overview Thanks Marc begin Marc. first total for finish segments company, as with four just I'll around on then comments results the some color our and guidance with of quarter outlined. provide I'll the some an
organic approximately foreign components acquisitions day just and X% the earnings adjusted the And QX one saw growth, top X% our from GAAP of reported year-over-year. with we year-over-year. impact approximately had X% EPS quarter an X% reminder a The revenue QX QX down revenue increase divestitures to year. year line of The and QX headwind this selling reported in starting results, the our $X.XX. from last of included of on our by a release EPS press to X% $X.XX we growth On exchange performance, was components net in of grew under QX So in X% as our about as less QX X%. you in X%. grew
in decline low driven the rest mid-teens Turning quarter, the mentioned, North the growth Europe in XX% to approximately grew the China previously America a during geography the as single digits. of by and Asia-Pacific grew in XX%, mid-single declined by Marc grew our approximately of digit, in world
Looking last operating and our XX X% at performance, QX increased was operating lower year. income basis adjusted adjusted XX.X%, QX operational than margin points
As XX QX. in the basis expected, reinvestment phasing the of year's of last and about in negative benefits acquisitions margins of debt our investment recent refinancing on a impact points had
strong drove PPI our on the impact impact more In from from Business System margins offset addition, team than the COVID-XX. to
QX dilutive divestiture the on of margin. revenue, operating of at $X.XX XX As $XX million was million end year-over-year a on about of $XX and operating and Anatomical approximately in XXXX Pathology basis adjusted XXXX headwind adjusted income our business points the reminder, QX the on
on the quarter our was XXXX. year margin QX Moving than in XX%, X.X%. came total XX year of in of QX R&D of down margin. versus was quarter those in company an in basis similar XX% gross adjusted our of I operating details for manufacturing mentioned the XX P&L, of as R&D QX increase expense basis revenue drivers and to came prior just the a of adjusted in QX SG&A lower Adjusted points the percent to basis Total the with in at last points revenue, revenue points XX X.X% at
interest of line refinancing was reduction Looking year. by expense at the issued our net the we of down expense for $XX before a $XX was million net results to just QX was foreign income interest end last million had cash quarter QX debt million, quarter related $XX income XXXX on to our due impact The our in the driven expense pooling non-operating actions. immaterial in The million primarily Adjusted largely below arrangements. exchange net the an this by from in than changes our quarter the higher results. $XX QX other XXXX and
the adjusted versus XXX lower the points basis X million repurchases QX, in XX.X% net rate quarter expectations QX dilution. XX and million diluted by average option last up Our with driven of our year of in was shares year-over-year tax in line share and and impact
million cash million net of Turning cash was million. was QX continuing deducting the operations to through sheet, flow free balance approximately $XXX $XXX $XXX capital expenditures flow cash after and flow from and
$XX approximately buybacks During billion QX to shareholders of capital we dividends. $X.X with returned and in million share
process the QIAGEN started we issuance we QX debt. the for U.S. we notes. for cash In $X securing March And $X.X denominated ended billion the raised of In billion the late and financing acquisition. of approximately permanent quarter dollar of in $XX total billion with senior
was euro after XX.X% leverage from quarter at end of total up on the the notes. the raised my denominated as company Shortly XX times issuance performance, net €X.X Our last we billion additional was ratio we EBITDA to through continue gross the returns. debt adjusted adjusted up of an debt basis. senior X.X on And to year times comments basis very generate three ROIC our end a wrapping points QX quarter strong
the Now on of color the for four quarter. provide segments business performance some our you with
and Before revenue resulted and lab The different of I in the growth services. get into to headwind for of for for the Diagnostics, tailwind Analytical on COVID-XX tailwinds those net and slight quarter. had a a slight details, Specialty headwind in Life-Science I segments organic COVID-XX headwind and Instruments Solutions that impacts in note products mid-teens wanted levels the
specialty than a the To were pieces mainly half more services. evenly testing the realized and to diagnostics were tailwinds The tailwinds kits. Life-Science starting little lab into spread Solutions the of that in tailwinds, products break rest and between with relating the two
the approximately spread About segment and that incurred rest segments. in headwinds, Instruments of two quarter the the Analytical business Solutions the China. were by were our largely headwinds the driven remaining a among Life-Science in to Moving half in scale
was XX% quarter we So production XX%, sciences strong Science in the growth XX% Life moving pull-through we and and businesses. revenue investments was continued Science points on drove Solutions Life Solutions, the bio adjusted very adjusted see mix. by offset segment increased year-over-year. income strategic volume up with operating In QX was XXX growth revenue operating In to which basis quarter to genetic led strong in productivity, details, the margin reported this XX%. starting organic segment and QX partially by and this in business segment in increased and
In Instruments XX%. XX% organic the by QX Analytical declined decreased reported revenue in segment, and revenue
strong the mentioned to of the in negative I for significant couple comps in as in quarters, segment the this earlier, was the all segment. impact this the case of very growth also prior-year we was COVID-XX businesses and As past businesses had
QX volumes more by XXX quarter, the decreased basis adjusted down operating XX.X%, margin operating lower than pull-through saw in XX% Instruments was business points productivity, adjusted we the mix. and Analytical income very offset on year-over-year. strong was which In and
segment X% this at led a saw the that Turning channel to as divestiture. XXXX. is Clinical Diagnostics end QX a by strong divested and Transplant included previously from we business, and Specialty which Diagnostics segment, segment, of growth this reminder, businesses. Anatomical the X% which the decreased included the in We market headwind our Adjusted Pathology operating income Healthcare our
was down prior we year. basis operating margin leverage. productivity points XX.X%, In strong from quarter, and volume saw the the Adjusted XX
