3 patents
Utility
Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof
21 Sep 20
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions.
Elena Feinstein, Sharon Avkin-Nachum, Hagar Kalinski, Igor Mett
Filed: 1 Apr 18
Utility
Double-stranded RNA compounds to CASP2 and uses thereof
24 Feb 20
The present disclosure relates to methods of treating a patient suffering from or at risk of developing an ocular disease, disorder or injury, and includes treatment regimens using a double-stranded RNA compound that down-regulates CASP2 expression, or a pharmaceutically acceptable salt thereof.
Shai Erlich, James D. Thompson, Rabia Ozden, Elena Feinstein
Filed: 30 Jun 16
Utility
siRNA compounds comprising terminal substitutions
2 Dec 19
The invention relates to modified siRNA compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to methods of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions.
Sharon Avkin-Nachum
Filed: 5 Jul 17
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