302 patents
Page 14 of 16
Utility
Protein Kinase B Inhibitors
29 Jul 20
Paul David Johnson, Andrew Leach, Richard William Arthur Luke, Zbigniew Stanley Matusiak, Jeffrey James Morris
Filed: 6 Apr 20
Utility
Chemical compounds
20 Jul 20
Provided are a series of novel pyridine or pyrimidine derivatives which inhibit CDK9 and may be useful for the treatment of hyperproliferative diseases.
Bernard Barlaam, Christopher De Savi, Janet Hawkins, Alexander Hird, Michelle Lamb, Kurt Pike, Melissa Vasbinder
Filed: 5 Dec 17
Utility
Arginase Inhibitors and Methods of Use
15 Jul 20
David W. Christianson, Bruce Edward Tomczuk, Richard Scott Pottorf, Andrew Vargha Colasanti, Gary Lee Olson
Filed: 21 Aug 19
Utility
Phenoxyquinazoline Compounds and Their Use In Treating Cancer
15 Jul 20
Tudor GRECU, Jason Grant KETTLE, Martin John PACKER, Stuart Eric PEARSON, James Michael SMITH
Filed: 25 Apr 18
Utility
Mpo Inhibitors for Use In Medicine
1 Jul 20
The present disclosure relates to new therapeutic uses of MPO inhibitors and methods of treatment involving the same.
Andrew WHITTAKER, Hitesh Jayantilal SANGANEE
Filed: 11 Jul 18
Utility
Crystalline form of (1R,2R)-2-[4-(3-methyl-1H-pyrazol-5-yl)benzoyl]-N-(4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazin-3-yl)cyclohexanecarboxamide
22 Jun 20
A crystalline form of (1R,2R)-2-[4-(3-Methyl-1H-pyrazol-5-yl)benzoyl]-N-(4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl)cyclohexanecarboxamide, pharmaceutical compositions containing it and its use in the prevention or treatment of cardiovascular diseases.
Anna Matilda Angelica Pettersen
Filed: 26 Oct 17
Utility
Novel Compounds
10 Jun 20
Frank NARJES, Roine Ingemar OLSSON, Stefan VON BERG, Sarah LEVER
Filed: 24 Nov 19
Utility
Pharmaceutical Composition
10 Jun 20
The invention concerns pharmaceutical compositions containing a hydrogen sulphate salt of 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and solvates, crystalline forms and amorphous forms thereof, to the use of said compositions as a medicament; and to processes for the preparation of said compositions.
Nicola Frances BATEMAN, Paul Richard GELLERT, Kathryn Jane HILL
Filed: 8 Oct 19
Utility
Certain (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES for Treating Bronchiectasis
10 Jun 20
Hans Roland LONN, Stephen CONNOLLY, Steven SWALLOW, Reinilde HEYRMAN, Eugene SULLIVAN, Carlos FERNANDEZ
Filed: 14 Jul 19
Utility
ANTI-IFNAR1 Antibodies with Reduced FC Ligand Affinity
3 Jun 20
The invention provides anti-IFNAR1 antibodies with reduced affinity for Fc receptors and/or ligands and methods of making and using such antibodies.
ANTHONY COYLE, PETER KIENER, HERREN WU, RICARDO CIBOTTI
Filed: 7 Apr 19
Utility
Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides dipeptidyl peptidase 1 inhibitors
1 Jun 20
Hans Roland Lonn, Stephen Connolly, Steven Swallow, Staffan Po Karlsson, Carl-Johan Aurell, John Fritiof Pontén, Kevin James Doyle, Amanda Jane Van De Poël, Graham Peter Jones, David Wyn Watson, Jaqueline Anne Macritchie, Nicholas John Palmer
Filed: 18 Mar 19
Utility
Pyrazole Derivatives Useful As 5-LIPOXYGENASE Activating Protein (Flap) Inhibitors
20 May 20
Johan Olof BRODDEFALK, Hans Fredrik EMTENÂS, Kenneth Lars GRANBERG, Malin Anita LEMURELL, Daniel Tor PETTERSEN, Alleyn Thomas PLOWRIGHT, Lars Johan Andreas ULANDER
Filed: 29 Oct 19
Utility
Protein kinase B inhibitors
18 May 20
Paul David Johnson, Andrew Leach, Richard William Arthur Luke, Zbigniew Stanley Matusiak, Jeffrey James Morris
Filed: 5 Jul 18
Utility
Methods For Treating Chronic Obstructive Pulmonary Disease Using Benralizumab
22 Apr 20
Provided herein is are methods of treating Chronic Obstructive Pulmonary Disease (COPD) in a patient, comprising administering to the patient an effective amount of benralizumab or an antigen-binding fragment thereof.
Rene van der Merwe, Christine Ward, Ubaldo Martin, Lorin Roskos, Bing Wang
Filed: 23 May 19
Utility
Novel Compounds
15 Apr 20
Sarah LEVER, Frank NARJES, Roine Ingemar OLSSON, Stefan VON BERG
Filed: 12 Jun 18
Utility
Heteroaryl Compounds That Inhibit G12C Mutant Ras Proteins
8 Apr 20
Jason Grant KETTLE, Sharanjeet Kaur BAGAL, Scott BOYD, Andrew John EATHERTON, Shaun Michael FILLERY, Graeme Richard ROBB, Piotr Antoni RAUBO
Filed: 7 May 18
Utility
Imidazo[4,5-c]quinolin-2-one Compounds and Their Use in Treating Cancer
1 Apr 20
Bernard Christophe Barlaam, Kurt Gordon Pike, Andrew John Eatherton, Thomas Anthony Hunt
Filed: 26 Sep 19
Utility
Chemical compounds
23 Mar 20
Jason Grant Kettle, Sharanjeet Bagal, Graeme Richard Robb, James Michael Smith, Frederick Woolf Goldberg, Doyle Joseph Cassar, James Lyman Feron
Filed: 5 Dec 18
Utility
Deuterated Imidazo[4,5-c]quinolin-2-one Compounds and Their Use in Treating Cancer
18 Mar 20
Kurt Gordon PIKE, Bernard Christophe BARLAAM
Filed: 14 Mar 18
Utility
Selective estrogen receptor down-regulators
16 Mar 20
Johannes Wilhelmus Maria Nissink, James Stewart Scott, Thomas Andrew Moss, Samantha Jayne Hughes, Bernard Christophe Barlaam, Bin Yang
Filed: 30 Jan 19