Impel Pharmaceuticals (IMPL)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	4.74 mm	4.74 mm	4.74 mm	4.74 mm	4.74 mm	4.74 mm
Cash burn (monthly)	3.47 mm	6.25 mm	4.60 mm	6.92 mm	5.51 mm	6.59 mm
Cash used (since last report)	59.27 mm	106.63 mm	78.57 mm	118.05 mm	93.98 mm	112.46 mm
Cash remaining	-54.53 mm	-101.89 mm	-73.83 mm	-113.31 mm	-89.24 mm	-107.72 mm
Runway (months of cash)	-15.7	-16.3	-16.0	-16.4	-16.2	-16.3

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Financial data from company earnings reports.

Institutional ownership, Q3 2023

IMPL institutional ownership history Ownership history

13F holders	Current	Prev Q	Change
Total holders	35	36	-2.8%
Opened positions	5	2	+150.0%
Closed positions	6	1	+500.0%
Increased positions	4	4	–
Reduced positions	6	5	+20.0%

13F shares	Current	Prev Q	Change
Total value	7.52 bn	22.45 bn	-66.5%
Total shares	30.03 mm	29.30 mm	+2.5%
Total puts	0.00	0.00
Total calls	0.00	0.00
Total put/call ratio	–	–	–

Largest owners	Shares	Value	Change
Kohlberg Kravis Roberts & Co.	4.14 mm	$1.78 bn	0.0%
KKR Iris Investors	3.80 mm	$57.23 mm	0.0%
NVP Associates	3.08 mm	$1.32 bn	0.0%
5AM Venture Management	2.88 mm	$1.24 bn	0.0%
Vivo Capital VIII	2.88 mm	$43.42 mm	0.0%
Vivo Capital	2.88 mm	$1.24 bn	0.0%
venBio Global Strategic Fund II	2.76 mm	$41.54 mm	0.0%
venBio Partners	2.76 mm	$1.19 bn	0.0%
5AM Ventures V	2.31 mm	$34.76 mm	0.0%
OAK-PA Oaktree Capital Group, LLC 6.625% PFD UT A	1.21 mm	$477.00 k	NEW

Largest transactions	Shares	Bought/sold	Change
OAK-PA Oaktree Capital Group, LLC 6.625% PFD UT A	1.21 mm	+1.21 mm	NEW
Lasry Marc	225.87 k	-182.46 k	-44.7%
DCF Advisers	178.50 k	-125.11 k	-41.2%
Laurion Capital Management	0.00	-124.80 k	EXIT
Bridgeway Capital Management	0.00	-63.30 k	EXIT
J. Goldman & Co	0.00	-49.57 k	EXIT
Millennium Management	21.49 k	+21.49 k	NEW
XTX Topco	21.22 k	+21.22 k	NEW
Two Sigma Securities	20.46 k	+20.46 k	NEW
Geode Capital Management	172.22 k	+17.26 k	+11.1%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

IMPL insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value
5 Apr 24	Timothy S Nelson	Common Stock	Other	Dispose J	No	No	0	10,000	0.00
5 Apr 24	Timothy S Nelson	Stock Option Common Stock	Other	Dispose J	No	No	1.34	13,222	17.72 k
5 Apr 24	Timothy S Nelson	Stock Option Common Stock	Other	Dispose J	No	No	8.65	12,789	110.62 k
5 Apr 24	Timothy S Nelson	Stock Option Common Stock	Other	Dispose J	No	No	9.96	11,500	114.54 k
5 Apr 24	Timothy S Nelson	Stock Option Common Stock	Other	Dispose J	No	No	2.95	22,325	65.86 k
5 Apr 24	Timothy S Nelson	Stock Option Common Stock	Other	Dispose J	No	No	2.46	3,053	7.51 k
5 Apr 24	Timothy S Nelson	Stock Option Common Stock	Other	Dispose J	No	No	1.97	12,303	24.24 k
5 Apr 24	Wilfong Diane E.	Stock Option Common Stock	Other	Dispose J	No	No	1.34	13,222	17.72 k
5 Apr 24	Wilfong Diane E.	Stock Option Common Stock	Other	Dispose J	No	No	8.65	12,789	110.62 k
5 Apr 24	Wilfong Diane E.	Stock Option Common Stock	Other	Dispose J	No	No	9.96	11,500	114.54 k

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.