investments, than business this was However, offset strategic and the divestiture. mix, more by
revenue led basis in adjusted strategic leverage, more the X% XX mix channel. for and quarter, and and strong growth business increased we Adjusted in than was investments, segment points. QX offset increased lower by a segment was the revenue volume in the QX Products the operating the X%. market growth Services and Finally, Laboratory by In segment, within business prior-year but which income and was safety particularly operating pharma X%, In services the acquisitions. and the reported organic the than research margin saw by the was unfavorable recent XX.X%, quarter, was productivity this
guidance, our pandemic ago Marc impact, weeks a to XXXX withdrew the customer earlier, guidance. we So few to annual mentioned due COVID-XX evolving related as turning and
outlook So you the usual and I providing will with not detail today. be
that of on I'll COVID-XX an insights growth. we However, some QX on out. a I of of on, Then guidance you thought some potential range later give impact it organic you thinking the update would plays dependent provide how elements how about for to the are of on be outcomes less are helpful
the So in own hopefully year. your for this will modeling assist you
So start me outcome that how for let many are drive There organic we will framing growth. are the QX quarter. with variables the
estimates and XX, variables somewhere between will growth best XX%. XX%, flat current results a negative Our these play in organic of out how QX
you Let QX. on the color that me outcome - some provide key drive on two variables primarily for the will
First is revenue growth, the and of COVID-XX is scale headwinds, the related market combination scale second of And of underlying related tailwinds. COVID-XX the the our share gain activity.
revenue of additional tailwinds, to the testing somewhere we QX range. kits in the and our by million where up we to or end Regarding this estimate million, $XXX range testing will level between outcomes XX% The using be customers, for growth. our $XXX proprietary determine X% of an undertaken of
headwinds demand, by COVID-XX the of QX, driven underlying is and a the net by gain to largely are operating market reduced in level. range the headwind a This combination at estimate of to driven share altogether XX%. for level XX% growth related is down whether customer the our which be range We or they activity of turn of shut
is chain, of largely this continuity year. supply to has our factor so unaffected Another consider been far the which
relatively manage still of COVID-XX including by our It's businesses that but for demand through worth business. sites, production any our We potential to at is unaffected. need business relatively COVID-XX of the impact and these majority business are bio pharma our large unaffected services noting our parts customer
a up in up country including how supply depend of on the activity, we in of and COVID-XX outcomes the our quickly lifted, chain. are of impact the range on headwinds factors, end customers and speed the combination will they state Where impact their COVID-XX which ramp our for restrictions,
times to rely to that on our right our ability seeing the confident over In we're you challenging our playing and built trusted need great this, years relationships share to across now we've that continue customers your partners globe. remain with the in drive We gains. like with out
and this XX%. at put current as what between you So the somewhere feel be we negative appropriate broad is on a now, this we outcomes of all variables I know for together, for where growth I range mentioned, is best understand to QX. QX the think outside a this involved. it's assessment based flat organic are range, could growth of when we good this but estimate our our this for There time way about circumstances prospects think it's the and but given range, is we
harder call. begin to normal Should level, customer it well-positioned QX beyond level economy to the and revert we're global revenue capture to a demand to gets appropriate Looking more really of an Throughout our crisis, economy customer in relationships. us are we our That of this strengths when better position highlighting even proposition. really an the improves. growth. value customer puts the deepening It's
it I'll assumed now So the FX year. of the move that start up a year revenue. changes full are the is year-over-year With the X% at the to we rates. from an of is in elements X.X% due FX, on million modeling XXXX of for on to over assuming update some to headwind of regards This recent in $XXX or just
that approximately revenue of growth reflects $X.XX million and We Pathology XXXX the in reported business, acquisitions $XXX the $XX we assume dilution million, continue headwinds operating And continuing to of will our $XXX contribute sale XXXX. from completed revenue Anatomical of which respectively. expect to in the and million we're to income
As way a will reminder in and on two the less be extra QX days year. this there the phasing, falls, QX given day calendar one in there's
equates due the in as a the year the for completed is to result due interest for the the per $XXX costs impact be million deposits cost increase for of pre-funding $X.XX QIAGEN million million. expect This on of higher rates. offerings of to lower income the is bond interest expectation initial is earnings share on acquisition. increase adjusted than remainder recently our of to $XX year, for net the The to the XXXX. $XXX interest approximately We This recent cash reduction
will about income adjusted million assuming $XX be year. the other We're net for
to $X year capital the is net for initial of We driven range million the billion. by $XXX the to the timing be than expenditures expectation $XXX lower of in projects. expect This million
And our XXXX, XXX in full-year view is our call. guidance count a million XXX lower diluted all QX. slightly $X.X we of is capital of initial expect deployment, between total share buybacks. provided and estimate which the the than from terms the timing for million In average billion shares. due on of completed will the total unchanged were year to of buybacks QX This share This be the in we of
return shareholders that We're million $XXX from through for assuming to the also year This year. our is approximately capital we'll dividends. original unchanged assumptions of this
the helpful. for color the full So the while to year, not provide - full guidance usual I you additional being that found able hope
things up, you our same strength this current stronger with uncertain the as in and managed industry we To issues we've we'll as the good from an past through leader. will times and exit macro effectiveness can even performance as period very through wrap see manage QX,
With that, over the Ken. to call turn back I'll