Well, thank you, call good the and joining today. on everyone John, and appreciate we morning, us you
So performance Sciences in positive encouraged core finished particularly of revenue of instruments all Life segments. quarter by business better-than-anticipated strong with in in our our X businesses. momentum our we And another improving the bioprocessing we and were
disciplined flow margin Our drove also cash team's execution solid and profit expansion. operating
with demonstrated which Now navigate a throughout commitment Danaher leading enabled XXXX, dynamic our System, XX,XXX and to us executing to the unwavering environment. associates successfully an operating Business
also our it delivered success. their improvements Now innovations drove which both process Danaher our meaningful not across businesses, customers, only impactful sustainable of long-term positioning for are dedication for
focused long-term Now XXXX beginning and has a life portfolio than diagnostics and Danaher a at sciences beyond, point is better our cash our to growth, of looking in in since history. shaped us XX-year with any believe The the pandemic margin innovator flow transformation the and profile. we re-rated into positioned
create on human DBS technology well impact of positive value with us Our power meaningful paired long-term talented a team, science and our making positions portfolio, differentiated the while to health. and shareholder
look closer our at financial year that, with So let's results. full XXXX take a
core X.X%. revenue and declined billion, $XX.X were Sales
of profit were flat $X.XX. adjusted XX.X% margin common adjusted year-over-year net Our operating and per earnings essentially diluted share was
earnings important flow of flow of approximately resulting billion and free to the the generation XXrd one Strong free which flow net cash speaks exceeded $X.X the also in to of to flow most net models. XXX% income a cash cash year Danaher XXX%. at business of income consecutive cash XXXX our free conversion We and metrics generated and conversion, marks ratio differentiated free of is quality
$X deployed includes capital through X approximately towards quarters second shares of purchased third we XX start and shares million million the fourth million billion This XXXX. of XXXX, repurchase Danaher the in in and XXXX shares into of the stock. the quarter Now and common into and January approximately of approximately purchased XX
We remained the acquisitions front, active also the M&A strategic on completing year. during several
technologies long-term competitive our further these us success. Now sustained and strengthen acquisitions innovative for and position bring that advantages solutions
year, associated critical of therapy our address helping work. access the Cephea is customers we critical efficiencies that make [ several Cephea investments patient technologies potential constraints Now increase introduced cell the innovation to also to these launch to customers' groundbreaking in are through cell which the ] therapy continue substantial therapies. cost In enabling advancing throughout the capacity Cytiva the CAR-T platform and platform, with life-saving manufacturing gained manufacturing. The have biotechnology,
pharmaceutical Coulter introduced culture development In cell And immunoassay the next-generation researchers therapies [ faster. the is XXXx market the in glad bring ] simplifies automated Beckman for XXXX, Diagnostics and more faster ultimately system, enabling strides accelerates Life analyzer. DxI the menus [ patient on XXXX expanding the Coulter Sciences, way greater in traditional SitmVT diagnosis Beckman enabling made ] cell line than accurate sensitivity high-resolution With diagnostics. Life DxI Sciences paving virus to precision Diagnostics, the to significant our immunoassay and process systems, which
growth of the the around examples innovation is how world. helping and health just impacting some important engine few most long-term patients driving a solve are customers challenges These of our
our let's detail. fourth now XXXX more quarter So results in to turn
single-digit up China. with a than America low and in High-growth digits single Western essentially billion X% were market performance core a in delivered single-digit markets of Europe. $X.X fourth outside ] solid low mid-single-digit [ revenue with quarter, revenues low -- core in more North decline a were Sales in Geographically, were growth. developed decline China, the flat in offsetting
profit XX gross XX.X%. for year-over-year increased the Our margin points quarter to basis fourth
year-over-year, of Adjusted we cost generated net margin Our ] of points profit [ the billion driven diluted initiatives. up cash free impact quarter. $X.X per the X.X% primarily of savings share XX.X% adjusted positive operating was up flow in basis were XX and earnings by of $X.XX
and now what at closer end you So the color a we're across give our some portfolio seeing results segments. market in take on let's look our
Biotechnology commercialized revenue low with single digits. high the into business momentum quarter. in were sequentially. high remained by our growth. consecutive Revenue single consumables, as digits and improved, up primarily [indiscernible] recovery subdued while increased discovery demand, by our capital book, was We order driven this Core which encouraged medical represents bioprocessing the digits with sequential continue sustained for by businesses year robust and high bioprocessing, be in customers the our the digits up continued in In cautious single grew quarter segment order single-digit double quarter supported the high year-over-year, positive the And our sixth of through to spending. growth their therapies. gradual fourth particularly demand
as challenges Now in in environment. funding a faced weak China, ongoing underlying but difficult levels stable customers were relatively activity
antibodies. yields The ] was with largest long-term our and same therapies on support and very business, approvals efficiency, and which making time, patents monoclonal today customers long Cytiva's adoption. outlook innovation and the we're on more increasing expire, enhancing accessible XX% continued we're treatments confidence for customers, our trends, [ comprised we in EA investment Monoclonal progress more near production making life-saving comprehensive revenues an bioprocessing and market increasing for XXXX healthy high-volume than broader antibodies, the a area engine biosimilar record our in underlying franchise. for of new coupled With At believe are focused positioned well development remain manufacturing the portfolio for bioprocessing driving as and reinforces our our the to our term.
