Thanks, everyone. morning, good Marc, and
we great you the played As saw quarter. conditions in Market more largely QX. release, our through core well execution, really revenue prior executed out in growth as we our than press guide. X% delivered we'd And expected in organic
additional of offsetting we In the operational and prior EPS, strong really $X.XX, our quarter. included of guide FX headwind that terms by execution through in adjusted beat $X.XX
flow, We also free very $X the delivering with year capped billion strong off XXXX. cash in
year, effectively. environment we very navigated the macro the changing Throughout
continuing our and our for System enabled and business serving as strategic us deliver advance experience strategy all the customers Business for invest while differentiated proven our the in in to differentiated PPI science. financial Our position a world shareholders, leader growth results to and
with and for full GAAP beginning adjusted now the full me We performance, delivered $X.XX $X.XX in $XX.XX in earnings of provide additional our and EPS results. the for Let you some year. on quarter was the year. $XX.XX details EPS QX our
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X%. decreased revenue QX organic core
and million X%, billion In organic organic $X.X core revenue. For reported year we growth year $XXX delivered the billion and revenue X%. pandemic-related therapies of the revenue, $X.XX of testing full was vaccines of and XXXX, decreased and revenue for XXXX,
Turning are The single digits. geography. to the QX, and current region -- the In low digits. our by pandemic-related by in year double year. by organic skewed revenue the growth organic performance in North declined Europe quarter rates revenue declined low America prior
Asia China Pacific digits, the with grew single in digits. declining low mid-single
year, full declining declined Pacific low And low digits. Europe America digits. high with high single the Asia single China single For declined digit. North declined digits, single
and and by investments With respect to quarter. deliver In QX points we $X.XX was XX.X%, delivered operational XXX was realization. the revenue, performance, And billion strategic productivity pandemic-related continued income offset quarter, margin basis operating the good achieved higher adjusted FX. strong partially adjusted lower we our operating last of price This than in exceptionally year. to
our impact of base The macro conditions. cost System. the appropriately strength the given productivity us Business manage our of our It's PPI enabling reflects to
income For year, guide. our the operating adjusted in was prior with and decreased operating line full margin XX.X%, adjusted XX%,
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the gross full year, margin For adjusted XX.X%. was
points details the of on of revenue, XX an Moving of in to quarter over the XX.X% SG&A basis P&L. the improvement year. last QX Adjusted was
XX an expense year, XXXX. SG&A QX. full the to XX.X% For points improvement adjusted $XXX R&D of compared million was in revenue, of was Total basis
innovation. R&D R&D percent a in ongoing in expense our For revenue of manufacturing as our was the investments X.X% $X.XX year, high-impact reflecting billion, full XXXX. was
the line. at below results Looking our
million increase $XXX of Our interest was expense for is $XX million QX $XX expense full million, Net $XX which XXXX. QX net was interest million, lower year-over-year. year than an the
in the million, QX income other expense than Adjusted of FX. $X $XX million primarily net is expense changes higher due This and nonoperating was quarter a XXXX. in to
income other For in million compared full to the XXXX. million adjusted net year, of expense $XX was a a and income net expense $XX of
Our rate lower points the adjusted tax reflecting XX%. XXX points basis year and than our last lower This QX full the quarter in the planning for was year, XXX results tax the of for and activities. was year basis full
were year-over-year, $X shares options. million Average the approximately XXX lower net QX, in share we repurchased diluted billion by in of of XXXX, million driven shortly And after repurchases shares. year-end X January
$X.X through the $XXX was flow $X I and of flow was Full free to after cash $X.X sheet. cash year expenditures. full in million as for earlier, net QX to Turning billion cash year. investing million billion flow operations balance mentioned and shareholders from capital billion. $XXX dividends And the of returned We capital
year, to on billion which committed we by mid-XXXX. Olink, acquisition the $X.X billion $X.X completed we close acquisitions of to invested the During and expect
of We ended cash billion $X.X with debt. the in quarter and billion $XX.X total
basis. EBITDA the end X.Xx debt on was ratio the to and debt at leverage a net Our of quarter adjusted gross X.Xx
we're generating investment strong comments our my XX%, Concluding ROIC performance. the on across the that company on reflecting was total return Adjusted company.
on performance business of our color some provide segments. now X I'll the
our so skew framing revenue couple in margin revenue was and Let comments. address and profile all scale margins. XXXX, some reported higher and realization does segments rates with of segment segment, pricing The that strong to by In growth varies that pandemic-related inflation. execute me we a to of prior continue the start across year, the of
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income XX.X%. margin For and operating XX%, the year, adjusted operating declined adjusted was full
strong Analytical the business. growth in this led Instruments and X%. electron organic X% by growth the The quarter was the segment in reported also increased In segment, microscopy revenue QX, was
reported For we operating up were was adjusted the higher pull-through, year-over-year. points margin year, segment, than FX basis full adjusted XX.X%, is organic offset by this delivered both strong income operating and strategic quarter, partially revenue QX XX% increased XX%, the In In XXX and productivity volume and XXXX. which investments. and
of XX.X%, XX%, was XXX adjusted increase points For and the adjusted increased operating the basis an versus year, margin prior full income year. operating
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favorable mix, by impact we productivity QX, the COVID-XX testing the In delivered business lower was partially -- volume and strong and strategic offset lower of which investments.
