limitation, Employee’s agreeing to refrain from performing services pursuant to a covenant not to compete or similar covenant) before, on or after the date of a change in ownership or control of the Company (within the meaning ofQ&A-2(b) of Section 280G of the Code), such that payments in respect of such services (or refraining from performing such services) may be considered reasonable compensation within the meaning ofQ&A-9 andQ&A-40 toQ&A-44 of Section 280G of the Code and/or exempt from the definition of the term “parachute payment” within the meaning ofQ&A-2(a) of Section 280G of the Code in accordance withQ&A-5(a) of Section 280G of the Code.”
(a) Section 1(a) of your Noncompete Agreement is hereby amended and restated to read as follows:
“(a) During the term of Employee’s employment with the Company and for a period of 24 months thereafter, Employee shall not, directly or indirectly own, manage, operate, control, be employed by, serve as a consultant to or otherwise participate in any business (a “Competitive Business”) involving the manufacturing, development and commercialization within the United States of (i) BRAF kinase inhibitors that selectively target BRAF V600E, or (ii) reversible,ATP-uncompetitive, allosteric inhibitors of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2 activity for the treatment of cutaneous metastatic melanoma as first-line or second-line therapy, or colorectal cancer as a second-line or later round of therapy (each a “Product” and collectively “Products”); provided, however that (i) a Competitive Business shall not include Products that are expected to be used, or are used, as adjuvant (or add on) therapy to the Company’s Product that do not otherwise fall within this Section 1(a), (ii) Employee shall not be deemed in violation of this restriction to the extent he is employed by or consults with a company or business that generates less than 10% of its aggregate annual revenues from a Competitive Business at the time of initial employment or consultancy and (iii) Employee shall not be deemed in violation of this restriction to the extent he only owns a passive investment equity interest in a company engaged in a Competitive Business.”
(b) If after the Closing you seek the Company’s view as to whether a particular opportunity would violate the noncompetition covenant set forth in your Noncompete Agreement (as modified by this Section 3 of the letter agreement), subject to your provision to the Company of sufficient information for the Company to assess the opportunity (including your proposed role and the business proposed to be undertaken), the Company shall provide you with its view as soon as reasonably practicable following its receipt of all relevant information. Your agreement to, and compliance with, the restrictive covenants set forth in your Noncompete Agreement (as modified by this Section 3 of the letter agreement) is a condition of your receipt of all compensation and benefits contemplated by this letter agreement (including the adjustment of the severance formula contemplated by Section 1 of this letter agreement and the Retention Award). Accordingly, you agree that, in the event of your violation of any such restrictive
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