Arroyo Santiago

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
2 Jan 25	BCYC Bicycle Therapeutics	Ordinary Shares	Sell	Dispose S	No	No	14.09	4,943	69.65 k	69,057
2 Jan 25	BCYC Bicycle Therapeutics	Ordinary Shares	Grant	Acquire A	No	No	0	35,000	0.00	74,000
2 Jan 25	BCYC Bicycle Therapeutics	Employee Stock Option Ordinary Shares	Grant	Acquire A	No	No	14	87,000	1.22 mm	87,000
6 Feb 24	BCYC Bicycle Therapeutics	Ordinary Shares	Grant	Acquire A	No	No	0	21,660	0.00	39,000
6 Feb 24	BCYC Bicycle Therapeutics	Employee Stock Option Ordinary Shares	Grant	Acquire A	No	No	17	41,570	706.69 k	41,570
2 Jan 24	BCYC Bicycle Therapeutics	Ordinary Shares	Grant	Acquire A	No	No	0	17,340	0.00	17,340
2 Jan 24	BCYC Bicycle Therapeutics	Employee Stock Option Ordinary Shares	Grant	Acquire A	No	No	18.08	35,430	640.57 k	35,430

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.