5 patents
Utility
PEPTIDE IMMUNOGENS AND FORMULATIONS THEREOF TARGETING MEMBRANE-BOUND IgE FOR TREATMENT OF IgE MEDIATED ALLERGIC DISEASES
31 Aug 23
The present disclosure is directed to IgE EMPD peptide immunogen constructs and formulations thereof for the treatment of IgE-mediated allergic diseases.
Chang Yi WANG, Feng LIN, Jiun Bo CHEN
Filed: 31 Dec 17
Utility
Artificial Promiscuous T Helper Cell Epitopes As Immune Stimulators for Synthetic Peptide Immunogens
13 Jul 23
The present invention is directed to novel promiscuous and artificial T helper cell epitopes (Th epitopes) designed to provide optimum immunogenicity of a target antigenic site.
Chang Yi WANG
Filed: 19 Dec 19
Utility
Peptide Immunogens Targeting Pituitary Adenylate Cyclase-activating Peptide (Pacap) and Formulations Thereof for Prevention and Treatment of Migraine
11 May 23
The present disclosure is directed to peptide immunogen constructs targeting portions of Pituitary adenylate cyclase-activating polypeptide (PACAP), compositions containing the constructs, antibodies elicited by the constructs, and methods for making and using the constructs and compositions thereof.
Chang Yi Wang, Feng Lin, Shuang Ding
Filed: 22 Jan 21
Utility
Designer Peptides and Proteins for the Detection, Prevention and Treatment of Coronavirus Disease, 2019 (COVID-19)
6 Apr 23
The present disclosure is directed to a relief system for the effective detection, prevention, and treatment of COVID-19, including (1) serological diagnostic assays for the detection of viral infection and epidemiological surveillance, (2) high-precision, site-directed peptide immunogen constructs for the prevention of infection by SARS-CoV-2, (3) receptor-based antiviral therapies for the treatment of the disease in infected patients, and (4) designer protein vaccine containing S1-RBD-sFc.
Chang Yi Wang, Feng Lin, Shuang Ding, Wen-Jiun Peng
Filed: 19 Feb 21
Utility
Peptide Vaccine for Prevention and Immunotherapy of Dementia of the Alzheimer's Type
27 Jan 22
The present disclosure is directed to individual Aβ peptide immunogen constructs, peptide compositions comprising these Aβ peptide immunogen constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these Aβ peptide immunogen constructs, with the individual Aβ peptide immunogen constructs having the N-terminus of the Aβ peptide as the B cell (B) epitopes linked through spacer residue(s) to heterologous T helper cell (Th) epitopes derived from pathogen proteins that act together to stimulate the generation of highly specific antibodies directed against the N-terminus of the Aβ peptide offering protective immune responses to patients at risk for, or with, Alzheimer's Disease.
Chang Yi Wang
Filed: 27 Jul 20
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