patents
Utility
TRIAZOLO[4,5-D] Pyramidine Derivatives and Their Use As Purine Receptor Antagonists
30 Mar 23
Samantha Jane Bamford, Roger John Gillespie, Richard Simon Todd
Filed: 24 Aug 22
Utility
Methods of detection using X-ray fluorescence
7 Feb 23
The present invention relates, in part, to methods of using X-ray fluorescence (XRF) spectrometry for analyzing (e.g., measuring) the binding of a soluble target to an insoluble material.
Nathan Zahler, Jonathan Theile
Filed: 14 Sep 18
Utility
Nucleotide prodrug compounds
31 Jan 23
Provided herein are nucleotide prodrug compounds, their preparation and their uses, such as treating diseases or conditions of a viral infection.
Lin Zhi
Filed: 8 Jun 22
Utility
Method and apparatus for measuring protein post-translational modification
24 Jan 23
The present invention includes a method for analyzing reactions.
Eva R. Birnbaum, Benjamin P. Warner, Sharon M. Baldwin, Jennifer A. Berger, Lori J. Peterson-Court, Michael N. Harris, Rebecca L. E. Miller
Filed: 23 Jan 20
Utility
Humanized antibodies with ultralong complementary determining regions
20 Dec 22
The present disclosure provides humanized antibodies, including antibodies comprising an ultralong CDR3 and uses thereof.
Omar Bazirgan, Miguel De Los Rios
Filed: 26 Mar 20
Utility
Apparatus and Methods for Laser-based Single Cell Recovery from Microcapillary Arrays
24 Nov 22
Systems and methods for recovering content of a sample from a microcapillary array are provided.
Bob CHEN, Austin BLANCO, Ryan Lewis KELLY, Frances LIU, Derek CROOTE, Samuel Timothy HATCH
Filed: 6 Nov 20
Utility
Methods and systems for screening using microcapillary arrays
18 Oct 22
High-throughput methods for screening large populations of variant proteins are provided.
Jennifer R. Cochran, Bob Chen, Spencer Caleb Alford
Filed: 11 Dec 17
Utility
Nucleotide Prodrug Compounds
22 Sep 22
Provided herein are nucleotide prodrug compounds, their preparation and their uses, such as treating diseases or conditions of a viral infection.
Lin Zhi
Filed: 8 Jun 22
Utility
Bcat Modulation
1 Sep 22
This disclosure relates to, in part, the treatment of an organic acidemia in a subject in need thereof via administration of a therapeutically effective amount of compounds that inhibit BCAT2.
Paul R. August, Margaret Kenney, Jacques Mauger, Mark Drew, Weixi Kong
Filed: 8 Jul 20
Utility
Methods and compositions associated with the granulocyte colony-stimulating factor receptor
16 Aug 22
Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR).
Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelis Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
Filed: 10 Jul 20
Utility
SIRP-gamma polypeptide compositions and treatment of cancer
9 Aug 22
Provided herein are SIRP-gamma, SIRP-beta or SIRP-beta2 decoy polypeptides for immunotherapy and/or treatment of cancer, anemia, transplant, asthma, allergy, auto-immune disease, and viral infection.
Aaron Michael Ring, Roy Louis Maute, Andrew Curtis Kruse, Aashish Manglik, Kenneth S. Lin
Filed: 4 May 20
Utility
Cyclic Phosphate Compounds
14 Jul 22
Provided herein are cyclic phosphate compounds, their preparation and their uses, such as treating liver diseases or conditions or a disease or condition in which the physiological or pathogenic pathways involve the liver.
Lin Zhi
Filed: 21 Apr 20
Utility
Apj Modulators and Uses Thereof
14 Jul 22
Described herein are protein scaffolds comprising an apelin (APJ) receptor binding domain.
Roy Louis MAUTE, John S. BURG
Filed: 18 Jun 20
Utility
Crystalline Forms and Methods of Producing Crystalline Forms of a Compound
30 Jun 22
Disclosed herein are methods of crystallizing the compound of Formula (I), as well as crystalline forms thereof.
Lin Zhi, Henri Sasmor
Filed: 16 Apr 20
Utility
Selective androgen receptor modulators (SARMs) and uses thereof
14 Jun 22
Lin Zhi
Filed: 3 Aug 20
Utility
Methods and Systems for Screening Using Microcapillary Arrays
26 May 22
High-throughput methods for screening large populations of variant proteins are provided.
Vivian Hsieh, Bob Chen, Ryan Lewis Kelly
Filed: 6 Apr 20
Utility
Heterocycle Amines and Uses Thereof
21 Apr 22
Compounds and methods in the fields of chemistry and medicine are disclosed.
Koc-Kan Ho, David Diller, Jeffrey J. Letourneau, Brian F. McGuinness, Andrew G. Cole, David Rosen, Cornelis A. van Oeveren, Jason C. Pickens, Lin Zhi, Yixing Shen, Bijan Pedram
Filed: 28 Oct 21
Utility
Prodrug compounds and their uses
22 Mar 22
Provided herein are prodrug compounds, their preparation and their uses, such as treating liver diseases or nonliver diseases via intervening in molecular pathways in the liver.
Lin Zhi
Filed: 30 Aug 19
Utility
Multi-stage Sample Recovery System
10 Feb 22
Multi-stage sample-recovery systems, including automated 2-stage and 3-stage sample-recovery systems, are provided.
Bob Chen
Filed: 20 Oct 21
Utility
Heterocycle amines and uses thereof
30 Nov 21
Compounds and methods in the fields of chemistry and medicine are disclosed.
Koc-Kan Ho, David Diller, Jeffrey J. Letourneau, Brian F. McGuinness, Andrew G. Cole, David Rosen, Cornelis A. van Oeveren, Jason C. Pickens, Lin Zhi, Yixing Shen, Bijan Pedram
Filed: 7 Jan 20