Milestone Pharmaceuticals (MIST)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	12.80 mm	12.80 mm	12.80 mm	12.80 mm	12.80 mm	12.80 mm
Cash burn (monthly)	154.33 k	(no burn)	3.21 mm	3.63 mm	2.34 mm	2.65 mm
Cash used (since last report)	781.77 k	n/a	16.24 mm	18.39 mm	11.85 mm	13.42 mm
Cash remaining	12.02 mm	n/a	-3.44 mm	-5.59 mm	949.21 k	-624.88 k
Runway (months of cash)	77.9	n/a	-1.1	-1.5	0.4	-0.2

Beta Read what these cash burn values mean

Financial data from company earnings reports.

Institutional ownership, Q4 2024

MIST institutional ownership history Ownership history

57.2% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	49	46	+6.5%
Opened positions	10	6	+66.7%
Closed positions	7	3	+133.3%
Increased positions	14	9	+55.6%
Reduced positions	13	9	+44.4%

13F shares	Current	Prev Q	Change
Total value	57.75 bn	43.52 bn	+32.7%
Total shares	30.49 mm	34.57 mm	-11.8%
Total puts	38.80 k	0.00	NEW
Total calls	61.20 k	200.00	+30500.0%
Total put/call ratio	0.6	–	–

Largest owners	Shares	Value	Change
BlackRock	4.05 mm	$9.56 bn	-18.5%
Integrated Core Strategies	2.78 mm	$3.97 mm	0.0%
Millennium Management	2.70 mm	$6.38 bn	-2.7%
Alta Fundamental Advisers	2.66 mm	$6.27 bn	0.0%
RTW Investments	2.51 mm	$5.91 bn	-23.0%
Orbimed Advisors	2.00 mm	$4.72 bn	0.0%
Nantahala Capital Management	1.45 mm	$3.41 bn	-17.4%
Fonds De Solidarite Des Travailleurs Du Quebec	1.39 mm	$9.30 mm	0.0%
Bleichroeder	1.33 mm	$3.13 bn	0.0%
MS Morgan Stanley	1.29 mm	$3.04 bn	+40.4%

Largest transactions	Shares	Bought/sold	Change
Citadel Advisors	608.20 k	-1.45 mm	-70.5%
BlackRock	4.05 mm	-920.66 k	-18.5%
TD The Toronto-Dominion Bank	750.00 k	+750.00 k	NEW
RTW Investments	2.51 mm	-750.00 k	-23.0%
Lion Point Capital	1.03 mm	-628.35 k	-38.0%
Stonepine Capital Management	500.00 k	-499.79 k	-50.0%
Altium Capital Management	0.00	-440.00 k	EXIT
GS The Goldman Sachs Group, Inc.	942.41 k	-410.66 k	-30.4%
MS Morgan Stanley	1.29 mm	+370.83 k	+40.4%
Boxer Capital Management	309.01 k	+309.01 k	NEW

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

MIST insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
27 Jan 25	Jeffrey Edward Nelson	RSU Common Shares	Grant	Acquire A	No	No	0	80,400	0.00	80,400
27 Jan 25	Jeffrey Edward Nelson	Employee Stock Option Common Shares	Grant	Acquire A	No	No	2.02	120,600	243.61 k	120,600
27 Jan 25	Hasija Amit	RSU Common Shares	Grant	Acquire A	No	No	0	80,400	0.00	80,400
27 Jan 25	Hasija Amit	Employee Stock Option Common Shares	Grant	Acquire A	No	No	2.02	120,600	243.61 k	120,600
27 Jan 25	David Bharucha	RSU Common Shares	Grant	Acquire A	No	No	0	80,400	0.00	80,400
27 Jan 25	David Bharucha	Employee Stock Option Common Shares	Grant	Acquire A	No	No	2.02	120,600	243.61 k	120,600
27 Jan 25	Oliveto Joseph	RSU Common Shares	Grant	Acquire A	No	No	0	266,400	0.00	266,400
27 Jan 25	Oliveto Joseph	Employee Stock Option Common Shares	Grant	Acquire A	No	No	2.02	399,600	807.19 k	399,600
27 Jan 25	Muller Lorenz	RSU Common Shares	Grant	Acquire A	No	No	0	80,400	0.00	80,400
27 Jan 25	Muller Lorenz	Employee Stock Option Common Shares	Grant	Acquire A	No	No	2.02	120,600	243.61 k	120,600

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.

News

From Benzinga Pro

HC Wainwright & Co. Reiterates Buy on Milestone Pharmaceuticals, Maintains $25 Price Target

28 Feb 25

HC Wainwright & Co. analyst Patrick Trucchio reiterates Milestone Pharmaceuticals (NASDAQ:MIST) with a Buy and maintains $25 price target.

HC Wainwright & Co. Reiterates Buy on Milestone Pharmaceuticals, Maintains $25 Price Target

27 Jan 25

HC Wainwright & Co. analyst Patrick Trucchio reiterates Milestone Pharmaceuticals (NASDAQ:MIST) with a Buy and maintains $25 price target.