CRISPR Therapeutics (CRSP)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	294.50 mm	294.50 mm	294.50 mm	294.50 mm	294.50 mm	294.50 mm
Cash burn (monthly)	(no burn)	(no burn)	44.02 mm	47.87 mm	28.21 mm	25.21 mm
Cash used (since last report)	n/a	n/a	189.52 mm	206.08 mm	121.46 mm	108.53 mm
Cash remaining	n/a	n/a	104.99 mm	88.43 mm	173.05 mm	185.98 mm
Runway (months of cash)	n/a	n/a	2.4	1.8	6.1	7.4

Beta Read what these cash burn values mean

Financial data from company earnings reports.

Institutional ownership, Q4 2024

CRSP institutional ownership history Ownership history

83.5% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	404	418	-3.3%
Opened positions	68	44	+54.5%
Closed positions	82	81	+1.2%
Increased positions	113	128	-11.7%
Reduced positions	116	127	-8.7%

13F shares	Current	Prev Q	Change
Total value	2.32 tn	2.54 tn	-8.8%
Total shares	79.61 mm	74.53 mm	+6.8%
Total puts	1.92 mm	1.90 mm	+1.5%
Total calls	1.55 mm	1.10 mm	+41.1%
Total put/call ratio	1.2	1.7	-28.1%

Largest owners	Shares	Value	Change
ARK Investment Management	8.97 mm	$353.18 bn	+19.7%
Capital International Investors	8.74 mm	$344.15 bn	+10.3%
VRTX Vertex Pharmaceuticals	5.38 mm	$353.37 mm	0.0%
T. Rowe Price Investment Management	3.81 mm	$150.03 mm	+39.2%
GSK GSK	3.31 mm	$278.46 mm	0.0%
Bayer Global Investments B.V.	2.95 mm	$154.89 mm	0.0%
BLK BlackRock	2.76 mm	$108.61 bn	-1.3%
CMTDF Sumitomo Mitsui Trust	2.75 mm	$108.07 bn	-7.5%
Nikko Asset Management Americas	2.75 mm	$108.07 bn	-7.5%
STT State Street	2.49 mm	$98.07 bn	-16.8%

Largest transactions	Shares	Bought/sold	Change
Orbis Allan Gray	1.48 mm	+1.48 mm	NEW
ARK Investment Management	8.97 mm	+1.47 mm	+19.7%
UBS UBS	1.98 mm	+1.31 mm	+194.5%
T. Rowe Price Investment Management	3.81 mm	+1.07 mm	+39.2%
Capital International Investors	8.74 mm	+816.79 k	+10.3%
Contrarius Investment Management	0.00	-783.90 k	EXIT
BLVGF Bellevue	0.00	-610.00 k	EXIT
STT State Street	2.49 mm	-501.46 k	-16.8%
Baker Bros. Advisors	1.31 mm	+464.94 k	+55.1%
FHI Federated Hermes	0.00	-447.61 k	EXIT

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

CRSP insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
22 Jan 26	Raju Prasad	Common Shares	Sell	Dispose S	No	Yes	60.19	34,972	2.10 mm	6,767
22 Jan 26	Raju Prasad	Common Shares	Option exercise	Acquire M	No	No	45.15	34,972	1.58 mm	41,739
22 Jan 26	Raju Prasad	Stock Option Common Shares	Option exercise	Dispose M	No	No	45.15	34,972	1.58 mm	41,667
22 Jan 26	Samarth Kulkarni	Common Shares	Sell	Dispose S	No	Yes	60.23	60,000	3.61 mm	134,201
20 Jan 26	Samarth Kulkarni	Common Shares	Sell	Dispose S	No	Yes	52.1	8,567	446.34 k	194,201
20 Jan 26	Samarth Kulkarni	Common Shares	Sell	Dispose S	No	Yes	51.61	21,433	1.11 mm	202,768
6 Jan 26	Raju Prasad	Common Shares	Sell	Dispose S	No	Yes	60.2134	5,763	347.01 k	6,767
6 Jan 26	Raju Prasad	Common Shares	Sell	Dispose S	No	Yes	60	5,004	300.24 k	12,530
6 Jan 26	Raju Prasad	Common Shares	Sell	Dispose S	No	Yes	60.1799	18,933	1.14 mm	17,534
6 Jan 26	Raju Prasad	Common Shares	Option exercise	Acquire M	No	No	44.31	6,339	280.88 k	36,467

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.