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Exhibit 23
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statements of Echo Therapeutics, Inc. (formerly Sontra Medical Corporation) onForm S-8 (File Nos.333-152138,333-92414,333-101517,333-106201,333-122893,333-134674,333-143145 and333-146607), of our report dated April 9, 2009, relating to the consolidated financial statements for the years ended December 31, 2008 and 2007, which is part of thisForm 10-K. Our report dated April 9, 2009 relating to the consolidated financial statements includes an emphasis paragraph relating to an uncertainty as to the Company’s ability to continue as a going concern.
Wolf & Company, P.C.
Boston, Massachusetts
April 9, 2009