| Quarter (USD) | Sep 25 | Jun 25 | Mar 25 | Dec 24 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Annual (USD) | Dec 24 | Dec 23 | Dec 22 | Dec 21 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Cash burn rate (est.) | Burn method: Change in cash | Burn method: Operating income | Burn method: FCF (opex + capex) | Last Q | Avg 4Q | Last Q | Avg 4Q | Last Q | Avg 4Q |
|---|---|---|---|---|---|---|
| Cash on hand (at last report) | 47.01 mm | 47.01 mm | 47.01 mm | 47.01 mm | 47.01 mm | 47.01 mm |
| Cash burn (monthly) | 3.19 mm | 3.44 mm | 6.94 mm | 8.49 mm | 3.85 mm | 7.20 mm |
| Cash used (since last report) | 7.36 mm | 7.94 mm | 15.99 mm | 19.57 mm | 8.88 mm | 16.61 mm |
| Cash remaining | 39.65 mm | 39.07 mm | 31.02 mm | 27.44 mm | 38.13 mm | 30.41 mm |
| Runway (months of cash) | 12.4 | 11.4 | 4.5 | 3.2 | 9.9 | 4.2 |
| 13F holders | Current |
|---|---|
| Total holders | 117 |
| Opened positions | 34 |
| Closed positions | 11 |
| Increased positions | 28 |
| Reduced positions | 27 |
| 13F shares | Current |
|---|---|
| Total value | 88.26 bn |
| Total shares | 27.46 mm |
| Total puts | 1.08 mm |
| Total calls | 1.80 mm |
| Total put/call ratio | 0.6 |
| Largest owners | Shares | Value |
|---|---|---|
| FMR | 5.44 mm | $21.09 bn |
| Cormorant Asset Management | 3.57 mm | $13.85 bn |
| Cormorant Global Healthcare Master Fund | 3.57 mm | $114.09 mm |
| BlackRock | 2.22 mm | $8.61 bn |
| Baker Bros. Advisors | 1.45 mm | $5.63 bn |
| Vanguard | 1.40 mm | $5.44 bn |
| Aisling Capital Management | 798.76 k | $3.10 bn |
| STT State Street | 604.36 k | $2.34 bn |
| Geode Capital Management | 604.15 k | $2.34 bn |
| Two Sigma Investments | 559.93 k | $2.17 bn |
| Date | Owner | Security | Transaction | Code | Indirect | 10b5-1 | $Price | #Shares | $Value | #Remaining |
|---|---|---|---|---|---|---|---|---|---|---|
| 2 Dec 25 | Michael J.M. Hitchcock | Common Stock | Buy | Acquire P | No | No | 0.9918 | 100,000 | 99.18 k | 115,000 |
| 1 Dec 25 | Rainer M Erdtmann | Common Stock | Buy | Acquire P | No | No | 1.05 | 10,000 | 10.50 k | 693,027 |
| 28 Nov 25 | Rainer M Erdtmann | Common Stock | Buy | Acquire P | No | No | 1.1013 | 40,000 | 44.05 k | 683,027 |
| 11 Aug 25 | Michael J.M. Hitchcock | Stock Option Common Stock | Grant | Acquire A | No | No | 1.53 | 916,434 | 1.40 mm | 916,434 |
