14 patents
Utility
Simian (gorilla) adenovirus or adenoviral vectors and methods of use
14 Jun 22
The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
Douglas E. Brough, Jason G. D. Gall, Duncan McVey
Filed: 25 Aug 20
Utility
Adenoviral vector encoding human atonal homolog-1 (HATH1)
22 Mar 22
The invention is directed to a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding a human atonal homolog-1 (Hath1) protein operably linked to a human glial fibrillary acidic protein (GFAP) promoter.
Douglas E. Brough, Damodar R. Ettyreddy
Filed: 23 Mar 18
Utility
Adenovectors for delivery of therapeutic genetic material into T cells
26 Oct 21
The invention provides adenoviral vectors and compositions for the highly efficient transduction of T cells.
Sebastien M. Maloveste, Damodar Ettyreddy, Douglas E. Brough
Filed: 29 Sep 17
Utility
Adenovectors for Delivery of Therapeutic Genetic Material into T Cells
30 Sep 21
The invention provides adenoviral vectors and compositions for the highly efficient transduction of T cells.
Sebastien M. Maloveste, Damodar Ettyreddy, Douglas E. Brough
Filed: 13 Apr 21
Utility
Modified Serotype 28 Adenoviral Vectors
2 Sep 21
The invention provides a replication-deficient serotype 28 adenoviral vector characterized by comprising a portion of a serotype 45 adenoviral hexon protein and/or a portion of a serotype 45 fiber protein in place of the endogenous serotype 28 hexon and/or fiber protein.
Lisa Wei, Douglas E. Brough, C. Richter King
Filed: 12 Mar 21
Utility
Affenadenovirus (gorilla) or adenoviral vectors and methods of use
15 Jun 21
The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexone protein, and/or fiber protein.
Jason G. D. Gall, Duncan McVey, Douglas E. Brough
Filed: 22 Feb 19
Utility
Modified serotype 28 adenoviral vectors
16 Mar 21
The invention provides a replication-deficient serotype 28 adenoviral vector characterized by comprising a portion of a serotype 45 adenoviral hexon protein and/or a portion of a serotype 45 fiber protein in place of the endogenous serotype 28 hexon and/or fiber protein.
Lisa Wei, Douglas E. Brough, C. Richter King
Filed: 11 Sep 17
Utility
Simian (Gorilla) Adenovirus or Adenoviral Vectors and Methods of Use
11 Feb 21
The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
Douglas E. Brough, Jason G.D. Gall, Duncan McVey
Filed: 25 Aug 20
Utility
Affenadenovirus (gorilla) or adenoviral vectors and methods of use
5 Oct 20
The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
Duncan McVey, Douglas E. Brough, Jason G. D. Gall
Filed: 12 Mar 19
Utility
Simian (gorilla) adenovirus or adenoviral vectors and methods of use
28 Sep 20
The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
Douglas E. Brough, Jason G. D. Gall, Duncan McVey
Filed: 23 Jul 18
Utility
Malaria antigens and methods of use
21 Sep 20
The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans.
Ping Chen, Duncan McVey, Douglas E. Brough, Joseph Bruder
Filed: 23 Apr 19
Utility
Method for propagating adenoviral vectors encoding inhibitory gene products
4 May 20
The invention provides a method of propagating an adenoviral vector.
Jason G. D. Gall, Douglas E. Brough, C. Richter King
Filed: 6 Sep 17
Utility
Recombinant adenovirus vectored FMDV vaccines and uses thereof
2 Dec 19
The present invention encompasses FMDV vaccines or compositions.
Justin Widener, Leszlie Woodyard, Leonardo Siger, Douglas Brough, Damodar Ettyreddy, Jason Gall, Duncan McVey, Tom Burrage, Lauri Motes-Kreimeyer, Marc Fiorucci
Filed: 16 Jan 19
Utility
Affenadenovirus (Gorilla) or Adenoviral Vectors and Methods of Use
16 Oct 19
The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
Jason G.D. Gall, Duncan McVey, Douglas E. Brough
Filed: 21 Feb 19
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