XXX full the XX% higher operating XXXX. adjusted and was than XX.X%, operating income For increase XXXX, points adjusted year, margin basis versus an of was
year organic Biopharma Services of been X% phasing and revenue had vaccines in was runoff reported decreased and and within quarter. Pharma lower Services This the segment, the Products Laboratory the in X% revenue revenue expected. business the by Finally, as QX driven XXXX, revenue and therapies of was prior our than
points basis QX is XXXX. year, this X%, operating full which For lower than XXXX. revenue margin adjusted and segment, was operating declined both X% than higher In income were the XX%, XX reported QX and adjusted organic
mix. offset strong delivered is which we more quarter, by the volume than productivity, unfavorable In
year, XX.X%, and operating full XX% basis margin prior For higher than points increase of versus an operating adjusted adjusted was was XXXX. year, XXX the income the
Let adjusted $XX.X turn we're revenue and guidance guidance. me of XXXX range outlined, to guidance And EPS to range of as billion a $XX.XX now Marc $XX. initiating billion $XX.X to
growth core Our revenue the guidance in XXXX. range positive assumes of for X% organic X% to minus
initial from on We're in the that declines conditions XXXX market expected year. low call. market not significantly year digits on in our this framing view assuming shared changed the single the earnings last Our the has the for
to and growth once execution this enable Our to year. strategy System share again Business us take will PPI continue
to In revenue testing to of million year-over-year Our just current revenue and in billion $X.X a therapies represents this total, under pandemic-related revenue. vaccines estimate headwind million of is X% related XXXX of million of $XXX and of $XXX or $X.X $XXX revenue. billion
M&A is year-over-year, $XXX inorganic the X in of months portion XXXX. revenue and expected million to increase revenue revenue of by the CorEvitas of combination Olink
At to FX QX year-over-year to and headwind is an a a current expect be be standpoint, phasing From rates, in the and both neutral tailwind EPS. slight half. offsetting revenue we FX to adjusted expected second in
margins. to Turning
XX.X% between Our guidance adjusted XXXX margins operating assumes XX.X%. and range income
base, outlook. We continue margin manage aggressively reflected to and our this cost in that's
the range of that's In margins, range terms the that the I for driven provided. revenue by
the the continue our us inflation enable the colleagues. to carryover a long-term actions controls, offset to company expected the Business last and the continue underlying of not in largely revenue the PPI are runoff appropriately in investments System place very manage in cost further across to but only right use put year, to benefit to invest including from We'll compensation leadership. cost productivity normalization remaining incentive pandemic-related the Strong carefully, costs and also make to our to industry advance
of interests. million expect We XXXX. that the be will to we and adjusted should income net approximately other in X. factor tax elimination to below XX.X% assume in and rate $XX XXXX line, tax And related minority in of adjusted close profit expense expense to $XXX you interest the Below net income line, million expect
and between assuming capital and XXXX, is free range of $X.X billion we're for expecting the billion billion We're expenditures $X.X net cash and flow $X.X $X in year. the billion in of
close were our will count estimate And completed share the mentioned guidance In we average year be dividends, to billion assuming approximately midyear. through we'll in January. approximately already of which, assuming I acquisition shareholders of capital we're this million by share as full of XXX the return terms deployment, diluted and of buybacks, capital that year Olink shares. earlier, $X million We're we that $XXX assumes
there the few And wanted finally, touch as things year on a to phasing quarterly to for are consider. I
then be during in organic that to revenue X growth First, sequentially QX to during to points organic Implied And better growth second improve in is the expect leading also similar quarter core year. QX half growth core we revenue is in 'XX. quarter in to of than each by expected growth, terms the of organic improve year. revenue the the year, to 'XX each QX QX moderate X and
approximately increase From we share the the and a of margin throughout be year And just quarter earnings XX% standpoint, we that level. expect XX% each QX to per QX adjusted from full to year. under expect be
conclusion, in performance in environment customers shareholders. we stepped We and for successfully. navigated So our for our financial up challenging very delivered XXXX the differentiated
the to forward continue year go We you look agility, manage progress we I and we're really the ahead. our through company the for positioned on to well as year. with updating
With over the Raf. that, call I'll to turn back