customers revenue Europe, Core Sciences [ Life Now XX% Instrument was and our modest saw segment. challenging modest exceeding see market our the investments. to turning did expectations. pharma at be to and applied continue U.S. ongoing a revenue our while stimulus our In improvements the China, cautious remain in conditions ]. In customers. their benefit we with from up program, Core increased as Sciences demand slightly business Life we
Stellaris Spectraplex potential of cutting-edge researchers of of ] deeper ], Microsystems platform imaging and introduction -- the microscopy therapeutic [ in advancing identification spatial aiding gain enables XD and in the in disease for the targets. October, progression to spatial organization, ] with In its Leica interactions [ [ biology. cellular Spectraplex the confocal a solution insights expanded understanding
next-generation proteins, plasmas in Now core business in quarter. across writing declined Growth declines basic the gene consumables and products research by editing our sequencing genomics revenue and solutions. in offset than and more was
Moving to our Diagnostics segment. Core revenue decreased X%.
collectively leverage across core accurate gains patient low clinical GT way driven scanners looking a pathology digital to timely record predictive increasingly clinicians number XXX more as its single-digit diagnostics this are diagnosis. advanced delivered quarter, led its core placed and Notably, to and Our digital staining with productivity strength algorithms of deliver Leica has by businesses pathology. XX% and growth. nearly the histology, [indiscernible] growth, revenue slide
partnership artificial recently ], aims expertise software. global in with with diagnostics established leadership To Indica Indica This [ software pathology development capabilities, Biosystems' in pathology digital further strategic the intelligence. Labs' Leica global enhance in by to and Leica Labs instrumentation cancer of accelerate footprint next-generation a extensive combining AI-powered a partnership leader enterprise and
essentially mid-single-digit this volume-based the [indiscernible]. of impact China, the by at procurement assays revenue Core revenue of for in research disease offset XXXX. use-only flat, Beckman neurodegenerative month, Diagnostics on cutting-edge introduced Earlier with several DxI Beckman was research core outside growth
insights with exceptional such into and neurodegenerative providing assays to disease. biomarkers researchers these specificity, Now detect allow quantify Alzheimer's emerging valuable and conditions as sensitivity
transform -- Drug and breakthrough disease. families Alzheimer's. this outcomes ultimately designation ] of [ identifying beta leading granted by clinicians assay with the reflects patients affected to Food PTAOXXX test manage in potential to designed U.S. device the diagnose addition, devastating designation patients to Alzheimer's, aid amyloid improved to and In Beckman's for XXX Beckman's and patients how This
In revenue quarter adoption mid-teens utilization increasing reagent portfolio. system of core contributed Cepheid's Molecular in to menu another and growth core nonrespiratory Diagnostics,
products by enables customers value the growth increasingly prescribe growth or at office quickly the as multiplex need adopting the turnaround diagnose health -- multiple delivered accurately growth MVP. rapid reducing point double-digit multiplex The are visits. quarter VP to to these and panel women's of its highlights Cepheid's care. [ rapid in infections since introduction led physicians and the ] for over vaginitis of in sexual our treatments, All panel health diagnostics of targeted XX% clinicians
volumes a favorable now opportunities ahead our enabling in of and grew high digits XXXX, women's test Flu X-in-X Now is than COVID-XX, respiratory is unlocking beyond significant expand single business as we Cepheid's $XXX both as Cepheid million approximately is growth and RSV. XX,XXX continue of saw our globally. clinical instruments of base B how for A, Flu long-term of exceeded revenue by and our MVP quarter expectation more installed we in the opportunities $XXX a setting.
Cepheid's mix example the higher In outpatient great to improved health outcomes, and million underscores
new of sites, placement by health In recent seen clinical hospital care delivery and This clinics beyond cares. outcomes network care and as customers the at urgent their we've reduce alternate expansion networks. improve integrated instruments care quarters, across costs customers and accelerating the standardizing helps such
of our and With growth. long-term the well menu leading global positioned continued a Cepheid the installed market sustained expansion pipeline, robust innovation the largest base, for is on test
at let's briefly and Now XXXX. ahead year full the the look first expectations for quarter
year anticipate For XXXX, growth the X%. we approximately revenue of full core
approximately revenue expect we dollar. U.S. the an addition, In of due headwind strengthening X% to recent
adjusted range. We expect single-digit year the full In revenue percentage to approximately expect operating profit XX.X%. also we quarter, margin decline the of in core first the low
expect approximately the margin of operating profit we quarter Additionally, adjusted first XX.X%.
into we XXXX. to on with pleased and up, building our -- fourth this move to So quarter performance as momentum wrap we are
to to team executed the a strong continuing future. financial Our environment dynamic for successfully results through invest deliver while
our ahead, today, a positioned growth opportunities with we're in and highly lineup this better that organic to building foundation. transformation the upon growth, paired franchises portfolio, stronger markets. with flow attractive company cash expanded a positioned tremendous very are has -- end And in continue outstanding for long higher created well -- our Looking of margins
team of sheet, combination powerful strong to by talented System, balance to the portfolio, come. value shareholder deliver long-term powered Business all With the and well our Danaher positioned we feel years leading for
back turn So call the with to over John. I'll that,